For a long time, the cure for diabetes type 1 and type 2 has relied on agonizing insulin shots for patients or insulin infusion via mechanical pumps. Regarding this, experts have been creating artificial pancreatic beta cells with the he…
Chenodeoxycholic acid is a bile acid that is used to treat gallstones. Other names for chenodeoxycholic acid include: Chenodiol, Chenic Acid, and CDCA. It occurs as a white crystalline substance insoluble in water but soluble in alcohol and acetic acid, with melting point at 165-167°C. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids produced by the liver. It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name.
Chenodeoxycholic acid and cholic acid are the two primary bile acids in humans. Some other mammals have muricholic acid or deoxycholic acid rather than chenodeoxycholic acid.
Chenodeoxycholic acid is synthesized in the liver from cholesterol by a process which involves several enzymatic steps. Like other bile acids, it can be conjugated in the liver with taurine or glycine, forming taurochenodeoxycholate or glycochenodeoxycholate. Conjugation results in a lower pKa. This means the conjugated bile acids are ionized at the usual pH in the intestine and will stay in the gastrointestinal tract until reaching the ileum where most will be reabsorbed. Bile acids form micelles which facilitate lipid digestion. After absorption, they are taken up by the liver and resecreted, so undergoing an enterohepatic circulation. Unabsorbed chenodeoxycholic acid can be metabolised by bacteria in the colon to form the secondary bile acid known as lithocholic acid.
The global chenodeoxycholic acid production, which measures output worldwide, was expected to reach xx tons in 2016 with an increase of xx% from its year-earlier level. The global chenodeoxycholic acid market size is estimated to grow from USD xx million in 2011 to USD xx million by 2016, at an estimated CAGR of xx% between 2011 and 2016. With regards to this, key players of chenodeoxycholic acid industry are expected to find potential opportunities in this market.
The global chenodeoxycholic acid market report profiles some of the key technological developments in the recent times. It also profiles some of the leading players in the market and analyzes their key strategies. The competitive landscape section of the report provides a clear insight into the market share analysis of key industry players. The major players in the global chenodeoxycholic acid market are ICE, Tianli Biochemical, Zhongshan Belling, Suzhou Tianlu, Hengchanglong, etc.
The global chenodeoxycholic acid industry is relatively concentrated, with the market share of top 5 chenodeoxycholic acid producers at xx%.