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Spine Biologics Market by Product Type (Bone Graft, Bine Graft Substitute, Platelet Rich Plasma, BMAC), Surgery Type (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion), End User, and Geography - Global Forecast to 2020

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Date: 24-Nov-2015
No. of pages: 101
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Spine Biologics Market, By Product (Bone Grafts, Bone Grafts Substitutes, Platelet-rich Plasma, Bone Marrow Aspirate Therapy), By Surgery Type (Anterior Cervical Discectomy and Fusion (ACDF), Posterior Lumbar Interbody Fusion (PLIF), Transforaminal Lumbar Interbody Fusion (TLIF), Anterior Lumbar Interbody Fusion (ALIF), Lateral Lumbar Interbody Fusion (LLIF)), by Geography– Global Forecasts to 2020

Spinal biologics are devices that are used extensively f or bone fusion surgery, spinal cord injury, and degenerative disk disease. The treatment may include the use of allografts, autografts, mesenchymal stem cells, demineralized bone matrix, bone morphogenetic protein, and ceramics. These materials assist the body’s natural healing processes and are used to heal spine diseased or degenerated discs. The effects is perceived through increased cellular activity, growth, and differentiation. For example, in case of materials such as pedicle rods and screws used in spine fusion cases to provide spinal stability and fusion healing. However, since metals are inert in nature, they do not stimulate or activate cellular growth or alter cellular functions such as natural healing. Biologic materials are increasingly being preferred by surgeons performing spinal fusion surgeries as their use facilitates the fusion process due to their stimulant effect on spine fusion. The global spine biologics market constituted 33.5% of the global spinal implants and spinal devices market in 2014.

Spine biologics find application in spine surgery as lieu allografts as well as a support for bones in and around the spinal region. They can also be used cure the spinal injuries or trauma or degenerated discs. Currently, bone morphogenetic proteins (BMP’s) are biologic materials that are predominantly used in spinal surgery. Bone graft substitutes claim for around 85% share of the total spine biologics market.

The global spine biologics market size is expected to reach $2.4billion by 2020, at a CAGR of 4.4% during the forecast period of 2015 to 2020. Growing aging population and rise in the application of minimally invasive surgeries are the major factors influencing the growth of this market.

The global spine biologics market report studies the major regions, namely, North America, Europe, Asia-Pacific, and Rest of the World (RoW).

In 2014, North America estimated accounted for the largest share of the global spine biologics market. As growth of healthcare industry is affected by the healthcare expenditure, increased investments in life sciences are expected to fuel the growth of the global spine biologics market in this region. The European spine biologics market is the second-largest. APAC is estimated to be the fastest growing market for spine biologics during the forecast period.

The report includes company profiles of major players, recent activities in the market, new product launches, mergers & acquisitions, collaborations and partnerships, and SWOT analysis. Some of the companies profiled in this report are Medtronic Inc. (U.S.), DePuy Synthes Companies (U.S.), Zimmer Holding Inc. (U.S.), Nuvasive Inc. (U.S.), Stryker Corporation (U.S.), Orthofix International N.V. (U.S.), K2M Inc. (U.S.), Exactech Inc. (U.S.), and Wright Medical Technology Inc. (U.S.),among others.

Reasons to Buy the Report:

From an insight perspective, this research report has focused on various levels of analysis, namely, industry analysis (industry trends and PEST analysis), market share analysis of top players, supply chain analysis, and company profiles. All of these together comprise and discuss the basic views on the competitive landscape, usage patterns, emerging- and high-growth segments, high-growth regions and countries and their respective regulatory policies, government initiatives, drivers, restraints, and opportunities for the global spine biologics market.

The report will enrich both established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in turn will help them garner a greater market share. Firms purchasing the report could use any one or a combination of the below mentioned five strategies to strengthen their market share.

The report provides insights on the following pointers:


  • Product Analysis and Development: Detailed insights on upcoming technologies, research and development activities, and new product launches in the global spine biologics market are provided.

  • Market Development: Comprehensive information about lucrative emerging markets is provided. The report also analyzes the markets for spine biologics across various regions, exploit new distribution channels, new clientele base, and different pricing policies.

  • Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments decisions in the Global spine biologics market is provided. Detailed description regarding the related and unrelated diversification pertaining to this market is also provided.

  • Competitive Assessment: An in-depth assessment of market shares and company share analysis of the key players forecasted till 2020 is provided.

Spine Biologics Market by Product Type (Bone Graft, Bine Graft Substitute, Platelet Rich Plasma, BMAC), Surgery Type (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion), End User, and Geography - Global Forecast to 2020

Table of Contents

1 Introduction
1.1 Objectives of the Study
1.2 Market Segmentation & Coverage
1.3 Stakeholders

2 Research Methodology
2.1 Integrated Ecosystem of Spine Biologics Market
2.2 Arriving at the Spine Biologics Market Size
2.2.1 Top-Down Approach
2.2.2 Bottom-Up Approach
2.2.3 Macro Indicator-Based Approach
2.3 Assumptions

3 Executive Summary

4 Market Overview
4.1 Introduction
4.2 Market Drivers and Inhibitors

5 Spine Biologics Market, By Surgery Type
5.1 Introduction
5.2 Anterior Cervical Discectomy and Fusion (ACDF)
5.3 Posterior Lumbar Interbody Fusion (PLIF)
5.4 Transforaminal Lumbar Interbody Fusion (TLIF)
5.5 Anterior Lumbar Interbody Fusion (ALIF)
5.6 Lateral Lumbar Interbody Fusion (LLIF)
5.7 Others

6 Spine Biologics Market By Product Type
6.1 Introduction
6.2 Bone Graft
6.2.1 Autograft
6.2.2 Allograft
6.3 Bone Graft Substitutes
6.3.1 Synthetic Bone Grafts
6.3.2 Demineralized Bone Matrix (DBM)
6.3.3 Bone Morphogenetic Proteins (BMP)
6.4 Platelet Rich Plasma (PRP)
6.5 Bone Marrow Aspirate (BMAC) Therapy

7 Spine Biologics Market, By Geography
7.1 Introduction
7.2 North America
7.2.1 Spine Biologics Market, By Country
7.2.2 Market, By Product Type
7.2.3 Bone Graft Substitutes Market, By Product Type
7.2.4 Market, By Surgery Type
7.3 Europe
7.3.1 Market, By Country
7.3.2 Market, By Product Type
7.3.3 Bone Graft Substitutes Market, By Product Type
7.3.4 Market, By Surgery Type
7.4 Asia Pacific
7.4.1 Market, By Country
7.4.2 Market, By Product Type
7.4.3 Bone Graft Substitutes Market, By Product Type
7.4.4 Market, By Surgery Type

8 Competitive Landscape
8.1 Company Share Analysis
8.2 Product Launches
8.3 Mergers and Acquisitions
8.4 Collaborations, Joint Agreements & Expansions, Partnerships
8.5 Approvals, Alliances, Relocation & Licensing

9 Company Profiles
(Overview, Financials, Products & Services, Strategy, and Developments)*
9.1 Zimmer Holding, Inc.
9.2 Depuy Synthes
9.3 Medtronic, Inc. (U.S.)
9.4 Nuvasive, Inc.
9.5 Stryker Corporation
9.6 Orthofix International N.V.
9.7 K2M, Inc.
9.8 Exactech, Inc.
9.9 Wright Medical Technology, Inc.
9.10 Nutech
9.11 Arthrex, Inc.
9.12 X-Spine Systems, Inc. (Bacterin International Holdings, Inc.)
9.13 DR PRP USA LLC

*Details on Overview, Financials, Product & Services, Strategy, and Developments Might Not Be Captured in Case of Unlisted Company

10 Appendix
10.1 Introducing RT: Real-Time Market Intelligence
10.2 Customization Options
10.2.1 Product Analysis
10.2.2 Spine Surgeons/ Doctors Perception Analysis
10.2.3 Regulatory Framework
10.2.4 Competitive Intelligence
10.3 Related Reports

List of Tables

Table 1 Spine Biologics Market: Healthcare Expenditure, By Geography, 2014 (USD Million)
Table 2 Spine Biologics Market, By Product Type, 2013-2020 (USD Million)
Table 3 Spine Biologics Market, By Surgery Type, 2013-2020 (USD Million)
Table 4 Spine Biologics Market, By Geography, 2013-2020 (USD Million)
Table 5 Drivers and Inhibitors
Table 6 Spine Biologics Market, By Surgery Type, 2013-2020 (USD Million)
Table 7 Spine Biologics Market in Anterior Cervical Discectomy and Fusion (ACDF) Surgery, By Product Type, 2013-2020 (USD Million)
Table 8 Spine Biologics Market in Anterior Cervical Discectomy and Fusion (ACDF) Surgery, By Geography, 2013-2020 (USD Million)
Table 9 Spine Biologics Market in Transforaminal Lumbar Interbody Fusion (TLIF) Surgery, By Product Type, 2013-2020 (USD Million)
Table 10 Spine Biologics Market in Transforaminal Lumbar Interbody Fusion (TLIF) Surgery, By Geography, 2013-2020 (USD Million)
Table 11 Spine Biologics Market in Anterior Lumbar Interbody Fusion (ALIF) Surgery, By Product Type, 2013-2020 (USD Million)
Table 12 Spine Biologics Market in Anterior Lumbar Interbody Fusion (ALIF) Surgery, By Geography, 2013-2020 (USD Million)
Table 13 Spine Biologics Market in Lateral Lumbar Interbody Fusion (LLIF) Surgery, By Product Type, 2013-2020 (USD Million)
Table 14 Spine Biologics Market in Lateral Lumbar Interbody Fusion (LLIF) Surgery, By Geography, 2013-2020 (USD Million)
Table 15 Market Value By Product Type, 2013-2020 (USD Million)
Table 16 Bone Grafts Market Value By Surgery Type, 2013-2020 (USD Million)
Table 17 Bone Grafts Market Value By Geography, 2013-2020 (USD Million)
Table 18 Bone Graft Substitutes Market Value By Product Type, 2013-2020 (USD Million)
Table 19 Synthetic Bone Grafts Market Value By Surgery Type, 2013-2020 (USD Million)
Table 20 Synthetic Bone Grafts Market Value By Geography, 2013-2020 (USD Million)
Table 21 Demineralized Bone Matrix (DBM) Market Value By Surgery Type, 2013-2020 (USD Million)
Table 22 Demineralized Bone Matrix (DBM) Market Value By Geography, 2013-2020 (USD Million)
Table 23 Bone Morphogenetic Protein (BMP) Market Value By Surgery Type, 2013-2020 (USD Million)
Table 24 Bone Morphogenetic Protein (BMP) Market Value By Geography, 2013-2020 (USD Million)
Table 25 Platelet Rich Plasma (PRP) Market Value By Geography, 2013-2020 (USD Million)
Table 26 Bone Marrow Aspirate Concentrate (BMAC) Therapy Market Value By Geography, 2013-2020 (USD Million)
Table 27 Spine Biologics Market Size, By Geography, 2013 – 2020 (USD Million)
Table 28 North America: Market, By Country, 2013-2020 (USD Million)
Table 29 North America: Market, By Product Type, 2013-2020 (USD Million)
Table 30 North America: Bone Graft Substitutes Market, By Product Type, 2013-2020 (USD Million)
Table 31 North America: Market, By Surgery Type, 2013-2020 (USD Million)
Table 32 Europe: Market, By Country, 2013-2020 (USD Million)
Table 33 Europe: Market, By Product Type, 2013-2020 (USD Million)
Table 34 Europe: Bone Graft Substitutes Market, By Product Type, 2013-2020 (USD Million)
Table 35 Europe: Market, By Surgery Type, 2013-2020 (USD Million)
Table 36 Asia Pacific: Market, By Country, 2013-2020 (USD Million)
Table 37 Asia Pacific: Market, By Product Type, 2013-2020 (USD Million)
Table 38 Asia Pacific: Bone Graft Substitutes Market, By Product Type, 2013-2020 (USD Million)
Table 39 Asia Pacific: Market, By Surgery Type, 2013-2020 (USD Million)
Table 40 Company Share Analysis, 2014
Table 41 Product Launches
Table 42 Mergers and Acquisitions
Table 43 Collaborations, Joint Agreements & Expansions
Table 44 Approvals, Alliances, Relocation & Licensing
Table 45 Zimmer Holding, Inc.: Revenue, By Business Segment, 2009-2014 (USD Million)
Table 46 Johnson & Johnson Ltd.: Revenue, By Business Segment, 2011-2014 (USD Million)
Table 47 Medtronic, Inc. : Revenue, By Business Segment, 2009-2013 (USD Million)
Table 48 Nuvasive, Inc.: Revenue, By Product Type, 2010-2014 (USD Million)
Table 49 Stryker Corporation.: Revenue, By Business Segment, 2010-2014 (USD Million)
Table 50 Orthofix Holdings, Inc.: Revenue, By Business Segment, 2012-2014 (USD Million)
Table 51 K2M Inc.: Revenue, 2011-2014 (USD Million)
Table 52 Exactech, Inc.: Revenue, By Business Segment, 2010-2014 (USD Million)
Table 53 Exactech, Inc.: Key Financials, By Geography, 2010-2014 (USD Million)
Table 54 Wright Medical Technology, Inc.: Revenue, By Business Segment, 2011-2013 (USD Million)
Table 55 Wright Medical Technology, Inc.: Revenue, By Geography, 2011-2013 (USD Million)

List of Figures

Figure 1 Segmentation & Coverage
Figure 2 Integrated Ecosystem
Figure 3 Research Methodology
Figure 4 Top-Down Approach
Figure 5 Bottom-Up Approach
Figure 6 Macro Indicator-Based Approach (2014)
Figure 7 Market Snapshot
Figure 8 Market, By Surgery Type, 2014 & 2020 (USD Million)
Figure 9 Market in Anterior Cervical Discectomy and Fusion (ACDF) Surgery, By Product Type, 2015 & 2020 (USD Million)
Figure 10 Market in Anterior Cervical Discectomy and Fusion (ACDF) Surgery, By Geography, 2015 & 2020 (USD Million)
Figure 11 Spine Biologics Market in Transforaminal Lumbar Interbody Fusion (TLIF) Surgery, By Product Type, 2015 & 2020 (USD Million)
Figure 12 Spine Biologics Market in Transforaminal Lumbar Interbody Fusion (TLIF) Surgery, By Geography, 2015 & 2020 (USD Million)
Figure 13 Spine Biologics Market in Anterior Lumbar Interbody Fusion (ALIF) Surgery, By Product Type, 2015 & 2020 (USD Million)
Figure 14 Spine Biologics Market in Anterior Lumbar Interbody Fusion (ALIF) Surgery, By Geography, 2015 & 2020 (USD Million)
Figure 15 Spine Biologics Market in Lateral Lumbar Interbody Fusion (LLIF) Surgery, By Product Type, 2015 & 2020 (USD Million)
Figure 16 Spine Biologics Market in Lateral Lumbar Interbody Fusion (LLIF) Surgery, By Geography, 2015 & 2020 (USD Million)
Figure 17 Spine Biologics Market Value, By Product Type, 2014 & 2020 (USD Million)
Figure 18 Bone Grafts Market Value, By Surgery Type, 2015 & 2020 (USD Million)
Figure 19 Spine Grafts Market Value, By Geography, 2015 & 2020 (USD Million)
Figure 20 Bone Graft Substitutes Market Value, By Product Type, 2014 & 2020 (USD Million)
Figure 21 Synthetic Bone Grafts Market Value, By Surgery Type, 2015 & 2020 (USD Million)
Figure 22 Synthetic Bone Grafts Market Value, By Geography, 2015 & 2020 (USD Million)
Figure 23 Demineralized Bone Matrix (DBM) Market Value, By Surgery Type, 2015 & 2020 (USD Million)
Figure 24 Demineralized Bone Matrix (DBM) Market Value, By Geography, 2015 & 2020 (USD Million)
Figure 25 Bone Morphogenetic Protein (BMP) Market Value, By Surgery Type, 2015 & 2020 (USD Million)
Figure 26 Bone Morphogenetic Protein (BMP) Market Value, By Geography, 2015 & 2020 (USD Million)
Figure 27 Platelet Rich Plasma (PRP) Market Value, By Geography, 2015 & 2020 (USD Million)
Figure 28 Bone Marrow Aspirate Concentrate (BMAC) Therapy Market Value, By Geography, 2015 & 2020 (USD Million)
Figure 29 Spine Biologics Market: Growth Analysis, By Geography, 2014 – 2020 (USD Million)
Figure 30 North America: Market Overview, 2014 & 2020 (%)
Figure 31 North America: Market, By Country, 2015 & 2020 (USD Million)
Figure 32 North America: Market, By Product Type, 2015 & 2020 (USD Million)
Figure 33 North America: Bone Graft Substitutes Market, By Product Type, 2015 & 2020 (USD Million)
Figure 34 North America: Spine Biologics Market, By Surgery Type, 2015 & 2020 (USD Million)
Figure 35 Europe: Spine Biologics Market Overview, 2014 & 2020 (%)
Figure 36 Europe: Spine Biologics Market, By Country, 2015 & 2020 (USD Million)
Figure 37 Europe: Spine Biologics Market, By Product Type, 2015 & 2020 (USD Million)
Figure 38 Europe: Bone Graft Substitutes Market, By Product Type, 2015 & 2020 (USD Million)
Figure 39 Europe: Spine Biologics Market, By Surgery Type, 2015 & 2020 (USD Million)
Figure 40 Asia Pacific: Spine Biologics Market Overview, 2014 & 2020 (%)
Figure 41 Asia Pacific: Spine Biologics Market, By Country, 2015 & 2020 (USD Million)
Figure 42 Asia Pacific: Spine Biologics Market, By Product Type, 2015 & 2020 (USD Million)
Figure 43 Asia Pacific: Bone Graft Substitutes Market, By Product Type, 2015 & 2020 (USD Million)
Figure 44 Asia Pacific: Spine Biologics Market, By Surgery Type, 2015 & 2020 (USD Million)
Figure 45 Spine Biologics Market: Company Share Analysis, 2014 (%)
Figure 46 Zimmer Holding, Inc.: Revenue Mix, 2014 (%)
Figure 47 Johnson & Johnson Ltd.: Business Revenue Mix, 2014 (%)
Figure 48 Medtronic, Inc.: Revenue Mix, 2013 (%)
Figure 49 Nuvasive Inc.: Revenue Mix, 2014 (%)
Figure 50 Stryker Corporation: Revenue Mix, 2014 (%)
Figure 51 Orthofix International N.V.: Business Revenue Mix, 2014 (%)
Figure 52 K2M, Inc.: Geographic Revenue Mix, 2014 (%)
Figure 53 Exactech, Inc.: Revenue Mix, 2014 (%)
Figure 54 Wright Medical Technology, Inc.: Revenue Mix, 2014 (%)

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