Small Fiber Neuropathy - Pipeline Insight, 2021

Publisher Name :
Date: 10-Feb-2021
No. of pages: 60
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DelveInsight's, "Small Fiber Neuropathy - Pipeline Insight, 2021," report provides comprehensive insights about 3+ companies and 3+ pipeline drugs in Small Fiber Neuropathy pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

- Global coverage

Small Fiber Neuropathy Understanding

Small Fiber Neuropathy: Overview

Small fiber neuropathy occurs as a result of damage to the small fibers of the peripheral nervous system are damaged. Small fibers in the skin carries sensory information about pain and temperature. In the organs, these small fibers regulate automatic functions such as heart rate and breathing. Small fiber neuropathy may sometimes be a sign of an underlying health condition, such as diabetes or an autoimmune disease. Most small fiber neuropathies occur in a length-dependent fashion, resulting in loss of function in a stocking distribution in the lower extremities. When the condition is more advanced, a glove-like loss in the upper extremities also may occur. In rare cases, a non-length dependent neuropathy results in symptoms involving the trunk, face, proximal limbs, or other focal areas. Pain in the feet and hands is the most common early symptom of small fiber neuropathy.

"Small Fiber Neuropathy- Pipeline Insight, 2021" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Small Fiber Neuropathy pipeline landscape is provided which includes the disease overview and Small Fiber Neuropathy treatment guidelines. The assessment part of the report embraces, in depth Small Fiber Neuropathy commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Small Fiber Neuropathy collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

- The companies and academics are working to assess challenges and seek opportunities that could influence Small Fiber Neuropathy R&D. The therapies under development are focused on novel approaches to treat/improve Small Fiber Neuropathy.

Small Fiber Neuropathy Emerging Drugs Chapters

This segment of the Small Fiber Neuropathy report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Small Fiber Neuropathy Emerging Drugs

- VX-150: Vertex Pharmaceuticals

Mechanism of Action: Nav1.8 voltage-gated sodium channel inhibitors. The drug is currently in phase 2 of clinical trials for the treatment of pain caused by small fiber neuropathy.

- Vixotrigine (BIIB 074): Biogen

BIIB 074 is a voltage and use -dependent channel blocker. It is a centrally and peripherally acting small molecule. Currently, in phase 2 of clinical trials for the treatment of small fiber neuropathy.

Further product details are provided in the report……..

Small Fiber Neuropathy: Therapeutic Assessment

This segment of the report provides insights about the different Small Fiber Neuropathy drugs segregated based on following parameters that define the scope of the report, such as:

- Major Players in Small Fiber Neuropathy

There are approx. 3+ key companies which are developing the therapies for Small Fiber Neuropathy. The companies which have their Small Fiber Neuropathy drug candidates in the mid to advanced stage, i.e. Phase II include, Biogen and others.

Phases

DelveInsight's report covers around 3+ products under different phases of clinical development like

- Late-stage products (Phase III)

- Mid-stage products (Phase II and Phase I/II)

- Early-stage products (Phase I/II and Phase I) along with the details of

- Pre-clinical and Discovery stage candidates

- Discontinued & Inactive candidates

Route of Administration

Small Fiber Neuropathy pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

- Subcutaneous

- Intravenous

- Oral

- Intramuscular

- Parenteral

- Molecule Type

Products have been categorized under various Molecule types such as

- Small molecules

- Peptide

- Polymer

- Monoclonal antibodies

- Gene Therapy

- Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Small Fiber Neuropathy: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Small Fiber Neuropathy therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Small Fiber Neuropathy drugs.

Small Fiber Neuropathy Report Insights

- Small Fiber Neuropathy Pipeline Analysis

- Therapeutic Assessment

- Unmet Needs

- Impact of Drugs

Small Fiber Neuropathy Report Assessment

- Pipeline Product Profiles

- Therapeutic Assessment

- Pipeline Assessment

- Inactive drugs assessment

- Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

- How many companies are developing Small Fiber Neuropathy drugs?

- How many Small Fiber Neuropathy drugs are developed by each company?

- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Small Fiber Neuropathy?

- What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Small Fiber Neuropathy therapeutics?

- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?

- What are the clinical studies going on for Small Fiber Neuropathy and their status?

- What are the key designations that have been granted to the emerging drugs?

Key Players

- Vertex Pharmaceuticals

- Biogen

Key Products

- VX-150

- BIIB074

Small Fiber Neuropathy - Pipeline Insight, 2021

Table of Contents

Introduction
Executive Summary
Small Fiber Neuropathy: Overview
• Causes
• Mechanism of Action
• Signs and Symptoms
• Diagnosis
• Disease Management
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
• Assessment by Product Type
• Assessment by Stage and Product Type
• Assessment by Route of Administration
• Assessment by Stage and Route of Administration
• Assessment by Molecule Type
• Assessment by Stage and Molecule Type
Small Fiber Neuropathy - DelveInsight's Analytical Perspective
In-depth Commercial Assessment
• Small Fiber Neuropathy companies' collaborations, Licensing, Acquisition -Deal Value Trends
Small Fiber Neuropathy Collaboration Deals
• Company-Company Collaborations (Licensing / Partnering) Analysis
• Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
• Comparative Analysis
Drug name: Company name
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
• Comparative Analysis
BIIB 074: Biogen
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
• Comparative Analysis
Drug name: Company name
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
Small Fiber Neuropathy Key Companies
Small Fiber Neuropathy Key Products
Small Fiber Neuropathy- Unmet Needs
Small Fiber Neuropathy- Market Drivers and Barriers
Small Fiber Neuropathy- Future Perspectives and Conclusion
Small Fiber Neuropathy Analyst Views
Small Fiber Neuropathy Key Companies
Appendix

List of Tables

Table 1 Total Products for Small Fiber Neuropathy
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

List of Figures

Figure 1 Total Products for Small Fiber Neuropathy
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
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