Protein A Resin Market by Product (Agarose-based, Glass/Silica-based, Organic polymer-based), Type (Recombinant Protein A, Natural Protein A), Application (Antibody Purification, Immunoprecipitation), End User & Region - Global Forecasts to 2028

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Date: 05-Apr-2023
No. of pages: 147
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“The protein A resin market is projected to grow at a CAGR of 9.8% during the forecast period (2022–2028).”

The global protein A resin market is projected to reach USD 2.1 billion by 2028 from USD 1.2 billion in 2022, growing at a CAGR of 9.8% during the forecast period. The rise in advantages offered by protein A resin to be used in therapeutics is one of the major factors anticipated to boost market growth in the forecasting years.

“The agarose-based protein A resin segment to hold the largest share of the market in 2022

On the basis of product, the protein A resin market is segmented into agarose-based protein A, glass/silica-based protein A, and organic polymer-based protein A. The agarose-based protein A segment commanded the largest share of the market in 2022, as agarose is the most widely used matrix resin for the attachment of ligands that bind proteins.

“The recombinant protein A resin segment to hold the largest share of the market in 2022

On the basis of type, the protein A resin market is segmented into recombinant and natural protein A resin. The recombinant protein A segment accounted for a larger market share in 2022 and is estimated to register a higher CAGR during the forecast period. The high growth of this segment can be attributed to the increasing technological advancements for the discovery of drugs and antibody purifications.

“The antibody purification segment is projected to register the highest CAGR during the forecast period”

Based on application, the protein A resin market is segmented into antibody purification and immunoprecipitation. The antibody purification application segment dominated the market in 2022 and is expected to register a higher CAGR during the forecast period. The high growth of this segment can primarily be attributed to the increasing use in downstream processing of the antibodies and increasing demand for mAbs for therapeutic as well as research purposes.

“The pharmaceutical & biopharmaceutical companies segment is projected to register the highest CAGR during the forecast period”

The end-user market is segmented into pharmaceutical and biopharmaceutical companies, academic research institutes, and other end users. Pharmaceutical and biopharmaceutical companies accounted for the largest share of the global protein A resin market in 2022. This end-user segment is also estimated to grow at the highest CAGR during the forecast period. This can be attributed to the factors such as increasing use for monoclonal antibodies in the therapeutic areas of different diseases like oncology, tuberculosis, and autoimmune diseases.

“The market in the North America region is expected to hold significant market share for protein A resin in 2022.”

The protein A resin market covers five key geographies—North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. The market in the North America region is expected to hold significant market share for protein A resin in 2022. The growth of the protein A resin market in this region can be attributed to the increasing investments in pharmaceutical R&D and government funding for R&D activities.

A breakdown of the primary participants referred to for this report is provided below:


  • By Company Type: Tier 1–48%, Tier 2–36%, and Tier 3– 16%

  • By Designation: C-level–10%, Director-level–14%, and Others–76%

  • By Region: North America–40%, Europe–32%, Asia Pacific–20%, Latin America–5%, and the Middle East & Africa–3%


he prominent players in the protein A resin market are Danaher Corporation (US), Merck KGaA (Germany), Repligen Corporation (US), Bio-Rad Laboratories, Inc. (US), Thermo Fisher Scientific Inc. (US), and Tosoh Corporation (Japan) among others.

Research Coverage

This report studies the protein A resin market based on product, type, application, end user and region. It also covers the factors affecting market growth, analyzes the various opportunities and challenges in the market, and provides details of the competitive landscape for market leaders. Furthermore, the report analyzes micro markets with respect to their individual growth trends and forecasts the revenue of the market segments with respect to five main regions (and the respective countries in these regions).

Reasons to Buy the Report

The report will help the market leaders/new entrants in this market with information on the closest approximations of the revenue numbers for the overall C4ISR market and the subsegments. This report will help stakeholders understand the competitive landscape and gain more insights to position their businesses better and to plan suitable go-to-market strategies. The report also helps stakeholders understand the pulse of the market and provides them with information on key market drivers, restraints, challenges, and opportunities.

This report provides insights on the following pointers: 


  • Analysis of key drivers (Need for enhanced integrated situational awareness to support decision making, modernization of defense capabilities to address asymmetric warfare threats, Rising Military focus on wireless connectivity and technologies), restraints (High Development and Maintenance costs of C4 System, Vulnerability to cyberattacks. Regulatory obstacles related to technology transfer), opportunities (Increasing need for interoperability between military devices/technologies. Incraesing use of AI to assist in effective decision making, Cloud computing and data storage solutions for C4ISR), and challenges (Inability of existing electronic warfare systems to address diverse threats) influencing the growth of the C4ISR market

  • Product Development/Innovation: Detailed insights on upcoming technologies, research & development activities, and new product & service launches in the C4ISR market

  • Market Development: Comprehensive information about lucrative markets – the report analyses the C4ISR market across varied regions

  • Market Diversification: Exhaustive information about new products & services, untapped geographies, recent developments, and investments in the C4ISR market

  • Competitive Assessment: In-depth assessment of market shares, growth strategies and service offerings of leading players like Lockheed Martin Corporation (US), Raytheon Technologies Corporation (US), Thales (France), BAE Systems Inc. (UK), General Dynamics Corporation (US), and Northrop Grumman (US), among others in the C4ISR market

  • Product Development/Innovation:Detailed insights on the upcoming trends, R&D activities, and product launches in the protein A resin market

  • Market Development:Comprehensive information on lucrative emerging regions

  • Market Diversification:Exhaustive information about new products, growing geographies, and recent developments in the protein A resin market

  • Competitive Assessment: In-depth assessment of market segments, growth strategies, revenue analysis, and products of the leading market players.

Protein A Resin Market by Product (Agarose-based, Glass/Silica-based, Organic polymer-based), Type (Recombinant Protein A, Natural Protein A), Application (Antibody Purification, Immunoprecipitation), End User & Region - Global Forecasts to 2028

Table Of Contents

1 Introduction 18
1.1 Study Objectives 18
1.2 Market Definition 18
1.3 Inclusions And Exclusions 19
Table 1 Protein A Resin Market: Inclusions And Exclusions 19
1.4 Markets Covered 19
Figure 1 Market Segmentation 19
1.4.1 Geographic Segmentation 20
1.5 Years Considered 20
1.6 Currency Considered 20
1.7 Limitations 21
1.8 Stakeholders 21
1.9 Summary Of Changes 21

2 Research Methodology 23
2.1 Research Data 23
2.2 Recession Impact 23
Figure 2 Research Design 24
2.2.1 Secondary Research 25
2.2.2 Primary Research 26
2.2.2.1 Primary Sources 26
2.2.2.2 Key Industry Insights 27
2.2.2.3 Breakdown Of Primaries 27
Figure 3 Breakdown Of Primary Interviews: Supply-Side And Demand-Side Participants 27
Figure 4 Breakdown Of Primary Interviews: By Company Type, Designation, And Region 28
2.3 Research Assumption 28
Figure 5 Research Methodology: Hypothesis Building 29
2.3.1 Bottom-Up Approach 29
2.3.1.1 Approach 1: Company Revenue Estimation Approach 30
Figure 6 Market Size Estimation: Vendor Revenue Mapping Approach 30
Figure 7 Analysis Of Vendor Revenue Mapping 31
2.3.1.2 Approach 2: Customer-Based Market Estimation 31
Figure 8 Protein A Resin Market Size Estimation: Bottom-Up Approach 32
2.3.1.3 Cagr Projection 32
Figure 9 Cagr Projection: Supply-Side Analysis 32
2.4 Data Validation Approach 33
Figure 10 Data Triangulation Methodology 33
2.5 Market Share Assessment 34
2.6 Study Assumptions 34
2.7 Risk Assessment 34
2.7.1 Protein A Resin Market: Risk Assessment 34
2.8 Growth Rate Assumptions 35

3 Executive Summary 36
Figure 11 Protein A Resin Market, By Product, 2022 Vs. 2028 (Usd Million) 36
Figure 12 Protein A Resin Market, By Type, 2022 Vs. 2028 (Usd Million) 37
Figure 13 Protein A Resin Market, By Application, 2022 Vs. 2028 (Usd Million) 37
Figure 14 Protein A Resin Market, By End User, 2022 Vs. 2028 (Usd Million) 38
Figure 15 Geographic Snapshot: Protein A Resin Market 39

4 Premium Insights 40
4.1 Protein A Resin Market Overview 40
Figure 16 Increasing Demand For Pre-Packed Disposable Columns To Drive Market Growth 40
4.2 North America: Protein A Resin Market, By Product, 2022 Vs. 2028 (Usd Million) 41
Figure 17 Agarose-Based Protein A Segment To Dominate North American Market During Forecast Period 41
4.3 Asia Pacific: Protein A Resin Market, By End User, 2022 Vs. 2028 (Usd Million) 41
Figure 18 Pharmaceutical And Biopharmaceutical Companies Segment To Continue To Dominate Asia Pacific Market During Forecast Period 41
4.4 Geographic Snapshot Of Protein A Resin Market 42
Figure 19 China To Witness Highest Growth During Forecast Period 42

5 Market Overview 43
5.1 Introduction 43
5.2 Market Dynamics 43
Figure 20 Protein A Resin Market: Drivers, Restraints, Opportunities, And Challenges 43
5.2.1 Drivers 44
5.2.1.1 Growing Demand For Disposable Pre-Packed Columns 44
Table 2 Advantages Of Pre-Packed Columns 44
5.2.1.2 Increasing Demand For Therapeutic Antibodies 44
5.2.1.3 Increasing Pharmaceutical R&D Spending 45
5.2.1.4 Stringent Regulatory Control In Healthcare Industry 45
5.2.2 Restraints 45
5.2.2.1 High Cost Of Resins 45
5.2.2.2 Dearth Of Skilled Professionals 45
5.2.3 Opportunities 46
5.2.3.1 Increasing Number Of Cmos And Cros 46
5.2.4 Challenges 46
5.2.4.1 Regulatory Restrictions 46
5.2.4.2 Issues Associated With Scaling Up Production Of Protein A Resins 47
5.3 Regulations 47
5.3.1 North America 47
5.3.1.1 Us 47
5.3.1.2 Canada 47
5.3.2 Europe 48
5.3.3 Asia Pacific 48
5.3.4 Latin America 49
5.3.5 Middle East & Africa 49
5.4 Pricing Analysis: Protein A Resin Market 49
5.5 Porter’s Five Forces Analysis 50
Table 3 Protein A Resin Market: Porter’s Five Forces Analysis 50
5.5.1 Threat Of Substitutes 50
5.5.2 Bargaining Power Of Suppliers 51
5.5.3 Bargaining Power Of Buyers 51
5.5.4 Threat Of New Entrants 52
5.5.5 Intensity Of Competitive Rivalry 52

6 Protein A Resin Market, By Product 53
6.1 Introduction 54
Table 4 Protein A Resin Market, By Product, 2020–2028 (Usd Million) 54
6.2 Agarose-Based Protein A 54
6.2.1 Agarose-Based Protein A Segment To Dominate Market 54
Table 5 Agarose-Based Protein A Market, By Region, 2020–2028 (Usd Million) 55
Table 6 North America: Agarose-Based Protein A Market, By Country, 2020–2028 (Usd Million) 55
Table 7 Europe: Agarose-Based Protein A Market, By Country, 2020–2028 (Usd Million) 55
Table 8 Asia Pacific: Agarose-Based Protein A Market, By Country, 2020–2028 (Usd Million) 56
6.3 Glass/Silica-Based Protein A 56
6.3.1 Low Ph Tolerance Of Silica-Based Resins To Limit Their Market Growth 56
Table 9 Glass/Silica-Based Protein A Market, By Region, 2020–2028 (Usd Million) 56
Table 10 North America: Glass/Silica-Based Protein A Market, By Country, 2020–2028 (Usd Million) 57
Table 11 Europe: Glass/Silica-Based Protein A Market, By Country, 2020–2028 (Usd Million) 57
Table 12 Asia Pacific: Glass/Silica-Based Protein A Market, By Country, 2020–2028 (Usd Million) 58
6.4 Organic Polymer-Based Protein A 58
6.4.1 Increasing Popularity Of Organic Polymers To Drive Market Growth 58
Table 13 Organic Polymer-Based Protein A Market, By Region, 2020–2028 (Usd Million) 59
Table 14 North America: Organic Polymer-Based Protein A Market, By Country, 2020–2028 (Usd Million) 59
Table 15 Europe: Organic Polymer-Based Protein A Market, By Country, 2020–2028 (Usd Million) 59
Table 16 Asia Pacific: Organic Polymer-Based Protein A Market, By Country, 2020–2028 (Usd Million) 60

7 Protein A Resin Market, By Type 61
7.1 Introduction 62
Table 17 Protein A Resin Market, By Type, 2020–2028 (Usd Million) 62
7.2 Recombinant Protein A 62
7.2.1 Cost-Efficiency Of Recombinant Proteins To Drive Market Growth 62
Table 18 Recombinant Protein A Market, By Region, 2020–2028 (Usd Million) 63
7.3 Natural Protein A 63
7.3.1 Advantages Of Recombinant Protein A Have Restricted Market Potential Of Natural Protein A 63
Table 19 Natural Protein A Market, By Region, 2020–2028 (Usd Million) 63

8 Protein A Resin Market, By Application 64
8.1 Introduction 65
Table 20 Protein A Resin Market, By Application, 2020–2028 (Usd Million) 65
8.2 Antibody Purification 65
8.2.1 Antibody Purification Segment To Dominate Market During Forecast Period 65
Table 21 Protein A Resin Market For Antibody Purification, By Region, 2020–2028 (Usd Million) 66
8.3 Immunoprecipitation 66
8.3.1 Immunoprecipitation Segment To Grow At Lower Cagr During Forecast Period 66
Table 22 Protein A Resin Market For Immunoprecipitation, By Region, 2020–2028 (Usd Million) 66

9 Protein A Resin Market, By End User 67
9.1 Introduction 68
Table 23 Protein A Resin Market, By End User, 2020–2028 (Usd Million) 68
9.2 Pharmaceutical And Biopharmaceutical Companies 68
9.2.1 Protein A Resins Extensively Used To Produce Biological Drugs 68
Figure 21 Spending On Pharmaceutical Research And Development, 2020–2028 (Usd Billion) 69
Table 24 Protein A Resin Market For Pharmaceutical And Biopharmaceutical Companies, By Region, 2020–2028 (Usd Million) 69
9.3 Academic Research Institutes 70
9.3.1 Increasing R&D In Drug Discovery To Drive Use Of Protein A Resins 70
Table 25 Protein A Resin Market For Academic Research Institutes, By Region, 2020–2028 (Usd Million) 70
9.4 Other End Users 70
Table 26 Protein A Resin Market For Other End Users, By Region, 2020–2028 (Usd Million) 71

10 Protein A Resin Market, By Region 72
10.1 Introduction 73
Table 27 Protein A Resin Market, By Region, 2020–2028 (Usd Million) 73
10.2 North America 74
Figure 22 North America: Protein A Resin Market Snapshot 74
Table 28 North America: Protein A Resin Market, By Country, 2020–2028 (Usd Million) 75
Table 29 North America: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 75
Table 30 North America: Protein A Resin Market, By Type, 2020–2028 (Usd Million) 75
Table 31 North America: Protein A Resin Market, By Application, 2020–2028 (Usd Million) 76
Table 32 North America: Protein A Resin Market, By End User, 2020–2028 (Usd Million) 76
10.2.1 Us 76
10.2.1.1 Increasing R&D Investments In Pharmaceutical Industry To Propel Market Growth 76
Table 33 Us: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 77
10.2.2 Canada 77
10.2.2.1 Government Initiatives Focused On Boosting Pharmaceutical Industry To Drive Market Growth 77
Table 34 Canada: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 77
10.3 Europe 78
Table 35 Europe: Protein A Resin Market, By Country, 2020–2028 (Usd Million) 78
Table 36 Europe: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 78
Table 37 Europe: Protein A Resin Market, By Type, 2020–2028 (Usd Million) 79
Table 38 Europe: Protein A Resin Market, By Application, 2020–2028 (Usd Million) 79
Table 39 Europe: Protein A Resin Market, By End User, 2020–2028 (Usd Million) 79
10.3.1 Germany 80
10.3.1.1 Flourishing Biotechnology Industry To Drive Market Growth 80
Table 40 Germany: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 80
10.3.2 Uk 80
10.3.2.1 Favorable R&D Scenario To Support Market Growth 80
Table 41 Uk: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 81
10.3.3 France 81
10.3.3.1 Favorable Healthcare Scenario To Boost Market Growth 81
Table 42 France: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 81
10.3.4 Italy 82
10.3.4.1 Well-Established Pharmaceutical Industry To Spur Demand For Protein A Resins 82
Table 43 Italy: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 82
10.3.5 Spain 82
10.3.5.1 Presence Of Large Number Of Biotech R&D Service Providers To Support Market Growth 82
Table 44 Spain: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 83
10.3.6 Rest Of Europe 83
Table 45 Rest Of Europe: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 84
10.4 Asia Pacific 85
Figure 23 Asia Pacific: Protein A Resin Market Snapshot 85
Table 46 Asia Pacific: Protein A Resin Market, By Country, 2020–2028 (Usd Million) 86
Table 47 Asia Pacific: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 86
Table 48 Asia Pacific: Protein A Resin Market, By Type, 2020–2028 (Usd Million) 86
Table 49 Asia Pacific: Protein A Resin Market, By Application, 2020–2028 (Usd Million) 87
Table 50 Asia Pacific: Protein A Resin Market, By End User, 2020–2028 (Usd Million) 87
10.4.1 Japan 87
10.4.1.1 Increasing Demand For Generic Drugs And Monoclonal Antibody Biosimilars To Drive Resin Consumption 87
Table 51 Japan: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 88
10.4.2 China 88
10.4.2.1 Increasing Pharmaceutical R&D Spending To Drive Market Growth 88
Table 52 China: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 88
10.4.3 India 89
10.4.3.1 Growth Of Pharma And Biotech Industries To Drive Demand For Protein A Resins 89
Table 53 India: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 89
10.4.4 Australia 89
10.4.4.1 Increasing Demand For Protein-Based Therapeutics For Treatment Of Infectious Diseases To Drive Growth 89
Table 54 Australia: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 90
10.4.5 South Korea 90
10.4.5.1 Developments In Biopharmaceutical Sector To Drive Market Growth 90
Table 55 South Korea: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 90
10.4.6 Rest Of Asia Pacific 91
Table 56 Rest Of Asia Pacific: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 91
10.5 Rest Of The World 91
Table 57 Row: Protein A Resin Market, By Product, 2020–2028 (Usd Million) 92
Table 58 Row: Protein A Resin Market, By Type, 2020–2028 (Usd Million) 92
Table 59 Row: Protein A Resin Market, By Application, 2020–2028 (Usd Million) 92
Table 60 Row: Protein A Resin Market, By End User, 2020–2028 (Usd Million) 93

11 Competitive Landscape 94
11.1 Overview 94
11.2 Market Share Analysis 94
Figure 24 Protein A Resin Market Share Analysis (2021) 94
11.3 Competitive Leadership Mapping 95
11.3.1 Stars 95
11.3.2 Emerging Leaders 95
11.3.3 Pervasive Players 95
11.3.4 Participants 95
Figure 25 Protein A Resin Market: Competitive Leadership Mapping (2022) 96
11.4 Competitive Scenario 97
11.4.1 Product Launches 97
Table 61 Protein A Resin Market: Product Launches, January 2020 To February 2023 97
11.4.2 Deals 97
Table 62 Protein A Resin Market: Deals, January 2020 To February 2023 97
11.4.3 Other Developments 98
Table 63 Protein A Resin Market: Other Developments, January 2020 To February 2023 98

12 Company Profiles 99
12.1 Key Players 99
(Business Overview, Products/Services/Solutions Offered, Mnm View, Key Strengths And Right To Win, Strategic Choices Made, Weaknesses And Competitive Threats, Recent Developments)*
12.1.1 Danaher Corporation 99
Table 64 Danaher Corporation: Company Overview 99
Figure 26 Danaher Corporation: Company Snapshot (2021) 100
12.1.2 Thermo Fisher Scientific 103
Table 65 Thermo Fisher Scientific: Company Overview 103
Figure 27 Thermo Fisher Scientific: Company Snapshot (2022) 104
12.1.3 Merck Kgaa 107
Table 66 Merck Kgaa: Company Overview 107
Figure 28 Merck Kgaa: Company Snapshot (2022) 108
12.1.4 Repligen Corporation 110
Table 67 Repligen Corporation: Company Overview 110
Figure 29 Repligen Corporation: Company Snapshot (2022) 110
12.1.5 Tosoh Bioscience Llc 113
Table 68 Tosoh Bioscience Llc: Company Overview 113
Figure 30 Tosoh Bioscience Llc: Company Snapshot (2021) 114
12.1.6 Agilent Technologies, Inc. 116
Table 69 Agilent Technologies, Inc.: Company Overview 116
Figure 31 Agilent Technologies Inc.: Company Snapshot (2022) 117
12.1.7 Purolite 120
Table 70 Purolite: Company Overview 120
12.1.8 Perkinelmer Inc. 122
Table 71 Perkinelmer Inc.: Company Overview 122
Figure 32 Perkinelmer Inc.: Company Snapshot (2022) 123
12.1.9 Novasep Holding Sas 124
Table 72 Novasep Holding Sas: Company Overview 124
12.1.10 Genscript 125
Table 73 Genscript: Company Overview 125
Figure 33 Genscript: Company Snapshot (2021) 126
12.1.11 Bio-Rad Laboratories, Inc. 127
Table 74 Bio-Rad Laboratories, Inc.: Company Overview 127
Figure 34 Bio-Rad Laboratories, Inc.: Company Snapshot (2022) 128
12.1.12 Kaneka Corporation 130
Table 75 Kaneka Corporation: Company Overview 130
Figure 35 Kaneka Corporation: Company Snapshot (2021) 130
12.1.13 Orochem Technologies Inc. 132
Table 76 Orochem Technologies Inc.: Company Overview 132
12.1.14 Abcam Plc 133
Table 77 Abcam Plc.: Company Overview 133
12.1.15 Agarose Bead Technologies 134
Table 78 Agarose Bead Technologies: Company Overview 134
*Business Overview, Products/Services/Solutions Offered, Mnm View, Key Strengths And Right To Win, Strategic Choices Made, Weaknesses And Competitive Threats, Recent Developments Might Not Be Captured In Case Of Unlisted Companies.
12.2 Other Companies 135
12.2.1 Avantor, Inc. 135
12.2.2 Jsr Lifesciences, Llc 135
12.2.3 Bio-Works 136
12.2.4 Takara Bio Inc. 136
12.2.5 Generon 137
12.2.6 Geno Technology Inc. 137
12.2.7 Jnc Corporation 138
12.2.8 Promega Corporation 138
12.2.9 Suzhou Nanomicro Technology Co., Ltd. 139
12.2.10 Transgen Biotech Co., Ltd. 139

13 Appendix 140
13.1 Discussion Guide 140
13.2 Knowledgestore: Marketsandmarkets’ Subscription Portal 143
13.3 Customization Options 145
13.4 Related Reports 145
13.5 Author Details 147

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