Primary Hyperoxaluria - Pipeline Review, H1 2018

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Date: 27-Feb-2018
No. of pages: 44
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Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Primary Hyperoxaluria - Pipeline Review, H1 2018, provides an overview of the Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) pipeline landscape.

Primary hyperoxaluria is a rare condition characterized by recurrent kidney and bladder stones. It results from the overproduction of a substance called oxalate. Symptoms include blood in the urine, pain when urinating, fever, sudden abdominal pain and frequent urge to urinate. Treatment includes Oral preparations of phosphates and diuretics.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Primary Hyperoxaluria - Pipeline Review, H1 2018, provides comprehensive information on the therapeutics under development for Primary Hyperoxaluria (Genito Urinary System And Sex Hormones), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) pipeline guide also reviews of key players involved in therapeutic development for Primary Hyperoxaluria and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I and Discovery stages are 1, 1, 2 and 1 respectively.

Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note : Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Primary Hyperoxaluria (Genito Urinary System And Sex Hormones).

  • The pipeline guide reviews pipeline therapeutics for Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) by companies and universities/research institutes based on information derived from company and industry-specific sources.

  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.

  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.

  • The pipeline guide reviews key companies involved in Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) therapeutics and enlists all their major and minor projects.

  • The pipeline guide evaluates Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.

  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.

  • The pipeline guide reviews latest news related to pipeline therapeutics for Primary Hyperoxaluria (Genito Urinary System And Sex Hormones)

Reasons to buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.

  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.

  • Find and recognize significant and varied types of therapeutics under development for Primary Hyperoxaluria (Genito Urinary System And Sex Hormones).

  • Classify potential new clients or partners in the target demographic.

  • Develop tactical initiatives by understanding the focus areas of leading companies.

  • Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.

  • Formulate corrective measures for pipeline projects by understanding Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) pipeline depth and focus of Indication therapeutics.

  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.

  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Primary Hyperoxaluria - Pipeline Review, H1 2018

Table of Contents

List of Tables
List of Figures
Introduction
Global Markets Direct Report Coverage
Primary Hyperoxaluria - Overview
Primary Hyperoxaluria - Therapeutics Development
Pipeline Overview
Pipeline by Companies
Products under Development by Companies
Primary Hyperoxaluria - Therapeutics Assessment
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Primary Hyperoxaluria - Companies Involved in Therapeutics Development
Allena Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Dicerna Pharmaceuticals Inc
Intellia Therapeutics Inc
OxThera AB
Primary Hyperoxaluria - Drug Profiles
ALLN-177 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
ALN-GO1 - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
DCR-PHXC - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Oligonucleotides for Primary Hyperoxaluria - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Oxabact - Drug Profile
Product Description
Mechanism Of Action
R&D Progress
Primary Hyperoxaluria - Dormant Projects
Primary Hyperoxaluria - Discontinued Products
Primary Hyperoxaluria - Product Development Milestones
Featured News & Press Releases
Dec 07, 2017: Dicerna Announces First Human Dosed in Phase 1 Clinical Trial of DCR-PHXC for Treatment of All Forms of Primary Hyperoxaluria
Nov 03, 2017: Alnylam Reports Positive Preliminary Results from Ongoing Phase 1/2 Study of Lumasiran (ALN-GO1) in Patients with Primary Hyperoxaluria Type 1
Oct 16, 2017: Dicerna Files Clinical Trial Application for DCR-PHXC, the Company's Most Advanced GalXC Product Candidate, for Phase 1 Study in Primary Hyperoxaluria
Jul 27, 2017: European Commission Grants Orphan Drug Designation to Allena Pharmaceuticals Investigational Therapy for the Treatment of Primary Hyperoxaluria
Jul 17, 2017: Dicerna Expands Lead GalXC Development Program to Encompass All Forms of Primary Hyperoxaluria (PH) and Reveals New Therapeutic Target for DCR-PHXC
Jul 13, 2017: FDA Grants Orphan Drug Designation to Allena Pharmaceuticals' Investigational Therapy for the Treatment of Primary Hyperoxaluria
Jul 05, 2017: Matthew Gantz Appointed CEO of OxThera
Sep 24, 2016: Alnylam Reports Positive Initial Results from Ongoing Phase 1/2 Study of ALN-GO1, an Investigational RNAi Therapeutic for the Treatment of Primary Hyperoxaluria Type 1
Mar 09, 2016: Alnylam Initiates Phase 1/2 Clinical Trial for ALN-GO1, an Investigational RNAi Therapeutic for the Treatment of Primary Hyperoxaluria Type 1 (PH1)
Dec 21, 2015: Alnylam Files Clinical Trial Application for ALN-GO1, an Investigational RNAi Therapeutic for the Treatment of Primary Hyperoxaluria Type 1 (PH1)
Sep 08, 2015: Alnylam Accelerates Development of ALN-GO1, a Subcutaneously Administered Investigational RNAi Therapeutic for the Treatment of Primary Hyperoxaluria Type 1
Oct 14, 2014: Alnylam Pharmaceuticals Presents Pre-Clinical Data From New Program, ALN-GO1, At 10th Oligonucleotide Therapeutics Society Meeting
Jan 08, 2014: OxThera Initiates Clinical Trial in Primary Hyperoxaluria
Jun 04, 2013: OxThera Strengthens Patent Portfolio For Orphan Disease
Apr 03, 2008: Pivotal study is being conducted with Oxabact for the treatment of Primary Hyperoxaluria
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer

List of Tables

Number of Products under Development for Primary Hyperoxaluria, H1 2018
Number of Products under Development by Companies, H1 2018
Products under Development by Companies, H1 2018
Number of Products by Stage and Target, H1 2018
Number of Products by Stage and Mechanism of Action, H1 2018
Number of Products by Stage and Route of Administration, H1 2018
Number of Products by Stage and Molecule Type, H1 2018
Primary Hyperoxaluria - Pipeline by Allena Pharmaceuticals Inc, H1 2018
Primary Hyperoxaluria - Pipeline by Alnylam Pharmaceuticals Inc, H1 2018
Primary Hyperoxaluria - Pipeline by Dicerna Pharmaceuticals Inc, H1 2018
Primary Hyperoxaluria - Pipeline by Intellia Therapeutics Inc, H1 2018
Primary Hyperoxaluria - Pipeline by OxThera AB, H1 2018
Primary Hyperoxaluria - Dormant Projects, H1 2018
Primary Hyperoxaluria - Discontinued Products, H1 2018

List of Figures

Number of Products under Development for Primary Hyperoxaluria, H1 2018
Number of Products under Development by Companies, H1 2018
Number of Products by Stage and Targets, H1 2018
Number of Products by Stage and Mechanism of Actions, H1 2018
Number of Products by Routes of Administration, H1 2018
Number of Products by Stage and Routes of Administration, H1 2018
Number of Products by Molecule Types, H1 2018
Number of Products by Stage and Molecule Types, H1 2018
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