Polymerase Chain Reaction (PCR) Technologies and Global Markets

Publisher Name :
Date: 24-Aug-2021
No. of pages: 136

Report Scope:

This report examines the market potential of PCR technology. It offers a detailed analysis of the competitive environment, regulatory scenario, technological advances, drivers and restraints, and opportunity and trends in market growth. The report also covers market projections to 2026 and market rankings for key players. The report discusses the market share of PCR technologies based on type of product, technology and application.

This report segments the global market by four geographical regions: North America, Europe, Asia-Pacific and Rest of the World (RoW). For the purpose of this report, North America includes the U.S., Canada and Mexico; the European region includes Germany, U.K., France and Rest of Europe; the Asia-Pacific region includes China, India, Japan, and Rest of Asia-Pacific; and RoW includes the Middle East, Africa and South America. For market estimates, data is provided for the year 2020 as the base year, 2019 as the historical year and forecasts are through year-end 2026.

Report Includes:

- 70 data tables and 15 additional tables

- An updated review of the global market for polymerase chain reaction (PCR) technologies

- Analyses of the global market trends, with data from 2019-2020, estimates for 2021 and projections of compound annual growth rates (CAGRs) through 2026

- Discussion of major factors driving the growth of the PCR market, industry structure, regulatory scenario, and penetration of technologies in molecular diagnosis of infectious diseases

- Estimation of market size and revenue sales forecast for PCR products, and corresponding market share analysis by product, technology type, application, and geographic region

- Impact of the COVID-19 on the market for PCR technology, R&D efforts and the need to reinvent medical ventilators, current status and impact on Medtech

- Highlights of emerging technology trends, opportunities and gaps estimating current and future demand for PCR technology in clinical diagnostics

- Identification of the companies that are best positioned to meet this demand because of their proprietary technologies, strategic alliances or other advantages

- Competitive landscape of the major players operating in the global market, their competitive environment and product portfolio analysis

- Profile descriptions of the leading industry players including Abbott Laboratories, Agilent Technologies Inc., Becton, Dickinson and Co., Bio-Rad Laboratories Inc., and Thermo Fisher Scientific

Summary:

The molecular diagnostic industry is an integral part of the healthcare industry. It is continuously evolving with the advent of novel technologies such as polymerase chain reaction (PCR), deoxyribonucleic acid (DNA) sequencing and next-generation sequencing (NGS). PCR technology has vast potential in the fields of proteomics and genomics and has revolutionized the molecular and functional genomics sector. PCR technology includes real-time PCR, reverse transcriptase PCR, hot start and touchdown PCR, and multiplex PCR.

Technology drivers of the PCR market include advances in instrumentation, reagents and PCR techniques, and increasing R&D. Health- and healthcare-related drivers include increasingly sedentary lifestyles, the growing incidence of diseases such as diabetes, cancer and cardiovascular, and the increasing percentage of baby-boomers. Use of PCR is increasing beyond the conventional markets. Research labs and institutions are using PCR for various research activities for pharmaceutical companies, biotech and drug/product discovery companies, forensic labs and clinical diagnostic labs.

The global PCR product market is expected to grow at a compound average growth rate (CAGR) of REDACTED through 2026. Reagents and consumables is the largest market segment in terms of revenues. The availability of ready-made mixes and reagents has spurred the growth of the reagent market. The instruments segment, which includes real-time PCR instruments and thermal cycles, is another high-growth area. Real-time PCR technology has opened up the arena of PCR applications ranging from diagnosis of infectious diseases to DNA fingerprinting in forensic science. The number of companies entering the PCR reagent business is on the rise, with most of these new entrants being small local companies, but to meet the market demand for new products and reagents, many of these companies must enter into partnerships or collaborations with leading and larger market players, especially for product development and distribution.

Leading companies in this market include F. Hoffmann-La Roche Ltd., Abbott Laboratories, Agilent Technologies, Bio-Rad Laboratories Inc., Thermo Fisher Scientific Inc., Qiagen N.V., Promega Corp. and Merck KGaA (Sigma-Aldrich).

Polymerase Chain Reaction (PCR) Technologies and Global Markets

Table of Contents

Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing this Study
Scope of Report
What's New in this Update
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

Chapter 2 Summary and Highlights
Highlights of the PCR Market

Chapter 3 Background and Technology Overview
Evolution of PCR
Principles of PCR
Instruments and Components of PCR
Instruments
Target DNA
Primers
Enzyme and Enzyme Concentration
Buffers
Magnesium Concentration
Deoxyribonucleoside Triphosphates
Types of PCR
Reverse Transcription PCR
Nested PCR
Hot Start and Touchdown PCR
Inverse PCR
Multiplex PCR
Quantitative PCR
Traditional vs. Real-Time PCR
Design of Primer for PCR
Primer Selection
Primer Length
Melting Temperature
Specificity
G/C Content
3' End Sequence
PCR Quantification Methods
Absolute Quantification
Relative Quantification
Components of Quantitative PCR
DNA Binding Dyes
Probes in qPCR
Controls for qPCR Experiments

Chapter 4 COVID-19 and R&D
Potential Targets for COVID-19 Drug Development
Basigin (CD147)
C-C Chemokine Receptor Type 5 (CCR5)
Envelope Protein (E) (SARS-CoV-2; COVID-19)
Epithelial Sodium Channel (ENaC)
Histamine N-Methyltransferase (HMT)
Interleukin-6 Receptor Subunit a (IL-6RA)
Membrane Glycoprotein (M) (SARS-CoV-2; COVID-19)
Nucleocapsid (N) (SARS-CoV-2; COVID-19)
R&D on COVID-19
COVID-19 Clinical Trial Landscape

Chapter 5 Regulatory Structure of the COVID-19 Diagnostics Industry
Coronavirus Treatment Acceleration Program (CTAP)
Clinical Trials being Conducted during COVID-19 Pandemic
Response to Drug Shortages
National Regulatory Agencies for Ongoing Clinical Trials
U.S. FDA
Medicines and Healthcare Products Regulatory Agency (U.K.)
European Medicines Agency
COVID-19 Testing

Chapter 6 Polymerase Chain Reaction: Market Dynamics
Market Dynamics
Market Drivers
Market Restraints
Market Opportunities

Chapter 7 Impact of COVID-19 Pandemic
Outbreak
Progression of COVID-19
Incubation Period
Epidemiology
Collaboration Between Organizations and Governments
Spread of Disease
Current Status and Impact on Medical Technology
Elective and Noncritical Procedures
Shift in Manufacturing
Delays of Clinical Trials
Supply Chain Disruptions
Medical Tourism

Chapter 8 Market Breakdown by Product Type
Global Market for PCR, by Product Type
Market Size and Forecast
PCR Instruments
Market Size and Forecast
Market Analysis
PCR Reagents and Consumables
Market Size and Forecast
Market Analysis
PCR Software
Market Size and Forecast
Market Analysis
PCR Services
Market Size and Forecast
Market Analysis

Chapter 9 Market Breakdown by Technology
Global Market for PCR, by Technology
Market Size and Forecast
Real-Time PCR
Market Size and Forecast
Market Analysis
Reverse Transcriptase PCR
Market Size and Forecast
Market Analysis
Inverse and Standard PCR
Market Size and Forecast
Market Analysis
Assembly and Nested PCR
Market Size and Forecast
Market Analysis
Hot Start and Touchdown PCR
Market Size and Forecast
Market Analysis
Multiplex PCR and Other PCR
Market Size and Forecast
Market Analysis

Chapter 10 Market Breakdown by Application
Global Market for PCR Technology, by Application
Research Applications
Market Size and Forecast
Market Analysis
Clinical Applications
Market Size and Forecast
Market Analysis
Other PCR Applications
Market Size and Forecast
Market Analysis

Chapter 11 Market Breakdown by Region
Global Market for PCR Technology, by Region
North America
U.S.
Canada
Mexico
Europe
Germany
U.K.
France
Rest of Europe
Asia-Pacific
Japan
China
India
Rest of Asia-Pacific
Rest of the World

Chapter 12 Competitive Landscape
Global Company Shares

Chapter 13 Company Profiles
ABBOTT LABORATORIES
BECTON, DICKINSON AND CO.
BIO-RAD LABORATORIES INC.
F. HOFFMANN-LA ROCHE LTD.
QIAGEN NV
THERMO FISHER SCIENTIFIC INC.
AGILENT TECHNOLOGIES INC.
BIOFIRE DIAGNOSTICS LLC
BIONEER CORP.
EPPENDORF AG

Chapter 14 Appendix: List of Abbreviations

List of Tables

Summary Table A : Global Market for PCR Technology, by Product Type, Through 2026
Summary Table B : Global Market for PCR Technology, by Technology, Through 2026
Summary Table C : Global Market for PCR Technology, by Application, Through 2026
Table 1 : Traditional vs. Real-Time PCR
Table 2 : Advantages and Disadvantages of Dye-Based Detection
Table 3 : COVID-19 Therapeutic Interventions in Development, by Biopharmaceutical Company Collaborations
Table 4 : COVID-19 Therapeutics in Development, by Biopharmaceutical Company Collaboration
Table 5 : COVID-19 Vaccines in Development, by Biopharmaceutical Companies Collaboration
Table 6 : COVID-19 Vaccines in Development, by Biopharmaceutical Company Collaboration
Table 7 : Number of Clinical Trials on COVID-19, by Country
Table 8 : Distribution of COVID-19 Clinical Symptoms
Table 9 : Number of COVID-19 Confirmed Cases and Deaths, by Region, July 21, 2021
Table 10 : Distribution of COVID-19 Clinical Symptoms
Table 11 : Global Market for PCR Technology, by Product, Through 2026
Table 12 : Global Market for PCR Instruments, by Type, Through 2026
Table 13 : Global Market for PCR Instruments, by Region, Through 2026
Table 14 : North American Market for PCR Instruments, by Country, Through 2026
Table 15 : European Market for PCR Instruments, by Country, Through 2026
Table 16 : Asia-Pacific Market for PCR Instruments, by Country, Through 2026
Table 17 : Global Market for PCR Reagents and Consumables, by Type, Through 2026
Table 18 : Global Market for PCR Reagents and Consumables, by Region, Through 2026
Table 19 : North American Market for PCR Reagents and Consumables, by Country, Through 2026
Table 20 : European Market for PCR Reagents and Consumables, by Country, Through 2026
Table 21 : Asia-Pacific Market for PCR Reagents and Consumables, by Country, Through 2026
Table 22 : Global Market for PCR Software, by Type, Through 2026
Table 23 : Global Market for PCR Software, by Region, Through 2026
Table 24 : North American Market for PCR Software, by Country, Through 2026
Table 25 : European Market for PCR Software, by Country, Through 2026
Table 26 : Asia-Pacific Market for PCR Software, by Country, Through 2026
Table 27 : Global Market for PCR Services, by Region, Through 2026
Table 28 : North American Market for PCR Services, by Country, Through 2026
Table 29 : European Market for PCR Services, by Country, Through 2026
Table 30 : Asia-Pacific Market for PCR Services, by Country, Through 2026
Table 31 : Global Market for Real-time PCR, by Region, Through 2026
Table 32 : North American Market for Real-time PCR, by Country, Through 2026
Table 33 : European Market for Real-time PCR, by Country, Through 2026
Table 34 : Asia-Pacific Market for Real-time PCR, by Country, Through 2026
Table 35 : Global Market for Reverse Transcriptase PCR, by Region, Through 2026
Table 36 : North American Market for Reverse Transcriptase PCR, by Country, Through 2026
Table 37 : European Market for Reverse Transcriptase PCR, by Country, Through 2026
Table 38 : Asia-Pacific Market for Reverse Transcriptase PCR, by Country, Through 2026
Table 39 : Global Market for Inverse and Standard PCR, by Region, Through 2026
Table 40 : North American Market for Inverse and Standard PCR, by Country, Through 2026
Table 41 : European Market for Inverse and Standard PCR, by Country, Through 2026
Table 42 : Asia-Pacific Market for Inverse and Standard PCR, by Country, Through 2026
Table 43 : Global Market for Assembly and Nested PCR, by Region, Through 2026
Table 44 : North American Market for Assembly and Nested PCR, by Country, Through 2026
Table 45 : European Market for Assembly and Nested PCR, by Country, Through 2026
Table 46 : Asia-Pacific Market for Assembly and Nested PCR, by Country, Through 2026
Table 47 : Global Market for Hot Start and Touchdown PCR, by Region, Through 2026
Table 48 : North American Market for Hot Start and Touchdown PCR, by Country, Through 2026
Table 49 : European Market for Hot Start and Touchdown PCR, by Country, Through 2026
Table 50 : Asia-Pacific Market for Hot Start and Touchdown PCR, by Country, Through 2026
Table 51 : Global Market for Multiplex and Other PCR, by Region, Through 2026
Table 52 : North American Market for Multiplex and Other PCR, by Country, Through 2026
Table 53 : European Market for Multiplex and Other PCR, by Country, Through 2026
Table 54 : Asia-Pacific Market for Multiplex and Other PCR, by Country, Through 2026
Table 55 : Global Market for PCR Technology, by Application, Through 2026
Table 56 : Global Market for Research Applications, by Region, Through 2026
Table 57 : North American Market for Research Applications, by Country, Through 2026
Table 58 : European Market for Research Applications, by Country, Through 2026
Table 59 : Asia-Pacific Market for Research Applications, by Country, Through 2026
Table 60 : Global Market for Clinical Applications, by Region, Through 2026
Table 61 : North American Market for Clinical Applications, by Country, Through 2026
Table 62 : European Market for Clinical Applications, by Country, Through 2026
Table 63 : Asia-Pacific Market for Clinical Applications, by Country, Through 2026
Table 64 : Global Market for Other PCR Applications, by Region, Through 2026
Table 65 : North American Market for Other PCR Applications, by Country, Through 2026
Table 66 : European Market for Other PCR Applications, by Country, Through 2026
Table 67 : Asia-Pacific Market for Other PCR Applications, by Country, Through 2026
Table 68 : Global Market for PCR Technology, by Region, Through 2026
Table 69 : North American Market for PCR Technology, by Country, Through 2026
Table 70 : European Market for PCR Technology, by Country, Through 2026
Table 71 : Asia-Pacific Market for PCR Technology, by Country, Through 2026
Table 72 : Global Market Shares of PCR Instruments, by Company, 2020
Table 73 : Global Market Shares of PCR Reagents and Consumables, by Company, 2020
Table 74 : Global Market Shares of PCR Software, by Company, 2020
Table 75 : Abbott: Financials, 2016-2020
Table 76 : Abbott: Product Portfolio, by Business Segment
Table 77 : Becton, Dickinson and Co.: Product Portfolio
Table 78 : Bio-Rad Laboratories: PCR Tools
Table 79 : F. Hoffmann-La Roche Ltd.: Product Portfolio
Table 80 : F. Hoffmann-La Roche Ltd.: Recent Developments, 2020 and 2021
Table 81 : Qiagen NV: Financials, 2018-2020
Table 82 : Qiagen NV: Products and Services
Table 83 : Thermo Fisher Scientific: Product Portfolio
Table 84 : Abbreviations Used in the PCR Technology Industry

List of Figures

Summary Figure A : Global Market for PCR Technology, by Product Type, 2019-2026
Summary Figure B : Global Market for PCR Technology, by Technology, 2019-2026
Summary Figure C : Global Market for PCR Technology, by Application, 2019-2026
Figure 1 : Global Market Shares of PCR Technology, by Product, 2020
Figure 2 : Global Market for PCR Instruments, 2019-2026
Figure 3 : Global Market for PCR Reagents and Consumables, 2019-2026
Figure 4 : Global Market for PCR Software, 2019-2026
Figure 5 : Global Market for PCR Services, 2019-2026
Figure 6 : Global Market Shares of PCR, by Technology, 2020
Figure 7 : Global Market Shares of PCR Technology, by Application, 2020
Figure 8 : Global Market Shares of PCR Technology, by Region, 2019
Figure 9 : North American Market Shares of PCR Technology, by Country, 2020
Figure 10 : Number of COVID-19 Cases, by U.S. State
Figure 11 : European Market Shares of PCR Technology, by Country, 2020
Figure 12 : Asia-Pacific Market Shares of PCR Technology, by Country, 2020
Figure 13 : Abbott: Revenue Share, by Country, 2020
Figure 14 : Abbott: Revenue Share, by Business Segments, 2020
Figure 15 : Becton, Dickinson and Co.: Annual Revenue, 2019 and 2020
Figure 16 : Becton, Dickinson and Co.: Revenue Share, by Business Unit, 2020
Figure 17 : Bio-Rad Laboratories: Annual Revenue, 2019 and 2020
Figure 18 : Bio-Rad Laboratories: Revenue Share, by Business Segment, 2020
Figure 19 : Bio-Rad Laboratories: Revenue Share, by Region, 2020
Figure 20 : F. Hoffmann-La Roche Ltd.: Annual Revenue, 2018-2020
Figure 21 : F. Hoffmann-La Roche Ltd.: Revenue Share, by Segment, 2020
Figure 22 : Thermo Fisher Scientific: Annual Revenue, 2019 and 2020
Figure 23 : Thermo Fisher Scientific: Revenue Share, by Product Category, 2020
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