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Chronic Pulmonary Infections - Pipeline Insight, 2021

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Date: 10-Feb-2021
No. of pages: 60
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DelveInsight's, "Chronic Pulmonary Infections - Pipeline Insight, 2021," report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Chronic Pulmonary Infections pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

- Global coverage

Chronic Pulmonary Infections Understanding

Chronic Pulmonary Infections: Overview

Lung infections are very common and are caused by viruses, bacteria and fungal organisms. Chronic lung (or pulmonary) infections affect the lower respiratory tract and can be very debilitating. The most common causes are from chronic obstructive pulmonary disease (COPD), cystic fibrosis, and bronchiectasis, all of which involve inability to clear secretions. The most common symptom of a chronic pulmonary infection is a persistent, severe cough. Sputum culture is performed to identity the infectious agent, and sensitivity testing of this organism can demonstrate any antibiotic resistances that have developed from previous antibiotic exposures. Pulmonary function testing is performed to evaluate the degree of lung compromise with functional testing such as spirometry.

"Chronic Pulmonary Infections- Pipeline Insight, 2021" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Chronic Pulmonary Infections pipeline landscape is provided which includes the disease overview and Chronic Pulmonary Infections treatment guidelines. The assessment part of the report embraces, in depth Chronic Pulmonary Infections commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Chronic Pulmonary Infections collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

- The companies and academics are working to assess challenges and seek opportunities that could influence Chronic Pulmonary Infections R&D. The therapies under development are focused on novel approaches to treat/improve Chronic Pulmonary Infections.

Chronic Pulmonary Infections Emerging Drugs Chapters

This segment of the Chronic Pulmonary Infections report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Chronic Pulmonary Infections Emerging Drugs

- AP-PA02: Armata Pharmaceuticals

AP-PA02 is a therapeutic phage cocktail that targets the pathogen P. aeruginosa, to treat serious respiratory infections, with an initial emphasis on cystic fibrosis (CF) patients. AP-PA02 is comprised of a cocktail of complementary P. aeruginosa phages that offer improved host range, increased potency, and aid in preventing the development of resistance. AP-PA02 demonstrates broad coverage against relevant clinical isolates. Armata Pharmaceuticals plans to initiate the multiple ascending dose cohort of the phase Ib/IIa SWARM-P.a. trial for Pseudomonal infections, in 2021

- Interferon Beta-1A inhalation (SNG-001): Synairgen

SNG001 boosts antiviral responses in the lungs, has a beneficial effect on lung function and, in more difficult to treat patients, improves asthma control during cold infections. On 8 September 2020, Synairgen announced positive data from the interim analysis of its Phase II clinical trial of inhaled SNG001 in COPD patients with a confirmed respiratory viral infection.

Further product details are provided in the report……..

Chronic Pulmonary Infections: Therapeutic Assessment

This segment of the report provides insights about the different Chronic Pulmonary Infections drugs segregated based on following parameters that define the scope of the report, such as:

- Major Players in Chronic Pulmonary Infections

There are approx. 10+ key companies which are developing the therapies for Chronic Pulmonary Infections. The companies which have their Chronic Pulmonary Infections drug candidates in the mid to advanced stage, i.e. phase III and Phase II include, Amrata Pharmaceuticals and others.

Phases

DelveInsight's report covers around 10+ products under different phases of clinical development like

- Late-stage products (Phase III)

- Mid-stage products (Phase II and Phase I/II)

- Early-stage products (Phase I/II and Phase I) along with the details of

- Pre-clinical and Discovery stage candidates

- Discontinued & Inactive candidates

Route of Administration

Chronic Pulmonary Infections pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

- Subcutaneous

- Intravenous

- Oral

- Parenteral

- Intramuscular

- Molecule Type

Products have been categorized under various Molecule types such as

- Small molecules

- Polymer

- Peptides

- Gene Therapy

- Monoclonal antibodies

- Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Chronic Pulmonary Infections: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Chronic Pulmonary Infections therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Chronic Pulmonary Infections drugs.

Chronic Pulmonary Infections Report Insights

- Chronic Pulmonary Infections Pipeline Analysis

- Therapeutic Assessment

- Unmet Needs

- Impact of Drugs

Chronic Pulmonary Infections Report Assessment

- Pipeline Product Profiles

- Therapeutic Assessment

- Pipeline Assessment

- Inactive drugs assessment

- Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:

- How many companies are developing Chronic Pulmonary Infections drugs?

- How many Chronic Pulmonary Infections drugs are developed by each company?

- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Chronic Pulmonary Infections?

- What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Chronic Pulmonary Infections therapeutics?

- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?

- What are the clinical studies going on for Chronic Pulmonary Infections and their status?

- What are the key designations that have been granted to the emerging drugs?

Key Players

- Armata Pharmaceuticals

- Synairgen

- Ionis Pharmaceuticals

- AstraZeneca

- Zambon SpA

- Chiesi Farmaceutici

Key Products

- AP-PA02

- SNG-001

- ION-827359

- MEDI3506

- Colistimethate sodium inhaled

- CHF6001

Chronic Pulmonary Infections - Pipeline Insight, 2021

Table of Contents

Introduction
Executive Summary
Chronic Pulmonary Infections: Overview
• Causes
• Mechanism of Action
• Signs and Symptoms
• Diagnosis
• Disease Management
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
• Assessment by Product Type
• Assessment by Stage and Product Type
• Assessment by Route of Administration
• Assessment by Stage and Route of Administration
• Assessment by Molecule Type
• Assessment by Stage and Molecule Type
Chronic Pulmonary Infections - DelveInsight's Analytical Perspective
In-depth Commercial Assessment
• Chronic Pulmonary Infections companies' collaborations, Licensing, Acquisition -Deal Value Trends
Chronic Pulmonary Infections Collaboration Deals
• Company-Company Collaborations (Licensing / Partnering) Analysis
• Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
• Comparative Analysis
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
• Comparative Analysis
AP-PA02: Armata Pharmaceuticals
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
• Comparative Analysis
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
Chronic Pulmonary Infections Key Companies
Chronic Pulmonary Infections Key Products
Chronic Pulmonary Infections- Unmet Needs
Chronic Pulmonary Infections- Market Drivers and Barriers
Chronic Pulmonary Infections- Future Perspectives and Conclusion
Chronic Pulmonary Infections Analyst Views
Chronic Pulmonary Infections Key Companies
Appendix

List of Tables

Table 1 Total Products for Chronic Pulmonary Infections
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

List of Figures

Figure 1 Total Products for Chronic Pulmonary Infections
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
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