2021 Tumor Markers: Unlocking Mystery of Cancer--US, Europe, Japan--Suppliers Shares and Market Segment Forecasts by Tumor Marker and Country, Competitive Analysis, Technological Breakthroughs, Emerging Markets

2021 Tumor Markers: Unlocking Mystery of Cancer--US, Europe, Japan--Suppliers Shares and Market Segment Forecasts by Tumor Marker and Country, Competitive Analysis, Technological Breakthroughs, Emerging Markets

Table of Contents

I. Introduction
II. Worldwide Market Overview
1. Market Overview
2. Worldwide Market Structure
3. Worldwide Market Size and Growth
III. Major Product Development Opportunities
A. Reagent Kits and Test Systems/Panels
B. Instrumentation
C. Computers, Software and Automation
D. Auxiliary Products
IV. Design Criteria for Decentralized Testing Products
V. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies
1. Marketing Approaches
2. Product Complexity
3. Customer Preference
4. Established Suppliers
5. Emerging Suppliers
6. Major Types of Distributors
7. Market Segmentation Factor
VI. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
Table of Contents

VII. Worldwide Market and Technology Overview
A. Cancer Statistics and Etiology
1. Breast Cancer
2. Lung Cancer
3. Colon and Rectum Cancer
4. Prostate Cancer
5. Stomach Cancer
6. Leukemia
7. Lymphoma
8. Oral Cancer
9. Skin Cancer
10. Uterine Cancer
11. Ovarian Cancer
12. Bladder Cancer
B. Major Current And Emerging Cancer Diagnostic Tests
1. Introduction
2. Tumor Marker Classification
3. ACTH
4. Alpha-Fetoprotein (AFP)
5. Beta-2 Microglobulin
6. CA 15-3/27.29
7. CA 19-9
8. CA-125
9. Calcitonin
10. Carcinoembrionic Antigen (CEA)
11. Estrogen and Progesterone Receptors
12. Ferritin
13. Gastrin
14. Human Chorionic Gonadotropin (HCG)
15. Insulin
16. NSE
17. Occult Blood
18. PAP Smear/HPV
19. Prostatic Acid Phosphatase (PAP)
20. Prostate-Specific Antigen (PSA)
21. Squamous Cell Carcinoma Antigen (SCC)
22. T and B Lymphocytes
Table of Contents

23. TdT
24. Thyroglobulin
25. Tissue Polypeptide Antigen (TPA)
26. Biochemical Tumor Markers
- ADA
- B-Protein
- PNP
- 5'-Nucleotidase
27. Oncogenes
- Abl/abl-bcr
- AIB1
- BCL-2
- BRCA1
- CD44
- C-fos
- C-myb
- C-myc
- CYP-17
- Erb-B
- HPC1
- N-myc
- P40
- P51
- P53
- PIK3CA
- PTI-1
- Ras
- Reg
- Sis
- Src
28. Polypeptide Growth Factors
- Basic Fibroblast Growth Factor
- Beta-TGF
- Cachectin (TNT)
- Calmodulin
- ECFR
- Nerve Growth Factor (NGF)
- Epidermal Growth Factor (EGF)
- Ornithine Decarboxylase
- Transferrin
- Transforming Growth Factor-Alpha
Table of Contents

29. Ectopic Hormones
30. Colony Stimulating Factors
31. Lymphokines
- Alpha-Interferon
- B Cell Growth Factors
- B Cell Growth Factor (BCGF)
- Gamma-Interferon
- Interleukin-1 (IL-1)
- Macrophage Activating Factor
32. Immunohistochemical Stains
33. Emerging Tumor Markers
- N-Acetylglucosamine
- Actin
- Alpha-Actin
- Antineuronal Antibodies
- 7B2
- B72.3
- Bax
- BCD-F9
- BLCA-4
- Blood Group Antigens A,B,H
- CA 50
- CA 72-4/TAG-72
- CA 195
- CA-242
- CA-549
- CAM 26
- CAR-3
- Cathepsin-D
- Chromogranin A and B
- Cluster 1 Antigen
- Cluster-5/5A Antigen
- CTA
- CU18
- DR-70
- DU-PAN-2
- Endometrial Bleeding Associated Factor
- Endostatin
- Epithelial Membrane Antigen
- Feulgen Hydrolysis
- Fibronectin
Table of Contents

- FSH
- (1->3)-L-fucosyltransferase
- Gastrin-Releasing Peptide (GRP)
- GDCFP-15
- Glucagon
- Glycoamines
- H23
- Her-2
- Human Carcinoma Antigen
- HPA
- HSP27
- Intermediate Filaments
- Cytokeratins/CK18/Cyfra 21-1
- Desmin
- Gliofibrillary Acid Protein
- Neurofilaments
- Vimentin
- KA 93
- Kinases
- KP16D3
- LAI
- Leukocyte Common Antigen
- Lewis Antigens
- Lysophosphatidic Acid (LPA)
- Ma 695/Ma 552
- MABDF3
- MAG
- ME1
- Minactivin
- MN/CA9
- MSA
- Mucin Cancer Antigen (MCA)
- Multiple Tumor Suppressor 1
- Myosin
- NEA-130
- NMP22
- OA-519
- Opiod Peptides
- P-glycoprotein
- Pancreatic Oncofetal Antigen (POA)
- Placental Lactogen
- PR92
Table of Contents

- Proliferative Index, Ki-67
- Px
- RB Inactivation/Deletion
- Ret
- SCCL 175
- Selectin
- Sialic Acid
- Sialyl SSEA-1/SLX
- SN10
- Somatostatin
- TA-90
- TABA
- Tachykinin
- TAG 12
- TPS
- Troponin
- Tubulin
- VCAM
- VEGF
- Villen
C. Instrumentation Review And Market Needs
D. Current and Emerging Technologies
1. Molecular Diagnostics
a. Technology Overview b. Amplification Methods c. Sequencing
d. Microarrays/Biochips
2. Monoclonal and Polyclonal Antibodies
3. Immunoassays
a. Technological Principle
b. Radioimmunoassay (RIA)
c. Enzyme Immunoassays (EIA)
- Overview
- ELISA
- Immunofiltration
- Particle-Membrane Capture Immunoassay
- Enzyme Amplification
Table of Contents

d. Fluorescent Immunoassays e. Luminescence
- Chemiluminescence
- Bioluminescence f. Latex Agglutination
g. Immunoprecipitation h. Affinity Chromatographu
e. Liposome Flow-Injection Immunoassay
4. Chromosome Analysis
a. Chronic Myelogenous Leukemia (CML)
b. Acute Myeloid Leukemia (AML)
c. Acute Lymphoblastic Leukemia (ALL)
d. Malignant Lymphomas Lymphoid Malignancies e. Chronic Lymphocytic Leukemia (CLL)
f. Solid Cancers
g. Chromosomal Translocation and Oncogenes
5. Artificial Intelligence
6. Flow Cytometry
7. Two Dimensional Gel Electrophoresis (2-DGE)
8. Biosensors
9. Competing/Complementing Technologies a. CT
b. MRI
c. NMR
d. PET
e. Photonics Spectroscopy
E. Personal Testing
VIII. France
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
Table of Contents

IX. Germany
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
X. Italy
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
XI. Japan
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
XII. Spain
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
XIII. U.K.
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
Table of Contents

XIV. U.S.A.
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers' Sales And Market Shares
XV. Competitive Profiles
- Abbott
- Affymetrix
- Beckman Coulter/Danaher
- Becton Dickinson
- bioMerieux
- Bio-Rad
- Cepheid
- Diamedix
- DiaSorin
- Eiken Chemical
- Elitech Group
- Enzo Biochem
- Fujirebio
- Grifols
- GSK Biologicals
- Hologic
- Leica Biosystems
- Lonza
- Ortho-Clinical Diagnostics
- PerkinElmer
- Qiagen
- Roche
- Scienion
- Sequenom
- SeraCare
- Siemens Healthineers
- Takara Bio
- Thermo Fisher
- Wako
XVI. Appendix: Major Universities and Research Centers Developing Cancer Diagnostic Technology and Applications

List of Tables

Tumor Marker Classification
Major Companies Developing or Marketing ACTH Tests
Major Companies Developing or Marketing AFP Tests
Major Companies Developing or Marketing Beta-2 Microglobulin Tests
Major Companies Developing or Marketing CA 15-3/27.29 Tests
Major Companies Developing or Marketing CA 19-9 Tests
Major Companies Developing or Marketing CA 125 Tests
Major Companies Developing or Marketing Calcitonin Tests
Major Companies Developing or Marketing CEA Tests
Major Companies Developing or Marketing Estrogen Receptor Tests
Major Companies Developing or Marketing Progesterone Receptor Tests
Major Companies Developing or Marketing Ferritin Tests
Major Companies Developing or Marketing Gastrin Tests
Major Companies Developing or Marketing HCG Tests
Major Companies Developing or Marketing Insulin Tests
Major Companies Developing or Marketing NSE Tests
Major Companies Developing or Marketing Occult Blood Tests
Major Companies Developing or Marketing PAP Smear/HPV Tests
Major Companies Developing or Marketing PAP Tests
Major Companies Developing or Marketing PSA Tests
Major Companies Developing or Marketing Lymphocyte Subclassification Tests
Biochemical Markers Potential Applications
In Cancer Diagnosis Oncogenes Potential Applications
In Cancer Diagnosis Major Companies Developing or Marketing Oncogene Tests
Growth Factors Potential Applications
In Cancer Diagnosis Colony Stimulating Factors Potential
Applications In Cancer Diagnosis Lymphokines Potential Applications In Cancer Diagnosis
List of Tables

Immunohistochemical Stains Potential
Applications In Cancer Diagnosis Executive Summary Table: France, Total Cancer
Diagnostic Test Volume and Sales Forecast by Market Segment
France, Laboratories Performing Tumor Marker Tests by Market Segment
France, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
France, Commercial/Private Laboratories Performing Tumor Markers by Annual Test Volume
France, Total Tumor Marker Test Volume Forecast by Market Segment
France, All Market Segments Major Tumor Marker Test Volume Forecast
France, Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
France, Commercial/Private Laboratories Marker Test Volume Forecast
France, Total Tumor Marker Sales Major Tumor Forecast by Market Segment
France, All Market Segments Major Tumor Marker Sales Forecast by Test
France, Hospital Laboratories Major Tumor Marker Sales Forecast by Test
France, Commercial/Private Laboratories Cancer Diagnostics Market Forecast by Test
France, Total Tumor Marker Sales By Major Suppliers
France, AFP Testing Market Diagnostics Sales by Major Supplier
France, CA 15-3 Testing Market Diagnostics Sales by Major Supplier
France, CA 19-9 Testing Market Diagnostics Sales by Major Supplier
France, CA 125 Testing Market Diagnostics Sales by Major Supplier
France, CEA Testing Market Diagnostics Sales by Major Supplier
France, NSE Testing Market Diagnostics Sales by Major Supplier
France, PAP Testing Market Diagnostics Sales by Major Supplier
France, PSA Testing Market Diagnostics Sales by Major Supplier
Executive Summary Table: Germany, Total Tumor Marker Test Volume and Sales Forecast By Market Segment
Germany, Laboratories Performing Tumor Marker Tests by Market Segment
Germany, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
Germany, Commercial/Private Laboratories Performing Tumor Markers by Annual Test Volume
Germany, Total Tumor Marker Test Volume Forecast by Market Segment
Germany, All Market Segments, Major Tumor Marker Test Volume Forecast
Germany, Hospital Laboratories, Major Tumor Marker Test Volume Forecast by Test
Germany, Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
Germany, Physician Offices/Group Practices Major Tumor Marker Test Volume Forecast
Germany, Total Tumor Marker Sales Forecast by Market Segment
Germany, All Market Segments Major Tumor Marker Sales Forecast by Test
Germany, Hospital Laboratories, Major Tumor Marker Sales Forecast by Test
Germany, Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
Germany, Physician Offices/Group Practices Major Tumor Marker Sales Forecast by Test
Germany, Total Tumor Marker Sales By Major Supplier
Germany, AFP Testing Market Diagnostics Sales by Major Supplier
Germany CA 15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
Germany CA 19-9 Testing Market Diagnostics Sales by Major Supplier
Germany, CA 125 Testing Market Diagnostics Sales by Major Supplier
Germany, CEA Testing Market Diagnostics Sales by Major Supplier
Germany, PSA Testing Market Diagnostics Sales by Major Supplier
Executive Summary Table: Italy, Total Tumor Marker Test Volume and Diagnostics Sales Forecast by Market Segment
Italy, Laboratories Performing Tumor Marker Tests by Market Segment
Italy, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
Italy, Commercial/Private Laboratories Performing Tumor Markers by Annual Test Volume
Italy, Total Tumor Marker Test Volume Forecast by Market Segment
Italy, All Market Segments Major Cancer Diagnostic Test Volume Forecast
Italy, Hospital Laboratories Major Tumor Marker Test Volume Forecast
Italy, Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
Italy, Total Tumor Marker Test Market Forecast by Market Segment
Italy, All Market Segments Major Tumor Marker Sales Forecast by Test
Italy, Hospital Laboratories Major Tumor Marker Forecast by Test
Italy, Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
Italy, Total Tumor Markers Sales by Major Suppliers
Italy, AFP Testing Market Diagnostics Sales by Major Supplier
Italy, CEA Testing Market Diagnostics Sales by Major Supplier
Italy, PSA Testing Market Diagnostics Sales by Major Supplier
Executive Summary Table: Japan, Total Tumor Marker Test Volume and Sales Forecast by Market Segment
Japan, Laboratories Performing Tumor Marker Tests by Market Segment
Japan, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
Japan, Commercial/Private Laboratories Performing Tumor Marker Tests By Annual Test Volume
Japan, Total Tumor Marker Testing Volume Forecast by Market Segment
Japan, All Market Segments Major Tumor Marker Test Volume Forecast
Japan, Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
Japan, Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
Japan, Total Tumor Marker Sales Forecast by Market Segment
Japan, All Market Segments Major Tumor Marker Sales Forecast by Test
Japan, Hospital Laboratories Major Tumor Marker Sales Forecast by Test
Japan, Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
Japan, Total Tumor Marker Sales by Major Suppliers
Japan, AFP Testing Market Diagnostics Sales by Major Supplier
Japan, CA 15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
Japan, CA 19-9 Testing Market Diagnostics Sales by Major Supplier
Japan, CA 125 Testing Market Diagnostics Sales by Major Supplier
Japan, Calcitonin Testing Market Diagnostics Sales by Major Supplier
Japan, PAP Testing Market Diagnostics Sales by Major Supplier
Japan, PSA Testing Market Diagnostics Sales by Major Supplier
Executive Summary Table: Spain, Total Tumor Marker Test Volume and Sales Forecast by Market Segment
Spain, Laboratories Performing Tumor Marker Tests by Market Segment
Spain, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
Spain, Commercial/Private Laboratories Performing Tumor Markers by Annual Test Volume
Spain, Total Tumor Marker Test Volume Forecast by Market Segment
Spain, All Market Segment Major Cancer Diagnostic Test Volume Forecast
Spain, Hospital Laboratories Major Cancer Diagnostic Test Volume Forecast by Test
Spain, Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
Spain, Total Tumor Marker Sales Forecast by Market Segment
Spain, All Market Segments Major Tumor Marker Sales Forecast by Test
Spain, Hospital Laboratories Major Tumor Marker Sales Forecast by Test
Spain, Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test Segment
Spain, Total Tumor Marker Sales by Major Suppliers
Spain, AFP Testing Market Diagnostics Sales by Major Supplier
Spain, CA 15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
Spain, 19-9 Testing Market Diagnostics Sales by Major Supplier
Spain, CA 125 Testing Market Diagnostics Sales by Major Supplier
Spain, CEA Testing Market Diagnostics Sales by Major Supplier
Spain, PSA Testing Market Diagnostics Sales by Major Supplier
Executive Summary Table: U.K., Total Tumor Marker Test Volume and Sales Forecast by Market Segment
U.K., Laboratories Performing Tumor Marker Tests by Market Segment
U.K., Hospital Laboratories Performing Tumor Marker Tests by Bed Size
U.K., Commercial/Private Laboratories Performing Tumor Marker Tests by Annual Test Volume
U.K., Total Tumor Marker Testing Volume Forecast by Market Segment
U.K., All Market Segments Major Tumor Marker Test Volume Forecast
U.K., Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
U.K., Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
U.K., Total Tumor Marker Sales Forecast by Market Segment
U.K., All Market Segments Major Tumor Marker Sales Forecast by Test
U.K., Hospital Laboratories Major Tumor Marker Sales Forecast by Test
U.K., Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
U.K., Total Tumor Marker Sales and Market Shares Forecast
U.K., CEA Testing Market Diagnostics Sales by Major Supplier
U.K., PSA Testing Market Diagnostics Sales by Major Supplier
Executive Summary Table: U.S., Total Tumor Marker Test Volume and Sales Forecast By Market Segment
U.S., Laboratories Performing Tumor Marker Tests by Market Segment
U.S., Hospital Laboratories Performing Tumor Marker Tests by Bed Size
U.S., Commercial/Private Laboratories Performing Tumor Marker Tests By Annual Test Volume
U.S., Physician Office Laboratories Performing Tumor Marker Tests By Practice Size
U.S., Total Tumor Marker Test Volume Forecast by Market Segment
U.S., All Market Segments Major Tumor Marker Test Volume Forecast
U.S., Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
U.S., Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
U.S., Physician Offices/Group Practices Major Tumor Marker Test Volume Forecast
U.S., Cancer Clinics Major Tumor Marker Test Volume Forecast by Test
U.S., Total Tumor Marker Sales Forecast by Market Segment
U.S., All Market Segment Major Tumor Marker Sales Forecast by Test
U.S., Hospital Laboratories Major Tumor Marker Sales Forecast by Test
U.S., Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
U.S., Physician Offices/Group Practices Major Tumor Marker Sales Forecast by Test
U.S., Cancer Clinics Major Tumor Marker Sales Forecast by Test
U.S., Total Tumor Marker Sales By Major Supplier
U.S., ACTH Testing Market Diagnostics Sales by Major Supplier
U.S., AFP Testing Market Diagnostics Sales by Major Supplier
U.S., Beta-2 Migroblolulin Testing Market Diagnostics Sales by Major Supplier
U.S., CA 15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
U.S., CA 19-9 Testing Market Diagnostics Sales by Major Supplier
U.S., CA 125 Testing Market Diagnostics Sales by Major Supplier
U.S., CEA Testing Market Diagnostics Sales by Major Supplier
U.S., Ferritin Testing Market Diagnostics Sales by Major Supplier
U.S., HCG Testing Market Diagnostics Sales by Major Supplier
U.S., Insulin Testing Market Diagnostics Sales by Major Supplier
U.S., Parathyroid Hormone Testing Market Diagnostics Sales by Major Supplier
U.S., PSA Testing Market Diagnostics Sales by Major Supplier

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