U.S. Nucleic Acid Testing/NAT Market: Supplier Shares and Strategies, Country Volume and Sales Segment Forecasts, Technology Trends, Instrumentation Review, Opportunities--Infectious Diseases, Genetic Diseases, Cancer, Forensic and Paternity Testing

Publisher Name :
Date: 10-Oct-2016
No. of pages: 1157

Highlights

  • Comprehensive 1,157-page market segmentation analysis of the US NAT market.
  • Major issues pertaining to the US NAT laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next five years.
  • An extensive review of DNA probe and biochip technologies, test formats, detection methodologies, trends in testing automation and amplification methods.
  • Five-year test volume and reagent sales forecasts for the following categories:
                 - Infectious Diseases
                 - Cancer
                 - Forensic Testing
                 - Genetic Diseases
                 - Paternity Testing/HLA Typing
  • Review of testing methodologies and instrumentation technologies.
  • Feature comparison of automated and semiautomated analyzers.
  • Sales and market shares of leading suppliers.
  • Over 60 specific opportunities for NAT instruments, test systems, IT and auxiliary products.
  • Profiles of major suppliers, and emerging market entrants, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
  • Alternative market penetration strategies.
  • Potential market entry barriers and risks.
  • Business planning issues and concerns.

Contains 1,157 pages and 65 tables

U.S. Nucleic Acid Testing/NAT Market: Supplier Shares and Strategies, Country Volume and Sales Segment Forecasts, Technology Trends, Instrumentation Review, Opportunities--Infectious Diseases, Genetic Diseases, Cancer, Forensic and Paternity Testing

Table of Contents

I. Introduction
II. Major Product Development Opportunities
A. Instrumentation
B. Reagent Kits and Test Systems/panels
C. Computers, Software and Automation
D. Auxiliary Products
III. Design Criteria for Decentralized Testing Products
IV. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies For Decentralized Testing Markets
V. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge And Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
VI. Worldwide Market and Technology Review
A. DNA Sequencing
1. Introduction
2. Sequencing Methods
3. Autoradiography
4. The Human Genome Project
5. Sequencing Automation
6. Image Scanners
7. Fluorescent Detection
8. Gene Profiling
9. Gene Expression
10. Polymorphism Screening
11. Protein Interaction Networks
B. DNA and RNA Probe Technologies
1. Basic Principles
2. Probe Preparation
3. The DNA Probe Test
4. Test Formats
5. Labeling Techniques
6. Amplification Methods
C. Detection Technologies
1. Radioactive Methods
a. Overview
b. Major Isotopes
* P-32
* S-35
* H-3
* I-125
2. Non-Isotopic Methods
a. Enzymatic Labels
b. Chemical Labeling
* Indirect Chemical Labeling
* Direct Chemical Labeling
c. Fluorescence
d. Chemiluminescence
e. Electrical Conductivity
D. Molecular Diagnostic Instrumentation Review
1. Abbott LCx
2. Beckman Coulter/Biomek FK
3. BD Viper System with XTR Technology
4. BD Innova
5. Becton Dickinson SDA
6. bioMerieux NucliSENS easyMAG
7. bioMerieux NucliSENS easyQ and MiniMAG
8. Bio-Rad GeneScope
9. Cepheid GeneXpert
10. Curetis Unyvero
11. GenMark Dx eSensor XT-8
12. Hologic/Gen-Probe Panther
13. Hologic/Gen-Probe Tigris/DTS
14. HTG Molecular Edge
15. Life Technologies QuantStudio Dx
16. Qiagen QIAsymphony RGQ
17. Roche Cobas Amplicor
18. Roche Cobas TaqMan 48
19. Roche Cobas TaqMan
20. Roche Cobas TaqMan AmpliPrep
21. Roche LighCycler 480
22. Roche Cobas 4800
23. Roche Cobas s 201
24. Siemens Versant
25. Tecan LS Series
E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
- Liquid Transportation and Mixing
- Separation
- Reaction
- Detection
F. Pharmacogenomics
G. Major Applications
1. Microbiology/Infectious Diseases
a. Overview
b. Major Infectious Diseases
- AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT, Western Blot, HTLV-I/II
- Adenovirus
- Aeromonas
- Anthrax/Bacillus Anthracis
- Arboviruses
- Babesiosis
- Bacillary Epithelioid Angiomatosis (BEA) and Other Bartonella (Rochalimaea)
- Blastocystis Hominis
- Brucella
- Campylobacter
- Candida
- Chagas Disease
- Chancroid
- Chlamydia
- Clostridium Difficile
- Coronaviruses
- Coxsackieviruses
- Creutzfeldt-Jakob's Disease
- Cryptosporidium Parvum
- Cyclospora Cayetanensis
- Cytomegalovirus
- Ebola Virus
- E. Coli
- EchoVirus
- Encephalitis
- Enteroviruses
- Epstein-Barr Virus
- Giardia Lamblia
- Gonorrhea
- Granuloma Inguinale
- Hantavirus
- Helicobacter Pylori
- Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT, Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag, HBe Ag, ALT/SGPT
- Herpes Simplex Virus
- Human Herpes Virus-6 (HHV-6)
- Influenza Viruses
- Legionella
- Lyme Disease
- Lymphogranuloma Venereum (LGV)
- Malaria
- Measles (Rubeola)
- Meningitis
- Microsporidium
- Mononucleosis
- Mumps
- Mycoplasma
- Papillomaviruses
- Parvovirus B19
- Pneumonia
- Polyomaviruses
- Pseudomonas Aeruginosa
- Rabies
- Respiratory Syncytial Virus (RSV)
- Rhinoviruses
- Rotavirus
- Rubella
- Salmonellosis
- Septicemia
- Shigellosis
- Staphylococcus Aureus
- Streptococci
- Syphilis
- Toxoplasmosis
- Trichomonas Vaginalis
- Tuberculosis
- Vibrio
- West Nile Virus
- Yersina
2. Cancer Testing
a. Overview
b. Major Cancer Types
* Prostate
* Lung
* Colon and Rectum
* Breast
* Skin
* Uterine
* Leukemia
* Oral
c. Oncogenes
* Abl/abl-bcr
* AIB1
* BCL-2
* BRCA1
* CD44
* C-fos
* C-myb
* C-myc
* CYP17
* Erb-B
* HPC1
* N-myc
* P40
* P51
* P53
* PIK3CA
* PTI-1
* Ras
* Reg
* Sis
* Src
3. Genetic Diseases
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
* Achondroplasia
* Autosomal Dominant Polycystic Kidney Disease
* Cancer
* Cosmetogenomics
* Cystic Fibrosis
* Down's Syndrome
* Duchenne and Becker Muscular Dystrophy
* Factor V (Leiden)
* Factor IX Deficiency
* Fragile X Syndrome
* Heart Disease
* Hemochomatosis
* Hemophilia
* Huntington's Disease
* Maternal-Fetal Incompatibility
* Multiple Endocrine Neoplasia
* Phenylketonuria (PKU)
* Polycystic Kidney Disease (PKD)
* Prenatal Screening
* Retinitis Pigmentosa
* Retinoblastoma
* Sickle Cell Anemia
* Spinal Muscular Atrophy
* Vitamin B12 Metabolism
i. Social Issues and Concerns
4. Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
* Multilocus Probes
* Single Locus Probes
* PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
* U.S.A.
* U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe
Market Expansion
* Technology Availability
* Use of Hair as Evidence
h. Wildlife Forensics
5. Paternity Testing/HLA Typing
6. Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
H. Competing/complementing
1. Monoclonal Antibodies/Immunoassays
2. RNA Probes
3. Two-Dimensional Electrophoresis
4. Flow Cytometry
VII. U.S.A. Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts, Major Supplier Sales and Market Shares
VIII. Competitive Assessments
- Abbott
- Affymetrix
- Agilent Technologies
- Applied Gene Technologies
- Arca Biopharma
- Beckman Coulter/Danaher
- Becton Dickinson
- Biokit
- bioMerieux
- Bio-Rad
- Biotest
- Cepheid
- CellMark Forensics/LabCorp
- Decode Genetics
- Diadexus
- Eiken
- Elitech Group
- Enzo
- Exact Sciences
- Fujirebio
- Grifols
- Hologic/Gen-Probe
- Illumina
- Kreatech/Leica
- Li-Cor Biosciences
- Monogram Biosciences/LabCorp
- Myriad Genetics
- Ortho-Clinical Diagnostics
- Perkin Elmer/Caliper
- Proteome Sciences
- Qiagen
- Roche
- Scienion
- Sequenom
- Shimadzu
- Siemens
- Sierra Molecular
- Takara Bio
- Tecan Group
- Thermo Fisher
XIII. Appendix: Major Universities and Research Centers Developing Molecular Diagnostic Technologies

List of Tables

Major Companies Developing or Marketing AIDS Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Bartonella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Candida Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Clostridium Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Coronavirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Cryptosporidium Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Echovirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Enterovirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Giardia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Hantavirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Helicobacter Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Herpes Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Influenza Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Legionella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Measles Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Meningitis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Mononucleosis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Mumps Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing RSV Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Rotavirus Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Rubella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Septicemia Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Shigella Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Syphilis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Trichomonas Molecular Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic and Other Direct Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular Diagnostic Tests For Genetic Diseases
U.S.A. Molecular Diagnostics Test Volume And Sales by Major Application
U.S.A. Laboratories Performing DNA Sequencing by Market Segment
U.S.A. Molecular Diagnostics Market Potential Laboratory Universe by Market Segment 2014
U.S.A. Molecular Diagnostics Test Volume by Major Application
U.S.A. Major Infectious Disease Test Volume by Assay
U.S.A. Major Infectious Disease Test Volume by Method
U.S.A. Molecular Diagnostics Market by Major Application
U.S.A. Molecular Diagnostics Market Estimated Sales and Market Shares of Major Suppliers
U.S.A. Major Infectious Disease Diagnostics Market by Assay
U.S.A. AIDS Testing Market Estimated Sales by Major Supplier
U.S.A. Adenovirus Testing Market Estimated Sales by Major Supplier
U.S.A. Chlamydia Testing Market Estimated Sales by Major Supplier
U.S.A. CMV Testing Market Estimated Sales by Major Supplier
U.S.A. Echovirus Testing Market Estimated Sales by Major Supplier
U.S.A. Enterovirus Testing Market Estimated Sales by Major Supplier
U.S.A. EBV Testing Market Estimated Sales by Major Supplier
U.S.A. Gonorrhea Testing Market Estimated Sales by Major Supplier
U.S.A. Hepatitis Testing Market Estimated Sales by Major Supplier
U.S.A. Hepatitis C Testing Market Estimated Sales by Major Supplier
U.S.A. HIV/Hepatitis Blood Screening NAT Market Reagent Sales by Major Supplier
U.S.A. Herpes Testing Market Estimated Sales by Major Supplier
U.S.A. Influenza Testing Market Estimated Sales by Major Supplier
U.S.A. Meningitis Testing Market Estimated Sales by Major Supplier
U.S.A. Mycoplasma Testing Market Estimated Sales by Major Supplier
U.S.A. Pneumonia Testing Market Estimated Sales by Major Supplier
U.S.A. Rabies Testing Market Estimated Sales by Major Supplier
U.S.A. RSV Testing Market Estimated Sales by Major Supplier
U.S.A. Salmonella Testing Market Estimated Sales by Major Supplier
U.S.A. Shigella Testing Market Estimated Sales by Major Supplier
U.S.A. West Nile Virus Nat Market Reagent Sales by Major Supplier
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