US Market Report for Contrast Agents and Injectors 2016 - MedCore

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Date: 01-Sep-2016
No. of pages: 104
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Description

This market value does not include the contrast injector segment, as it is a capital-based market instead of consumable-based. In 2015, the MRI contrast agent segment comprised the largest portion of this market. Despite having a lower sales volume, the higher ASP of MRI contrast agents compared to X-Ray CT contrast agents, has allowed this segment to increase in market share. Conversely, stagnant unit growth and decreasing ASPs has caused the X-Ray CT contrast agent segment to experience a decline in market share. Ultrasound contrast agents command the highest ASP and will exhibit a gradually increasing market share driven by sales growth.

Abstract

The U.S. market for contrast agents and injectors includes X-ray and CT agents, MRI agents and ultrasound agents as well as contrast injectors. In 2015, MRI contrast agents represented the largest segment in the contrast agent and injector market. This segment will continue to have the highest market value driven by increasing procedural volumes.

Companies


  • GE Healthcare

  • Siemens Healthcare

  • Philips Healthcare

  • Bayer

  • Hologic

  • Toshiba Medical Systems


Others include: Accutome, Agfa Healthcare, Amrad Medical, Analogic, Arcoma-IMIX, Assured Imaging Mobile Mammography, BK Medical, Bracco, C.R. Bard, Canon, Carestream Health, CMR-Naviscan, Cuattro, Del Medical, Digirad, Dilon Technologies, Ellex/Innovative Imaging, Esaote, eZono, Fischer-Giotto, FONAR, Fujifilm, Gamma Medica Inc., Guerbet, Hitachi Medical Systems, iCRco, Imaging Dynamics Company, IMRIS, Konica Minolta, Lakeshore Technologies Inc., Lantheus Medical Imaging, Machnet B.V., Mallinckrodt, MILabs, Mindray, Neusoft Medical Systems, Paradigm, Planmed OY, Quantel Medical, Rayence, Samsung Medison, Shimadzu, SonoCiné, Sonogage, Sonomed Escalon, SonoSite, Spectrum Dynamics Medical, SuperSonic Imagine, SuperSonic Imagine, Swissray, Teleflex, Terason, Tomey, TXR, ViewRay, Zonare, etc.

US Market Report for Contrast Agents and Injectors 2016 - MedCore

Table of Contents

Table Of Contents I
List Of Figures Xx
List Of Charts Xxv

Executive Summary 1
U.S. Medical Imaging Device Market Overview 1
Competitive Analysis 3
Market Trends 6
Market Developments 8
Procedure Codes Investigated 9
Procedures Included 12
Markets Included 16
Key Report Updates 19
Version History 19

Research Methodology 20
1.1 Research Scope 20
1.2 Idata's 9-Step Methodology 20
Step 1: Project Initiation & Team Selection 20
Step 2: Prepare Data Systems and Perform Secondary Research 22
Step 3: Preparation for Interviews & Questionnaire Design 23
Step 4: Performing Primary Research 24
Step 5: Research Analysis: Establishing Baseline Estimates 26
Step 6: Market Forecast and Analysis 27
Step 7: Identify Strategic Opportunities 29
Step 8: Final Review and Market Release 30
Step 9: Customer Feedback and Market Monitoring 31

Product Assessment 32
2.1 Product Portfolios 32
2.1.1 Contrast Agents and Power Injectors 32
2.1.1.1 Applications 32
2.1.1.1.1 X-Ray and CT 32
2.1.1.1.2 MRI 34
2.1.1.1.3 Ultrasound 35
2.2 Regulatory Issues And Recalls 37
2.2.1 Power Injectors 37
2.3 Clinical Trials 38
2.3.1 Bayer 39
2.3.2 Bracco 39
2.3.3 Carestream Health 42
2.3.4 Fujifilm 45
2.3.5 GE Healthcare 48
2.3.6 Guerbet 65
2.3.7 Hologic 69
2.3.8 Lantheus Medical Imaging 70
2.3.9 Philips Healthcare 70
2.3.10 Siemens Healthcare 77
2.3.11 Toshiba Medical Systems 79

Contrast Agent And Injector Market 81
3.1 Market Overview 81
3.2 Market Analysis And Forecast 84
3.2.1 Total Contrast Agent Market 84
3.2.1.1 X-Ray/CT Contrast Agent Market 86
3.2.1.2 MRI Contrast Agent Market 88
3.2.1.3 Ultrasound Contrast Agent Market 90
3.2.2 Contrast Injector Market 92
3.3 Drivers And Limiters 94
3.3.1 Market Drivers 94
3.3.2 Market Limiters 95
3.4 Competitive Market Share Analysis 96

Abbreviations 102

Appendix: Company Press Releases 104

List of Charts

Chart 1 1: Medical Imaging Device Market by Segment, U.S., 2012 - 2022 2
Chart 1 2: Medical Imaging Device Market Overview, U.S., 2012 & 2022 2
Chart 3 1: Contrast Agent and Injector Market by Segment, U.S., 2012 - 2022 82
Chart 3 2: Contrast Agent and Injector Market Breakdown, U.S., 2015 83
Chart 3 3: Contrast Agent and Injector Market Breakdown, U.S., 2022 83
Chart 3 4: Total Open MRI Market by Segment, U.S., 2012 - 2022 85
Chart 3 5: X-Ray/CT Contrast Agent Market, U.S., 2012 - 2022 87
Chart 3 6: MRI Contrast Agent Market, U.S., 2012 - 2022 89
Chart 3 7: Ultrasound Contrast Agent Market, U.S., 2012 - 2022 91
Chart 3 8: Contrast Injector Market, U.S., 2012 - 2022 93
Chart 3 9: Leading Competitors, Contrast Agent and Injector Market, U.S., 2015 99
Chart 3 10: Leading Competitors, Contrast Agent Market, U.S., 2015 100
Chart 3 11: Leading Competitors, Contrast Injector Market, U.S., 2015 101

List of Figures

Figure 1 1: Medical Imaging Device Competitor Market Share Ranking by Segment, U.S., 2015 (1 of 2) 3
Figure 1 2: Medical Imaging Device Competitor Market Share Ranking by Segment, U.S., 2015 (2 of 2) 3
Figure 1 3: Companies Researched in this Report, U.S., 2015 (1 of 2) 4
Figure 1 4: Companies Researched in this Report, U.S., 2015 (2 of 2) 5
Figure 1 5: Factors Impacting the Medical Imaging Device Market by Segment, U.S. (1 of 2) 6
Figure 1 6: Factors Impacting the Medical Imaging Device Market by Segment, U.S. (2 of 2) 7
Figure 1 7: Recent Events in the Medical Imaging Device Market, U.S., 2012 - 2015 8
Figure 1 8: Procedure Codes Investigated, U.S., 2015 (1 of 3) 9
Figure 1 9: Procedure Codes Investigated, U.S., 2015 (2 of 3) 10
Figure 1 10: Procedure Codes Investigated, U.S., 2015 (3 of 3) 11
Figure 1 11: Medical Imaging Procedures Covered, U.S., 2015 (1 of 4) 12
Figure 1 12: Medical Imaging Device Markets Covered, U.S., 2015 (1 of 3) 16
Figure 1 13: Medical Imaging Device Markets Covered, U.S., 2015 (2 of 3) 17
Figure 1 14: Medical Imaging Device Markets Covered, U.S., 2015 (3 of 3) 18
Figure 1 15: Key Report Updates 19
Figure 1 16: Version History 19
Figure 2 1: X-Ray and CT Contrast Agents by Company 33
Figure 2 2: X-Ray and CT Power Injectors by Company 34
Figure 2 3: MRI Contrast Agents by Company (1 of 2) 34
Figure 2 4: MRI Contrast Agents by Company (2 of 2) 35
Figure 2 5: MRI Power Injectors by Company 35
Figure 2 6: Ultrasound Contrast Agents by Company 36
Figure 2 7: Class 2 Device Recall Medrad Mark 7 Arterion Injection System 37
Figure 2 8: Class 2 Device Recall GEHC OEC Injection Cable for MedRad Provis V Contrast Injector 37
Figure 2 9: Perfusion CT as a Predictor for Response to Antiangiogenic Therapy 39
Figure 2 10: A Multicenter Study of Iomeron®-400 39
Figure 2 11: Retrospective Study of MRI in Pediatric Patients 40
Figure 2 12: A Pilot Trial Using BR55 Ultrasound Contrast Agent 40
Figure 2 13: Crossover Comparison of MultiHance and Dotarem (BENEFIT) 40
Figure 2 14: Multidetector Computed Tomography (MDCT) Tailored Protocol 41
Figure 2 15: Reproducibility and Repeatability of Multifunctional MRI Biomarkers of the Body 41
Figure 2 16: Reproducibility and Repeatability of Multifunctional MRI Biomarkers of the Body 42
Figure 2 17: CARESTREAM Vue PACS v12.1.5 CT Perfusion Clinical Protocol (CTP) 42
Figure 2 18: Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis 43
Figure 2 19: Clinical Evaluation of the Carestream PRO 3543 and PRO 3543C Digital Detectors 43
Figure 2 20: Clinical Evaluation of DRX Plus 3543 and DRX Plus 3543C Digital Detectors 44
Figure 2 21: Carestream Digital Radiography Long Length Imaging Software Data Collection Protocol (LLI-MSE) 44
Figure 2 22: A Multi-Reader Multi-Case Pivotal Trial 45
Figure 2 23: Pilot Mammography Reader Study 45
Figure 2 24: Acquisition of Breast Mammography Images 46
Figure 2 25: Study Comparing Flexible Spectral-Imaging Color Enhancement (FICE) With Olympus Narrow Band Imaging (NBI) 46
Figure 2 26: Pilot 3D Mammography Reader Study to Assess Breast Cancer Detection 46
Figure 2 27: Pilot Study Comparing Diagnostic Imaging Versus Tomosynthesis in Detection of Hip, Wrist or Tibia Injury (TOMO) 47
Figure 2 28: Collection of FUJIFILM's 3Dimensional Mammograms (3DM) 47
Figure 2 29: International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients 48
Figure 2 30: Advanced MRI Applications for Mild Traumatic Brain Injury-Phase 2 (mTBI-phase2) 48
Figure 2 31: Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis 49
Figure 2 32: Non-invasive Quantification of Liver Iron With MRI 49
Figure 2 33: Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis 50
Figure 2 34: Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis 50
Figure 2 35: Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit (Firefly) 51
Figure 2 36: Phase 4 Study to Demonstrate Prognostic Usefulness of AdreView™ Scintigraphy 51
Figure 2 37: Clinical Evaluation of an Integrated PET/MRI System (PET/MR_ZURICH) 52
Figure 2 38: Automated Breast Ultrasound and Digital Breast Tomosynthesis Screening 52
Figure 2 39: Development of an Integrated PET/MR System, Accessories and Components 53
Figure 2 40: Comparison of 18F FDG PET/CT TO PET MRI (PET/MR US) 53
Figure 2 41: Compare Rates of Agreement Between Clinical Diagnosis and Visual Assessment of DaTscan™ Images 54
Figure 2 42: Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView 54
Figure 2 43: Clinical Evaluation for GE CT System 55
Figure 2 44: A Case Collection Study for Digital Breast Tomosynthesis (DBT) 55
Figure 2 45: Assess Safety, Bio-distribution, Radiation Dosimetry and Optimize the Imaging Protocol of GEH120714 (18F) Injection 56
Figure 2 46: Magnetic Resonance Imaging Using Innovative Pulse Sequences 56
Figure 2 47: MRI Scanning of People With MR Safe Orthopedic Implants That Are Made of Metal (MRI) 56
Figure 2 48: Contrast Ultrasound Detection of Sentinel Lymph Nodes 57
Figure 2 49: Feasibility of Short Breast MRI (SBMRI) for Screening Patients at High Risk for Breast Cancer 57
Figure 2 50: PET/CT for Staging Rectal Cancer Patients With and Without EMVI-MR 58
Figure 2 51: Contrast Enhanced Spectral Mammography (CESM) Study (CONTEND) 58
Figure 2 52: Assessment of Automated Breast Ultrasound 59
Figure 2 53: Feasibility of Ultrasound Microbubble Contrast-Enhanced (CEUS) Sentinel Lymph Node Imaging 59
Figure 2 54: How Beta-amyloid Imagining Influences Clinician Diagnosis and Management 60
Figure 2 55: Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas 60
Figure 2 56: Use of MIBG Scan Images in PVC Ablations (PVC-MIBG) 60
Figure 2 57: Comparison of Contrast-enhanced Spectral Mammography (CESM) to MRI 61
Figure 2 58: Fluoro-L-Thymidine Positron Emission Tomography (FLT PET) vs. Adv. Magnetic Resonance (MR) Techniques 61
Figure 2 59: A Pilot, Exploratory, Non-Randomized Study of PET/CT With the Investigational Agent [18F] Fluciclatide 62
Figure 2 60: 123I-mIBG SPECT Imaging 62
Figure 2 61: Preoperative Staging and Dose Escalated Radiotherapy of Prostate Carcinoma With PET and MRI (Flucipro) 63
Figure 2 62: FACBC PET and PEM as a Staging Tool and Indicator of Therapeutic Response in Breast Cancer Patients 63
Figure 2 63: The Assessment of Molecular Breast Imaging (MBI) in Distinguishing Benign From Malignant Breast Disease 64
Figure 2 64: Imaging Biomarkers of Delayed Sequelae in Trauma Brain Injury 64
Figure 2 65: Safety and Efficacy of Lipiodol® Ultra Fluid in Association With Surgical Glues During Vascular Embolization (In-Live) 65
Figure 2 66: P03277 Dose Finding Study in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) 65
Figure 2 67: Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI 66
Figure 2 68: Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI 66
Figure 2 69: Evaluation of Gadoterate in Patients With Decreased Kidney Function 67
Figure 2 70: Lipiodol as an Imaging Biomarker in Patients With Primary and Metastatic Liver Cancer 67
Figure 2 71: Hepatic Xenetix-CT Perfusion 68
Figure 2 72: Effects Contrast on Platelet Activity, Thrombosis and Fibrinolysis 68
Figure 2 73: Pancreatic Duct Evaluation in Autoimmune Pancreatitis: MR Pancreatography 69
Figure 2 74: Computed Tomography Versus Standard 2D Mammography Versus 3D Tomosynthesis 69
Figure 2 75: Open Label Study to Access Flurpiridaz F18 in PET MPI Verses SPECT MPI 70
Figure 2 76: Virtual Path Planning for Image-guided Needle Interventions 70
Figure 2 77: Applications of Dual-Energy Computed Tomography 71
Figure 2 78: X-ray Dose Reduction Study for Cardiac Angiography and Intervention 71
Figure 2 79: X-ray Dose Reduction Study for Endovascular Interventional Radiology 71
Figure 2 80: X-ray Dose Reduction in Electrophysiology 72
Figure 2 81: Multicenter Study of Magnetic Resonance-guided High Intensity Focused Ultrasound 72
Figure 2 82: MRI/TRUS Fusion Guided Prostate Biopsy- An Improved Way to Detect and Quantify Prostate Cancer 72
Figure 2 83: Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids (SOFIA) 73
Figure 2 84: Cardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter 73
Figure 2 85: Percutaneous Closure of Atrial Septal Defects in Children 74
Figure 2 86: Assessment of 3D Transperineal Ultrasound Imaging w/ Matrix Array Transducers in Prostate Radiotherapy 74
Figure 2 87: Radio Frequency Ablation for Atrial Flutter With Magnetic Resonance Guidance and Tracking 75
Figure 2 88: Chest Ultrasound of ER Patients With Cough or SOB 75
Figure 2 89: The Value of MultiSpectral 3 Tesla MRI in Active Surveillance of Prostate Cancer 76
Figure 2 90: Multi Modal Cardiac Imaging Prior Transcatheter Aortic Valve Implantation 76
Figure 2 91: MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastases 77
Figure 2 92: Evaluation of Diagnostic Accuracy of Contrast Enhanced Dual Energy Mammography Imaging 77
Figure 2 93: Evaluation of an Innovative Medical Device Supporting Orthopedic Surgical Interventions (VIPS) 78
Figure 2 94: PET/MRI in Patients With Suspected Prostate Cancer 78
Figure 2 95: Perfusion CT as a Predictor for Response to Antiangiogenic Therapy 79
Figure 2 96: Verification of the Quantitative Accuracy of the PET/CT System Imaging Chain 79
Figure 2 97: General Investigative MRI Protocol 80
Figure 3 1: Contrast Agent and Injector Market by Segment, U.S., 2012 - 2022 (US$M) 82
Figure 3 2: Total Open MRI Market by Segment, U.S., 2012 - 2022 (US$M) 84
Figure 3 3: X-Ray/CT Contrast Agent Market, U.S., 2012 - 2022 86
Figure 3 4: MRI Contrast Agent Market, U.S., 2012 - 2022 88
Figure 3 5: Ultrasound Contrast Agent Market, U.S., 2012 - 2022 90
Figure 3 6: Contrast Injector Market, U.S., 2012 - 2022 92
Figure 3 7: Drivers and Limiters, Contrast Agent and Injector Market, U.S., 2015 95
Figure 3 8: Leading Competitors, Contrast Agent and Injector Market, U.S., 2015 98
Figure 3 9: Leading Competitors, Contrast Agent Market, U.S., 2015 100
Figure 3 10: Leading Competitors, Contrast Injector Market, U.S., 2015 101
Figure 5 1: Press Release Summary 105

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