Single-use Bioreactor Market by Product (Stem cells, Interferons), Cell (Yeast, Plant cells), Technology (Bubble column bioreactors), Application (R&D, Bioproduction), End User (R&D department, Biopharmaceutical manufacturers) - Global Forecast to 2021

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Date: 04-Oct-2016
No. of pages: 148
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The global single-use bioreactors market is projected to reach USD 1,085.7 million by 2021 from USD 408.4 million in 2016, growing at a CAGR of 21.6% during the forecast period (2016–2021). In this report, the single-use bioreactors market is broadly segmented on the basis of product type, cell type, technology, application, end user, and region. Factors such as improved return on investment for small companies and startups, reduced complexity in automation, and positive impact on the environment are driving the growth of the single-use bioreactors market.

On the basis of cell type, the single-use bioreactors market is categorized into mammalian cells, bacteria, yeast, and other cells (insect and plant cells). In 2016, the monoclonal antibodies segment is expected to account for the largest share of the single-use bioreactors market. Factors such as reduced risk of contamination and easy implementation in bioproduction are driving the adoption of SUBs for the production of these molecules. Based on technology, the single-use bioreactors market is categorized into wave-induced motion SUBs, stirred SUBs, single-use bubble column bioreactors, and others technologies. The wave-induced motion SUBs segment is expected to account for the largest market share in 2016. Growth in this segment can be attributed to the advantages offered by this technology such as high flexibility and shorter lead times.

Europe is expected to account for the largest share of the single-use bioreactors market in 2016. Patent cliff of many biologics drugs in Europe and government support for pharmaceutical companies to launch new biologics therapies with superior efficacy are driving the growth of the single-use bioreactors market in this region. The APAC single-use bioreactors market is expected to register the highest CAGR of 23.4% in the next five years. The rapidly growing healthcare industry and increasing investments by major pharmaceutical companies in this region are contributing to the high growth of the APAC single-use bioreactors market during the forecast period.

Product launches was the most widely adopted growth strategy pursued by players in the single-use bioreactors market, to increase their shares and cater to the unmet needs. The major players operating in the single-use bioreactors market include Sartorius Stedim Biotech S.A. (France), Merck Millipore (Germany), GE Healthcare (U.S.), Danaher Corporation (U.S.), and Thermo Fisher Scientific Inc. (U.S.).

Reasons to buy this report:

This report will enable both established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in turn will help these firms, garner greater market shares. Firms purchasing the report can use any one or a combination of the below-mentioned five strategies (market penetration, product development/innovation, market development, market diversification, and competitive assessment) for strengthening their market shares.

The report provides insights on the following pointers:


  • Market Penetration: Comprehensive information on the product portfolios of the top players in the single-use bioreactors market. The report provides an analysis of the single-use bioreactors market, by product type, cell type, application, technology, end user, and region

  • Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and new product launches in the single-use bioreactors market

  • Market Development: Comprehensive information about lucrative emerging markets. This report provides an analysis of the single-use bioreactors market across regions

  • Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments in the global single-use bioreactors market

  • Competitive Assessment: In-depth assessment of market strategies, product portfolios, and manufacturing capabilities of the leading players in the global single-use bioreactors market

Single-use Bioreactor Market by Product (Stem cells, Interferons), Cell (Yeast, Plant cells), Technology (Bubble column bioreactors), Application (R&D, Bioproduction), End User (R&D department, Biopharmaceutical manufacturers) - Global Forecast to 2021

Table of Contents

1 Introduction
1.1 Objectives of the Study
1.2 Market Definition
1.2.1 Markets Covered
1.2.2 Years Considered for the Study
1.3 Currency
1.4 Limitations
1.5 Stakeholders

2 Research Methodology
2.1 Market Size Estimation
2.2 Market Breakdown and Data Triangulation
2.2.1 Key Data From Secondary Sources
2.2.2 Key Data From Primary Sources
2.2.2.1 Key Industry Insights
2.3 Assumptions for the Study

3 Executive Summary
3.1 Introduction
3.2 Conclusion

4 Premium Insights
4.1 Single-Use Bioreactors: Market Overview
4.2 Geographical Analysis: Market, By Cell Type (2016)
4.3 Market, By End User
4.4 Market, By Technology
4.5 Geographical Snapshot of the Market

5 Market Overview
5.1 Introduction
5.2 Market Dynamics
5.2.1 Drivers
5.2.1.1 Increasing Adoption of Subs Among Small Companies and Startups
5.2.1.2 Reduced Automation Complexity
5.2.1.3 Ease in Cultivation of Marine Organisms (Algae)
5.2.1.4 Reduced Environmental Impact
5.2.2 Restraints
5.2.2.1 Regulatory Concerns Related to Subs
5.2.2.2 Issues Regarding Leachables and Extractables
5.2.3 Opportunities
5.2.3.1 Growing Biologics Market
5.2.3.2 Patent Expiry
5.2.4 Challenges
5.2.4.1 Limitations in Flexible Bioreactors
5.2.4.2 Need for Improved Single-Use Sensors

6 Industry Insights
6.1 Industry Insights
6.2 Supply Chain Analysis
6.3 Pestel Analysis
6.3.1 Political Factors
6.3.2 Economic Factors
6.3.3 Social Factors
6.3.4 Technological Factors
6.3.5 Environmental Factors
6.3.6 Legal Factors

7 Single-Use Bioreactors Market, By Product Type
7.1 Introduction
7.2 Monoclonal Antibodies (MABS)
7.3 Vaccines
7.4 Recombinant Proteins
7.5 Stem Cells
7.6 Gene-Modified Cells
7.7 Other Products

8 Single-Use Bioreactors Market, By Type of Cell
8.1 Introduction
8.2 Mammalian Cells
8.3 Bacterial Cells
8.4 Yeast Cells
8.5 Other Cells

9 Single-Use Bioreactors Market, By Technology
9.1 Introduction
9.2 Wave-Induced Motion Single-Use Bioreactors
9.3 Stirred Single-Use Bioreactors
9.4 Single-Use Bubble Column Bioreactors
9.5 Other Technologies

10 Single-Use Bioreactors Market, By Application
10.1 Introduction
10.2 Bioproduction
10.3 Process Development
10.4 Research & Development

11 Global Single-Use Bioreactors Market, By End User
11.1 Introduction
11.2 Biopharmaceutical Manufacturers
11.3 R&D Departments

12 Global Single-Use Bioreactors Market, By Region
12.1 Introduction
12.2 North America
12.2.1 U.S.
12.2.2 Canada
12.3 Europe
12.3.1 U.K.
12.3.2 Germany
12.3.3 Rest of Europe (RoE)
12.4 Asia-Pacific
12.5 Rest of the World (RoW)

13 Competitive Landscape
13.1 Overview
13.2 Competitive Situation and Trends
13.2.1 Product Launches
13.2.2 Acquisitions
13.2.3 Collaborations
13.2.4 Others

14 Company Profiles
14.1 Introduction
(Business Overview, Products & Services, Key Insights, Recent Developments, SWOT Analysis, Ratio Analysis, MnM View)*
14.2 Sartorius Stedim Biotech S.A.
14.3 Merck Millipore
14.4 GE Healthcare
14.5 Danaher Corporation
14.6 Thermo Fisher Scientific, Inc.
14.7 Parker Hannifin Corporation
14.8 Applikon Biotechnology
14.9 Cellexus Limited
14.10 Celltainer Biotech BV
14.11 PBS Biotech, Inc.

*Details on Business Overview, Products & Services, Key Insights, Recent Developments, SWOT Analysis, MnM View Might Not Be Captured in Case of Unlisted Companies.

15 Appendix
15.1 Insights of Industry Experts
15.2 Discussion Guide
15.3 Other Developments
15.4 Knowledge Store: Marketsandmarkets’ Subscription Portal
15.5 Introducing RT: Real-Time Market Intelligence
15.6 Available Customizations
15.7 Related Reports

List of Tables

Table 1 Typical Extractables for Acceptable Materials Used in Disposable Bioprocess Manufacturing Systems
Table 2 Single-Use Bioreactors Market Size, By Product Type, 2014-2021 (USD Million)
Table 3 Market Size for MABS, By Region, 2014-2021 (USD Million)
Table 4 North America: Market Size for MABS, By Country, 2014–2021 (USD Million)
Table 5 Europe: Market Size for MABS, By Country, 2014–2021 (USD Million)
Table 6 Market Size for Vaccines, By Region, 2014-2021 (USD Million)
Table 7 North America: Market Size for Vaccines, By Country, 2014–2021 (USD Million)
Table 8 Europe: Market Size for Vaccines, By Country, 2014–2021 (USD Million)
Table 9 Market Size for Recombinant Proteins, By Region, 2014-2021 (USD Million)
Table 10 North America: Market Size for Recombinant Proteins, By Country, 2014–2021 (USD Million)
Table 11 Europe: Market Size for Recombinant Proteins, By Country, 2014–2021 (USD Million)
Table 12 Market Size for Stem Cells, By Region, 2014-2021 (USD Million)
Table 13 North America: Market Size for Stem Cells, By Country, 2014–2021 (USD Million)
Table 14 Europe: Market Size for Stem Cells, By Country, 2014–2021 (USD Million)
Table 15 Market Size for Gene-Modified Cells, By Region, 2014-2021 (USD Million)
Table 16 North America: Market Size for Gene-Modified Cells, By Country, 2014–2021 (USD Million)
Table 17 Europe: Market Size for Gene-Modified Cells, By Country, 2014–2021 (USD Million)
Table 18 Market Size for Other Products, By Region, 2014-2021 (USD Million)
Table 19 North America: Market Size for Other Products, By Country, 2014–2021 (USD Million)
Table 20 Europe: Market Size for Other Products, By Country, 2014–2021 (USD Million)
Table 21 Global Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 22 Global Market Size for Mammalian Cells, By Region, 2014–2021 (USD Million)
Table 23 Europe: Market Size for Mammalian Cells, By Country, 2014–2021 (USD Million)
Table 24 North America: Market Size for Mammalian Cells, By Country, 2014–2021 (USD Million)
Table 25 Global Market Size for Bacterial Cells, By Region, 2014–2021 (USD Million)
Table 26 Europe: Market Size for Bacterial Cells, By Country, 2014–2021 (USD Million)
Table 27 North America: Market Size for Bacterial Cells, By Country, 2014–2021 (USD Million)
Table 28 Global Market Size for Yeast Cells, By Region, 2014–2021 (USD Million)
Table 29 Europe: Market Size for Yeast Cells, By Country, 2014–2021 (USD Million)
Table 30 North America: Market Size for Yeast Cells, By Country, 2014–2021 (USD Million)
Table 31 Global Market Size for Other Cells, By Region, 2014-2021 (USD Million)
Table 32 Europe: Market Size for Other Cells, By Country, 2014–2021 (USD Million)
Table 33 North America: Market Size for Other Cells, By Country, 2014–2021 (USD Million)
Table 34 Global Market Size, By Technology, 2014–2021 (USD Million)
Table 35 Global Wave-Induced Motion Single-Use Bioreactors Market Size, By Region, 2014–2021 (USD Million)
Table 36 Europe: Wave-Induced Motion Single-Use Bioreactors Market Size, By Country, 2014–2021 (USD Million)
Table 37 North America: Wave-Induced Motion Single-Use Bioreactors Market Size, By Country, 2014–2021 (USD Million)
Table 38 Global Stirred Single-Use Bioreactors Market Size, By Region, 2014–2021 (USD Million)
Table 39 Europe: Stirred Single-Use Bioreactors Market Size, By Country, 2014–2021 (USD Million)
Table 40 North America: Stirred Single-Use Bioreactors Market Size, By Country, 2014–2021 (USD Million)
Table 41 Global Single-Use Bubble Column Bioreactors Market Size, By Region, 2014–2021 (USD Million)
Table 42 Europe: Single-Use Bubble Column Bioreactors Market Size, By Country, 2014–2021 (USD Million)
Table 43 North America: Single-Use Bubble Column Bioreactors Market Size, By Country, 2014–2021 (USD Million)
Table 44 Global Other Single-Use Bioreactor Technologies Market Size, By Region, 2014–2021 (USD Million)
Table 45 Europe: Other Single-Use Bioreactor Technologies Market Size, By Country, 2014–2021 (USD Million)
Table 46 North America: Other Single-Use Bioreactor Technologies Market Size, By Country, 2014–2021 (USD Million)
Table 47 Market Size, By Application, 2014–2021 (USD Million)
Table 48 Market Size for Bioproduction, By Region, 2014–2021 (USD Million)
Table 49 North America: Market Size for Bioproduction, By Country, 2014–2021 (USD Million)
Table 50 Europe: Market Size for Bioproduction, By Country, 2014–2021 (USD Million)
Table 51 Market Size for Process Development, By Region, 2014–2021 (USD Million)
Table 52 North America: Market Size for Process Development, By Country, 2014–2021 (USD Million)
Table 53 Europe: Market Size for Process Development, By Country, 2014–2021 (USD Million)
Table 54 Market Size for Research & Development, By Region, 2014–2021 (USD Million)
Table 55 North America: Market Size for Research & Development, By Country, 2014–2021 (USD Million)
Table 56 Europe: Market Size for Research & Development, By Country, 2014–2021 (USD Million)
Table 57 Global Market Size, By End User, 2014–2021 (USD Million)
Table 58 Global Market Size for Biopharmaceutical Manufacturers, By Region, 2014–2021 (USD Million)
Table 59 North America: Market Size for Biopharmaceutical Manufacturers, By Country, 2014–2021 (USD Million)
Table 60 Europe: Market Size for Biopharmaceutical Manufacturers, By Country, 2014–2021 (USD Million)
Table 61 Global Market Size for R&D Departments, By Region, 2014–2021 (USD Million)
Table 62 North America: Market Size for R&D Departments, By Country, 2014–2021 (USD Million)
Table 63 Europe: Market Size for R&D Departments, By Country, 2014–2021 (USD Million)
Table 64 Market Size, By Region, 2014–2021 (USD Million)
Table 65 North America: Market Size, By Country, 2014–2021 (USD Million)
Table 66 North America: Market Size, By Product Type, 2014–2021 (USD Million)
Table 67 North America: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 68 North America: Market Size, By Technology, 2014–2021 (USD Million)
Table 69 North America: Market Size, By Application, 2014–2021 (USD Million)
Table 70 North America: Market Size, By End User, 2014–2021 (USD Million)
Table 71 U.S.: Market Size, By Product Type, 2014–2021 (USD Million)
Table 72 U.S.: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 73 U.S.: Market Size, By Technology, 2014–2021 (USD Million)
Table 74 U.S.: Market Size, By Application, 2014–2021 (USD Million)
Table 75 U.S.: Market Size, By End User, 2014–2021 (USD Million)
Table 76 Canada: Market Size, By Product Type, 2014–2021 (USD Million)
Table 77 Canada: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 78 Canada: Market Size, By Technology, 2014–2021 (USD Million)
Table 79 Canada: Market Size, By Application, 2014–2021 (USD Million)
Table 80 Canada: Market Size, By End User, 2014–2021 (USD Million)
Table 81 Europe: Market Size, By Country, 2014–2021 (USD Million)
Table 82 Europe: Market Size, By Product Type, 2014–2021 (USD Million)
Table 83 Europe: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 84 Europe: Market Size, By Technology, 2014–2021 (USD Million)
Table 85 Europe: Market Size, By Application, 2014–2021 (USD Million)
Table 86 Europe: Market Size, By End User, 2014–2021 (USD Million)
Table 87 U.K.: Market Size, By Product Type, 2014–2021 (USD Million)
Table 88 U.K.: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 89 U.K.: Market Size, By Technology, 2014–2021 (USD Million)
Table 90 U.K.: Market Size, By Application, 2014–2021 (USD Million)
Table 91 U.K.: Market Size, By End User, 2014–2021 (USD Million)
Table 92 Germany: Market Size, By Product Type, 2014–2021 (USD Million)
Table 93 Germany: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 94 Germany: Market Size, By Technology, 2014–2021 (USD Million)
Table 95 Germany: Market Size, By Application, 2014–2021 (USD Million)
Table 96 Germany: Market Size, By End User, 2014–2021 (USD Million)
Table 97 Rest of Europe: Market Size, By Product Type, 2014–2021 (USD Million)
Table 98 Rest of Europe: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 99 Rest of Europe: Market Size, By Technology, 2014–2021 (USD Million)
Table 100 Rest of Europe: Market Size, By Application, 2014–2021 (USD Million)
Table 101 Rest of Europe: Market Size, By End User, 2014–2021 (USD Million)
Table 102 Asia-Pacific: Market Size, By Product Type, 2014–2021 (USD Million)
Table 103 Asia-Pacific: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 104 Asia-Pacific: Market Size, By Technology, 2014–2021 (USD Million)
Table 105 Asia-Pacific: Market Size, By Application, 2014–2021 (USD Million)
Table 106 Asia-Pacific: Market Size, By End User, 2014–2021 (USD Million)
Table 107 RoW: Market Size, By Product Type, 2014–2021 (USD Million)
Table 108 RoW: Market Size, By Type of Cell, 2014–2021 (USD Million)
Table 109 RoW: Market Size, By Technology, 2014–2021 (USD Million)
Table 110 RoW: Market Size, By Application, 2014–2021 (USD Million)
Table 111 RoW: Market Size, By End User, 2014–2021 (USD Million)
Table 112 Product Launches, 2013–2016
Table 113 Acquisitions, 2013–2016
Table 114 Collaborations, 2013–2016
Table 115 Others, 2013 to 2016

List of Figures

Figure 1 Research Design
Figure 2 Single-Use Bioreactor Market: Top Down Approach
Figure 3 Single-Use Bioreactor Market: Bottom-Up Approach
Figure 4 Breakdown of Primary Interviews: By Company Type, Designation, and Region
Figure 5 Data Triangulation Methodology
Figure 6 Market Size, By Product Type, 2016 vs 2021 (USD Million)
Figure 7 Market Size, By Cell Type, 2016 vs 2021 (USD Million)
Figure 8 Market Size, By Technology, 2016 vs 2021 (USD Million)
Figure 9 Market Size, By Application, 2016 vs 2021 (USD Million)
Figure 10 Market Size, By End User, 2016 vs 2021 (USD Million)
Figure 11 Geographical Snapshot: Single-Use Bioreactors Market
Figure 12 Rising Focus on Reducing Operational Costs—A Primary Growth Driver of the Single-Use Bioreactors Market
Figure 13 Mammalian Cells to Account for the Largest Share in 2016
Figure 14 Biopharmaceutical Manufacturers Will Continue to Dominate the Single-Use Bioreactors Market in 2021
Figure 15 Wave-Induced Motion Single-Use Bioreactors are Projected to Be the Fastest-Growing Technology Segment During Forecast Period
Figure 16 APAC Will Be the Fastest-Growing Regional Market During the Forecast Period
Figure 17 Global Single-Use Bioreactors Market: Drivers, Restraints, Opportunities, and Challenges
Figure 18 U.S.: Biologics Going Off-Patent in the Coming Years
Figure 19 Supply Chain: Single-Use Bioreactors Market
Figure 20 Monoclonal Antibodies Segment to Account for the Largest Share of the Single-Use Bioreactors Market in 2016
Figure 21 U.K. to Be the Fastest-Growing Segment of the Single-Use Bioreactors Market for MABS
Figure 22 Europe to Account for the Largest Share of the Single-Use Bioreactors Market for Recombinant Proteins in 2016
Figure 23 U.S. to Account for the Largest Share of the North American Market for Gene-Modified Cells in 2016
Figure 24 Asia-Pacific to Be the Fastest Growing Segment of Single-Use Bioreactors Market for Other Products During the Forecast Period
Figure 25 Global Single-Use Bioreactors Market, By Type of Cell (2016–2021)
Figure 26 Europe is Expected to Account for the Largest Share of the Subs Market for Bacterial Cells in 2016
Figure 27 The U.K. is Expected to Be the Fastest-Growing Country in the European Single-Use Bioreactors Market for Yeast Cells During the Forecast Period
Figure 28 Wave-Induced Motion Subs are Projected to Grow at the Highest CAGR During the Forecast Period
Figure 29 Europe to Dominate the Stirred Single-Use Bioreactors Technology Segment in 2016
Figure 30 The U.K. is Expected to Be the Fastest-Growing Country in the European Single-Use Bubble Column Bioreactors Market During the Forecast Period
Figure 31 Bio production to Account for the Largest Market Share During the Forecast Period
Figure 32 U.S. to Dominate the North American Market for Process Development
Figure 33 Europe to Dominate the Single-Use Bioreactors Market for R&D During the Forecast Period
Figure 34 Biopharmaceutical Manufacturers Form the Largest End-User Segment of the Single-Use Bioreactors Market
Figure 35 Europe to Dominate the Single-Use Bioreactors Market for Biopharmaceutical Manufacturers During the Forecast Period
Figure 36 Geographic Snapshot: Asia-Pacific is Projected to Grow at the Highest Rate During the Forecast Period
Figure 37 Mammalian Cells Segment Will Witness High Growth in the North American and Asia-Pacific Markets
Figure 38 North America: Single-Use Bioreactors Market Snapshot
Figure 39 R&D Segment to Grow at the Highest Rate in the North American Single-Use Bioreactors Applications Market
Figure 40 Biopharmaceutical Manufacturers Segment to Dominate the U.S. Single-Use Bioreactors Market, By End User
Figure 41 Europe: Single-Use Bioreactors Market Snapshot
Figure 42 Monoclonal Antibodies Segment to Account for the Largest Share of the European Single-Use Bioreactors Market, By Product Type
Figure 43 Wave-Induced Motion Sub to Dominate the U.K. Single-Use Bioreactors Market, By Technology
Figure 44 R&D Departments to Witness the Highest Growth in the Single-Use Bioreactors End-Users Market in Germany
Figure 45 Monoclonal Antibodies Segment to Account for the Largest Share of the Asia-Pacific Single-Use Bioreactors Market, By Product Type
Figure 46 Wave-Induced Motion Sub to Dominate the RoW Single-Use Bioreactors Market, By Application
Figure 47 Product Launches Was the Most Widely Adopted Growth Strategy By Market Players Between 2013 & 2016
Figure 48 Battle for Market Share: Product Launches Accounted for the Largest Share of the Overall Growth Strategies Adopted By Players Between 2013 & 2016
Figure 49 Geographic Revenue Mix of the Top Five Market Players
Figure 50 Company Snapshot: Sartorius Stedim Biotech S.A.
Figure 51 Company Snapshot: Merck Millipore
Figure 52 Company Snapshot: GE Healthcare
Figure 53 Company Snapshot: Danaher Corporation
Figure 54 Company Snapshot: Thermo Fisher Scientific, Inc.
Figure 55 Company Snapshot: Parker Hannifin Corporation

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