Organ-On-Chip (OOC) Global Market Opportunities And Strategies To 2023
Table of Contents
1 Organ-On-Chip Market Executive Summary 2
2 Table of Contents 6
3 List of Figures 13
4 List of Tables 14
5 Report Structure 15
6 Introduction 17
6.1. Segmentation By Organ Type 17
6.2. Market Segmentation By Type Application 18
6.3. Market Segmentation By End User 19
6.4. Market Segmentation By Products & Services 19
6.5. Market Segmentation By Type Of Material 20
7 Organ On Chip Market Characteristics 21
7.1. Market Definition 21
7.2. Market Segmentation By Organ Type 22
7.2.1. Lung-On-Chip 22
7.2.2. Heart-On-Chip 22
7.2.3. Liver-On-Chip 22
7.2.4. Intestine-On-Chip 22
7.2.5. Kidney-On-Chip 22
7.2.6. Skin-On-Chip 22
7.2.7. Blood-Brain-Barrier-On-Chip 22
7.2.8. Other Organ Models 23
7.3. Market Segmentation By Application 23
7.3.1. Toxicology Research 23
7.3.2. Drug Discovery 23
7.3.3. Molecular Biology 23
7.3.4. Disease Modelling 23
7.3.5. Food Safety 23
7.3.6. Other Applications 23
7.4. Market Segmentation By End User 24
7.4.1. Biopharmaceutical companies 24
7.4.2. Academics 24
7.4.3. Food & Beverages 24
7.4.4. Other Commercial Industries 24
7.5. Market Segmentation By Products & Services 24
7.5.1. Devices 24
7.5.2. Testing Services 24
7.6. Market Segmentation By Type Of Material 25
7.6.1. Polymer 25
7.6.2. PDMS 25
7.6.3. Glass 25
7.6.4. Silicon 25
7.7. Organs-On-Chips Origin And Significance 26
7.8. Organ-On-Chip Features 27
7.9. OOC Applications 28
7.9.1. Applications Of OOCs In The Healthcare Industry 28
7.9.2. Other Applications Of OOCs 29
8 OOC Market, Product Analysis –Product Examples 30
8.1.1. Technical Description 30
8.1.2. Typical Organ-On-Chip Structure 30
8.1.3. Product Design Materials 31
8.1.4. Product Design Methodologies 31
8.2. OOC Products In The Market 33
8.2.1. New Product Launches 33
8.2.2. Products In The Pipeline 34
9 OOC Market, Value Chain Analysis 35
9.1.1. Organ/Tissue Physiology 35
9.1.2. Microfluidic Chip and Biosensors 35
9.1.3. 3D Cell Culture 36
9.1.4. Gas & Liquid Perfusion 36
9.2. Organ-On-Chip Market – Business Models 38
9.2.1. Academic Universities/Institutes 39
9.2.2. Spin-offs 39
9.2.3. OOC Development Companies 39
9.2.4. Commercial Industries/End-Users 40
9.2.5. Research Organizations 40
9.2.6. OOC Pricing 40
10 Overview Of Organ-Specific Models 41
10.1.1. Lung-On-Chip 41
10.1.2. Heart-On-Chip 42
10.1.3. Liver-On-Chip 43
10.1.4. Intestine-On-Chip 44
10.1.5. Kidney-On-Chip 44
10.1.6. Skin-On-Chip 46
10.1.7. Blood-Brain-Barrier-On-Chip 47
10.1.8. Human-On-Chip 48
11 Traditional Methods Versus Organ On Chip For Drug Discovery 49
12 OOC Market Trends And Strategies 51
12.1.1. Developments In The Testing Of Human Organs-On-Chips 51
12.1.2. Organ-On-Chip Technology In Space 51
12.1.3. Automated Monitoring Of Organs-On-Chips 52
12.1.4. 3D Printing Of Organs-On Chips 52
12.1.5. Manufacturers Tying Up With End-Users To Design Tailor-Made Products 52
12.1.6. Investment In Integration Of Individual Organs-On-Chips Into Humans-On-Chips 53
12.1.7. Strong Focus On Development Of Custom Organs-On-Chips 54
12.1.8. Manufacturers Work On Disease Models To Expedite Drug Testing 54
12.1.9. Rise In The Collaborations Between Organs-On-Chips Manufacturers And Pharmaceutical Companies 55
12.1.10. Increase In Funding To Develop The Organ-On-Chip Platform 55
13 Collaborations, Partnerships And Agreements 56
14 Recent Developments/Research 58
14.1. Pancreas-On-A-Chip 58
14.2. Retina-On-A-Chip 58
14.3. Bronchi-On-A-Chip 58
14.4. Tumor-On-A-Chip 58
14.5. Organ-On-An-Electronic-Chip 59
14.6. Human Spinal Cords On A Chip 59
14.7. Biosensors In Organ-On-A-Chip 59
14.8. Placenta-On-A-Chip 60
14.9. OOCs For Hepatitis B Virus Testing 60
14.10. Blood-Vessel-On-A-Chip 60
14.11. Development Of Chip Technology Through Partnerships And Acquisitions 61
14.12. Growth In Research Grants 61
15 Organ-On-Chip Porter’s Five Forces Analysis 62
16 Organ-On-Chip Unmet Needs 63
16.1. Lack Of Data Supported Evidence 63
16.2. Ease Of Use And Automation 63
16.3. Lack Of Personalized Understanding Of Diseases 63
16.4. Organ Specific Needs 63
16.5. OOC Patents and Publications 63
17 Global OOC Market Size And Growth 64
17.1. Historic Market Growth, Value ($ Million) 64
17.2. Forecast Market Growth, Value ($ Million) 65
18 Global OOC Market Drivers And Restraints 66
18.1. Market Drivers 66
18.1.1. Increasing Demand For Personalized Medicine 66
18.1.2. Growing Need To Minimize Financial Losses Due To Late Stage Drug Failure 66
18.1.3. Substantial Funding Of Public And Private Sources For OOC Start-Ups And Research Groups 67
18.1.4. Adoption Of OOC Technology By Major Pharmaceutical Companies Such As Roche And AstraZeneca Among Many Others 67
18.1.5. Increasing Drug Repurposing Approaches 67
18.1.6. Rising Healthcare Expenditure 68
18.2. Market Restraints 69
18.2.1. High-Costs Associated With OOCs 69
18.2.2. Compatibility Problems May Occur Due To The Lack Of Standardization 69
18.2.3. Limitations Of Polydimethylsiloxane (PDMS), The Most Commonly Used Substrate Material For The Fabrication Of Oocs 70
18.2.4. Resistance In The Adoption And Regulation Of New Medical Options 70
18.2.5. Need For Skilled Resources For The Development Of OOC Technology 70
18.2.6. OOCs Are Not High Throughput To Conduct Multiple Assays 71
18.2.7. Cell Survivability Issues Can Negatively Impact The Market Growth 71
19 OOC Market, Regional Analysis 72
19.1. Global OOC Market, 2019, By Region, Value ($ Million) 72
19.1.1. North America 72
19.1.2. Europe 72
19.1.3. Rest Of The World 73
19.2. Global OOC Market, 2015 – 2023, Historic And Forecast, By Region 74
20 Global OOC Market Segmentation 76
20.1. Global OOC Market, Segmentation By Organ, 2019, Value ($ Million) 76
20.1.1. Multi- Organs On Chip 77
20.1.2. Liver-On- Chip 77
20.1.3. Intestine- On-Chip 77
20.2. Global OOC Market, 2015 - 2023, Historic and Forecast, Segmentation By Organ 78
20.2.1. Liver-On-Chip 79
20.2.2. Multi-Organs On Chip 79
20.2.3. Blood-Brain Barrier (BBB)-On-Chip 79
20.3. Global OOC Market, Segmentation By Application, 2019, Value ($ Million) 80
20.3.1. Toxicology Research 81
20.3.2. Drug Discovery 81
20.3.3. Other Applications 81
20.4. Global OOC Market, 2015 - 2023, Historic and Forecast, Segmentation By Application 82
20.4.1. Drug Discovery segment 82
20.4.2. Toxicology Research segment 83
20.4.3. Other Applications segment 83
20.5. Global OOC Market, Segmentation By End User, 2019, Value ($ Million) 84
20.5.1. Biopharmaceutical Companies 84
20.5.2. Academics 85
20.5.3. Food & Beverages 85
20.6. Global OOC Market, 2015 - 2023, Historic and Forecast, Segmentation By End User 86
20.6.1. Academics segment 86
20.6.2. Biopharmaceutical Companies segment had 86
20.6.3. Other Commercial Industries segment 87
20.7. Global OOC Market, Segmentation By Products & Services, 2019, Value ($ Million) 88
20.7.1. Devices 88
20.7.2. Testing Services 88
20.8. Global OOC Market, 2015 - 2023, Historic and Forecast, Segmentation By Products & Services 89
20.8.1. Devices 89
20.8.2. Testing Services 89
20.9. Global OOC Market, Segmentation By Type Of Material, 2019, Volume (Kilo Units) 90
20.9.1. Polymer 90
20.9.2. PDMS 90
20.9.3. Silicon 90
20.10. Global OOC Market, 2015 - 2023, Historic and Forecast, Segmentation By Type Of Material 91
20.10.1. Polymer 91
20.10.2. Silicon 91
20.10.3. PDMS 91
21 Global OOC Market Competitive Landscape 92
21.1. Mergers and Acquisitions 94
21.1.1. BioIVT Acquired Ascendance Biotechnology 94
21.2. Company Profiles 95
21.3. Emulate Inc. 95
21.3.1. Company Overview 95
21.3.2. Products And Services 95
21.3.3. Business Strategy 95
21.3.4. Financial Overview 95
21.4. AxoSim Inc. 96
21.4.1. Company Overview 96
21.4.2. Products And Services 96
21.4.3. Business Strategy 96
21.4.4. Financial Overview 96
21.5. Kirkstall 97
21.5.1. Company Overview 97
21.5.2. Products And Services 97
21.5.3. Business Strategy 97
21.5.4. Financial Overview 97
21.6. TissUse GmbH 98
21.6.1. Company Overview 98
21.6.2. Products And Services 98
21.6.3. Business Strategy 98
21.6.4. Financial Overview 98
21.7. Nortis Inc. 99
21.7.1. Company Overview 99
21.7.2. Products And Services 99
21.7.3. Financial Overview 99
21.8. Mimatas BV 100
21.8.1. Company Overview 100
21.8.2. Products And Services 100
21.8.3. Business Strategy 100
21.8.4. Financial Overview 100
22 Global Organ-On-Chip Market – Funding Landscape 101
22.1.1. Funding Landscape – North America 101
22.1.2. Funding Landscape – Europe 105
22.1.3. Funding Landscape – Asia 105
22.1.4. Funding Landscape – ROW 106
23 Global OOC Market Opportunities And Strategies 107
23.1. Global OOC Market In 2023 – Regions Offering Most New Opportunities 107
23.2. Global OOC Market In 2023 – Segments Offering Most New Opportunities 108
23.3. Global Organ-On-Chip Market In 2023- Growth Strategies 111
23.3.1. Market Trend Based Strategies 111
23.3.2. Competitor Strategies 112
24 Conclusions And Recommendations 113
24.1. Conclusions 113
24.2. Recommendations 115
24.2.1. Product 115
24.2.2. Price 115
24.2.3. Place 115
24.2.4. Promotion 116
24.2.5. People 116
25 Appendix 117
25.1. Market Data Sources 117
25.2. Research Methodology 118
25.3. Currencies 119
25.4. Research Inquiries 119
25.5. The Business Research Company 119
25.6. Copyright and Disclaimer 119
List of Tables
Table 1: Global Organ-On-Chip Market, New Product Launches
Table 2: Global Organ-On-Chip Market, Products In The Pipeline
Table 3: Global Organ-On-Chip Market, List Of Universities And Their Spin-offs
Table 4: Limitations Of Traditional Methods Over Organs-On-Chips
Table 5: Global Organ-On-Chip Market, Collaborations, Partnerships And Agreements
Table 6: Global OOC Market, Historic Market Size, 2015 – 2019, $ Million
Table 7: Global OOC Market, Forecast Market Size, 2019 – 2023, $ Million
Table 8: Global OOC Market, 2019, Split By Region
Table 9: Global OOC Market, 2015 – 2023, Historic And Forecast Growth Rate, Split By Region
Table 10: Global OOC Market, Segmentation By Organ, 2019, $ Million
Table 11: Global OOC Market, Historic and Forecast, Segmentation By Organ, 2015-2023
Table 12: Global OOC Market, Segmentation By Application, 2019, $ Million
Table 13: Global OOC Market, Historic and Forecast, Segmentation By Application, 2015-2023
Table 14: Global OOC Market, Segmentation By End User, 2019, $ Million
Table 15: Global OOC Market, Historic and Forecast, Segmentation By End User, 2015-2023
Table 16: Global OOC Market, Segmentation By Products & Services, 2019, $ Million
Table 17: Global OOC Market, Historic and Forecast, Segmentation By Products & Services, 2015-2023
Table 18: Global OOC Market, Segmentation By Type Of Material, 2019, Kilo Units
Table 19: Global OOC Market, Historic and Forecast, Segmentation By Type Of Material, 2015-2023
Table 20: Global OOC Market, Key Competitor Estimated Market Shares, 2018, Percentage (%)
Table 21: Other Major Competitors In The Global OOC Market
Table 22: Global Organ-On-Chip Market, Institutions Funded By NIH, 2017
Table 23: Global Organ-On-Chip Market, Institutions Funded By NCATS For Tissue Chip Testing Centers, 2016
Table 24: Global Organ-On-Chip Market, Institutions Funded By NCATS, 2017
Table 25: Global OOC Market Size Gain ($ Million), 2019 – 2023, By Region
Table 26: Global OOC Market Size Gain ($ Million), 2019 – 2023, Segmentation By Organ
Table 27: Global OOC Market Size Gain ($ Million), 2019 – 2023, Segmentation By Application
Table 28: Global OOC Market Size Gain ($ Million), 2019 – 2023, Segmentation By End User
Table 29: Global OOC Market Size Gain ($ Million), 2019 – 2023, Segmentation By Products & Services
Table 30: Global OOC Market Size Gain (Kilo Units), 2019 – 2023, Segmentation By Type Of Material
Table 31: OOC Market Data Sources
List of Figures
Figure 1: Global Organ-On-Chip Market Segmentation By Organ Type
Figure 2: Global Organ-On-Chip Market Segmentation By Application
Figure 3: Global Organ-On-Chip Market Segmentation By End User
Figure 4: Global Organ-On-Chip Market Segmentation By Products & Services
Figure 5: Global Organ-On-Chip Market Segmentation By Type Of Material
Figure 6: Global Organ-On-Chip Market, Typical Organ-On-Chip Structure
Figure 7: Global Organ-On-Chip Market, Simplified Synopsis of Value Chain Analysis
Figure 8: Global Organ-On-Chip Market, OOC Players Positioning Along The Value Chain
Figure 9: Global Organ-On-Chip Market, Supply Chain Analysis
Figure 10: Global Organ-On-Chip Market, Typical Business Model Of OOC Companies
Figure 11: Global Organ-On-Chip Market, Lung-On-Chip Model
Figure 12: Global Organ-On-Chip Market, Heart-On-Chip Model
Figure 13: Global Organ-On-Chip Market, Liver-On-Chip Model
Figure 14: Global Organ-On-Chip Market, Intestine-On-Chip Model
Figure 15: Global Organ-On-Chip Market, Kidney-On-Chip Model
Figure 16: Global Organ-On-Chip Market, Skin-On-Chip Model
Figure 17: Global Organ-On-Chip Market, Blood-Brain-Barrier-On-Chip Model
Figure 18: Global Organ-On-Chip Market, Human-On-Chip Model
Figure 19: Global Organ-On-Chip Market, Porter’s Five Forces Analysis
Figure 20: Global OOC Market, Historic Market Size, 2015 – 2019, $ Million
Figure 21: Global OOC Market, Forecast Market Size, 2019 – 2023, $ Million
Figure 22: Global OOC Market, 2019, Split By Region
Figure 23: Global OOC Market, 2015 – 2023, Historic And Forecast Growth Rate, Split By Region
Figure 24: Global OOC Market, Segmentation By Organ, 2019, $ Million
Figure 25: Global OOC Market, Historic and Forecast, Segmentation By Organ, 2015-2023
Figure 26: Global OOC Market, Segmentation By Application, 2019, $ Million
Figure 27: Global OOC Market, Historic and Forecast, Segmentation By Application, 2015-2023
Figure 28: Global OOC Market, Segmentation By End User, 2019, $ Million
Figure 29: Global OOC Market, Historic and Forecast, Segmentation By End User, 2015-2023
Figure 30: Global OOC Market, Segmentation By Products & Services, 2019, $ Million
Figure 31: Global OOC Market, Historic and Forecast, Segmentation By Products & Services, 2015-2023
Figure 32: Global OOC Market, Segmentation By Type Of Material, 2019, Kilo Units
Figure 33: Global OOC Market, Historic and Forecast, Segmentation By Type Of Material, 2015-2023
Figure 34: Global OOC Market, Key Competitor Estimated Market Shares, 2018, Percentage (%)
Figure 35: Global Organ-On-Chip Market Funding Landscape Split By Regions, 2015-2017, Value, ($ million)
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