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Neuromodulation Market – [Spinal Cord Stimulation (SCS), Vagus Nerve Stimulation (VNS), Gastric Electrical Stimulation (GES), Deep Brain Stimulation (DBS), Sacral Nerve Stimulation (SNS) & Transcranial Magnetic Stimulation (TMS)] – Forecasts to 2017

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Date: 16-Jan-2013
No. of pages: 193
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Neuromodulation devices have emerged as one of the fastest growing segments of the medical device market due to high demand for minimally invasive and non–invasive treatment. With advancements in technology, neuromodulation is expected to become a promising therapeutic area and high growth industry in the next decade, as it offers symptomatic relief mainly from chronic pain, incontinence, heart failure, headache, depression, epilepsy, etc. The neuromodulation devices market includes deep brain stimulation, spinal cord stimulation, vagus nerve stimulation, sacral nerve stimulation and others external stimulation devices such as transcranial magnetic stimulation, and transcutaneous electrical nerve stimulation (TENS).

The neuromodulation technique acts directly upon nerves or the target area where the activity of nerves is altered due to biological responses produced by electrical stimulation or drug infusion. These devices include small electrodes that are attached to the brain, the spinal cord, or peripheral nerves. These precisely placed leads are connected by means of an extension cable to a pulse generator to generate electrical stimulation. Neuromodulation can have applications in any area of the body and can treat several diseases like chronic pain, epilepsy, psychiatric disorder, movement disorder, cardiovascular disorder, genitourinary and colorectal disorder, stroke and brain injury, and gastric disorder.

The main drivers for the neuromodulation market are the rising population of aged people and age-related diseases like Alzheimer’s, epilepsy, spinal cord injury, and Parkinson’s disease. According to the International Neuromodulation Society, about 40 million to 50 million patients worldwide suffer from epilepsy, and 1.5 million people currently (2012) suffer from Parkinson disease in the U.S. The large pool of patients that suffer from depression, stroke, anxiety disorders, lower back pain, urinary incontinence, and tremor offers the neuromodulation industry opportunities to grow in the next five years. The market for treatment of tinnitus, in particular, represents an emerging application of neuromodulation. According to the American Tinnitus Association, about 50 million people currently (2012) suffer from this disease in the U.S.

This report estimates the market for six major segments, namely, spinal cord stimulation, deep brain stimulation, sacral nerve stimulation, vagus nerve stimulation, gastric electrical stimulation, transcranial magnetic stimulation, and others. The report also estimates the market for different neuromodulation techniques as well as geographic analysis of each segment in North America, Europe, Asia-Pacific, and Rest of the World. As technologies develop and the number of trained physician increases, the likelihood of neuromodulation being seen as life-changing treatment will increase dramatically. It is estimated that the market for neuromodulation will be shared largely by deep brain stimulation and spinal cord stimulation.

The key players in the neuromodulation devices market are Medtronic, Inc. (U.S.), Cyberonics, Inc. (U.S.), Boston Scientific Corporation (U.S.), St. Jude Medical (U.S.), Enteromedics, Inc (U.S.), Neuropace, Inc (U.S.), Zynex, Inc (U.S.) and Neuronetics, Inc (U.S.). The emerging players in this market are Functional Neuromodulation, Ltd (U.S.), Microtransponder (U.S.), and Neurosigma, Inc (U.S.).

Scope of the Report

The research report categorizes the global neuromodulation devices market by procedure, technology, and application. These markets are broken down into segments and sub-segments, providing exhaustive value-volume analysis for 2010, 2011, and 2012 as well as forecast up to 2017. Each market is also analyzed by geography (North America, Europe, Asia-Pacific, and Rest of the World to provide in-depth information on the global scenario.

Global Neurostimulation Devices Market, by Procedure:

  • Internal Neurostimulation
    • Spinal Cord Stimulation (SCS)
      • Failed Back Surgery Syndrome
      • Chronic Pain
      • Ischemic Pain
      • Others
    • Deep Brain Stimulation (DBS)
      • Movement Disorders
        • Parkinson’s  Disease
        • Alzheimer’s Disease
        • Dystonia
        • Tourette’s Syndrome
        • Others
      • Chronic Pain
      • Depression
      • Post-Traumatic Coma
    • Sacral Nerve Stimulation (SNS)
      • Urine Incontinence
      • Fecal Incontinence
    • Vagus Nerve Stimulation (VNS)
      • Epilepsy disease
      • Heart Failure
      • Tinnitus
      • Others
    • Gastric Electrical Stimulation (GES)
      • Gastroparesis
      • Others
  • External Neurostimulation
    • Transcranial Magnetic Stimulation (TMS)
      • Depression
      • Tinnitus
      • Migraine
      • Stroke
      • Others
    • Transcutaneous Electrical Nerve Stimulation (TENS)

Global Neurostimulation Devices Market, by Geography

  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World

Neuromodulation Market – [Spinal Cord Stimulation (SCS), Vagus Nerve Stimulation (VNS), Gastric Electrical Stimulation (GES), Deep Brain Stimulation (DBS), Sacral Nerve Stimulation (SNS) & Transcranial Magnetic Stimulation (TMS)] – Forecasts to 2017

Table Of Contents

1 INTRODUCTION
1.1 KEY TAKE-AWAYS
1.2 REPORT DESCRIPTION
1.3 MARKETS COVERED
1.4 RESEARCH METHODOLOGY
1.4.1 MARKET SIZE
1.4.2 MARKET SHARE
1.4.3 KEY DATA POINTS FROM SECONDARY SOURCES
1.4.4 KEY DATA POINTS FROM PRIMARY SOURCES
1.4.5 ASSUMPTIONS
1.5 STAKEHOLDERS

2 EXECUTIVE SUMMARY

3 MARKET OVERVIEW
3.1 INTRODUCTION
3.2 MARKET SEGMENTATION
3.3 MARKET DYNAMICS
3.3.1 DRIVERS
3.3.1.1 INCREASING INCIDENCE OF NEUROLOGICAL DISORDERS TO SPUR MARKET GROWTH
3.3.1.2 UNPRECEDENTED GLOBAL AGING TO FUEL MARKET GROWTH
3.3.1.3 STRONG PRODUCT PIPELINE TO PROPEL THE MARKET
3.3.1.4 EXPANDED TARGET APPLICATIONS AND NEW INDICATIONS ARE EXPECTED TO STIMULATE GROWTH OF NEUROMODULATION DEVICES
3.3.1.5 INVESTMENTS AND FUNDS – AN IMPETUS FOR MARKET GROWTH
3.4 RESTRAINTS
3.4.1.1 AN UNFAVOURABLE REIMBURSEMENT SCENARIO HINDERS MARKET GROWTH
3.4.1.2 LACK OF TRAINED PROFESSIONALS LIKELY TO HAMPER MARKET GROWTH
3.5 MARKET SHARE ANALYSIS

4 GLOBAL NEUROMODULATION MARKET (INTERNAL & EXTERNAL)
4.1 INTRODUCTION
4.2 INTERNAL STIMULATION
4.2.1 SPINAL CORD STIMULATION (SCS) MARKET
4.2.1.1 MAJOR APPLICATIONS
4.2.1.1.1 FAILED BACK SURGERY SYNDROME
4.2.1.1.2 CHRONIC PAIN
4.2.1.1.3 ISCHEMIA
4.2.2 DEEP BRAIN STIMULATION (DBS)
4.2.2.1 MAJOR APPLICATIONS
4.2.2.1.1 PARKINSON’S DISEASE
4.2.2.1.2 DYSTONIA
4.2.2.1.3 TREMOR
4.2.2.1.4 ALZHEIMER’S
4.2.3 SACRAL NERVE STIMULATION (SNS)
4.2.3.1 MAJOR APPLICATIONS
4.2.3.1.1 URINE INCONTINENCE
4.2.3.1.2 FECAL INCONTINENCE
4.2.4 VAGUS NERVE STIMULATION (VNS)
4.2.4.1 MAJOR APPLICATIONS
4.2.4.1.1 EPILEPSY
4.2.4.1.2 OTHERS
4.2.5 GASTRIC ELECTRICAL STIMULATION (GES)
4.3 EXTERNAL STIMULATION
4.3.1 TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS)
4.3.2 TRANSCRANIAL MAGNETIC STIMULATION (TMS)

5 GEOGRAPHIC ANALYSIS
5.1 INTRODUCTION
5.2 NORTH AMERICA
5.3 EUROPE
5.4 ASIA
5.5 REST OF THE WORLD

6 COMPETITIVE LANDSCAPE
6.1 INTRODUCTION
6.2 AGREEMENTS, PARTNERSHIPS, COLLABORATIONS, CONTRACTS & JOINT VENTURES
6.3 NEW PRODUCT LAUNCH
6.4 EXPANSION
6.5 OTHER DEVELOPMENTS
6.6 APPROVALS

7 COMPANY PROFILES (OVERVIEW, FINANCIALS, PRODUCTS & SERVICES, STRATEGY, & DEVELOPMENTS)*
7.1 ANM ADAPTIVE NEUROMODULATION GMBH
7.2 BIOCONTROL MEDICAL, LTD.
7.3 BOSTON SCIENTIFIC CORPORATION
7.4 CERBOMED GMBH
7.5 CYBERONICS, INC.
7.6 ENDOSTIM, INC.
7.7 ENTEROMEDICS, INC.
7.8 THE MAGSTIM COMPANY LIMITED
7.9 MEDTRONIC, INC.
7.10 NEURONETICS, INC.
7.11 NEUROPACE, INC.
7.12 NEUROSIGMA, INC.
7.13 NEVRO CORPORATION
7.14 RS MEDICAL
7.15 SPINAL MODULATION, INC.
7.16 ST. JUDE MEDICAL
7.17 SYNAPSE BIOMEDICAL, INC.
7.18 UROPLASTY, INC.
7.19 ZYNEX, INC.

List Of Tables

TABLE 1 GLOBAL NEUROMODULATION MARKET, BY PROCEDURE,2010 – 2017 ($MILLION)
TABLE 2 GLOBAL NEUROMODULATION MARKET, BY MODALITY,2010 – 2017 ($MILLION)
TABLE 3 SPINAL CORD STIMULATION MARKET, BY GEOGRAPHY,2010 – 2017 ($MILLION)
TABLE 4 SPINAL CORD STIMULATION MARKET VOLUME, BY GEOGRAPHY,2010 – 2017 (NO OF UNITS)
TABLE 5 GLOBAL SPINAL CORD STIMULATION MARKET, BY APPLICATION,2010 – 2017 ($MILLION)
TABLE 6 DEEP BRAIN STIMULATION MARKET, BY GEOGRAPHY,2010 – 2017 ($MILLION)
TABLE 7 DEEP BRAIN STIMULATION MARKET VOLUME, BY GEOGRAPHY,2010-2017 (NO OF UNITS)
TABLE 8 GLOBAL DEEP BRAIN STIMULATION MARKET, BY APPLICATION,2010 – 2017 ($MILLION)
TABLE 9 SACRAL NERVE STIMULATION MARKET, BY GEOGRAPHY,2010 – 2017 ($MILLION)
TABLE 10 SACRAL NERVE STIMULATION MARKET VOLUME, BY GEOGRAPHY,2010 – 2017 (NO OF UNITS)
TABLE 11 GLOBAL SACRAL NERVE STIMULATION MARKET, BY APPLICATION,2010 – 2017 ($MILLION)
TABLE 12 VAGUS NERVE STIMULATION MARKET, BY GEOGRAPHY,2010 – 2017 ($MILLION)
TABLE 13 VAGUS NERVE STIMULATION MARKET VOLUME, BY GEOGRAPHY,2010 – 2017 (NO OF UNITS)
TABLE 14 GLOBAL VAGUS NERVE STIMULATION MARKET, BY APPLICATION,2010 – 2017 ($MILLION)
TABLE 15 GASTRIC ELECTRICAL STIMULATION MARKET, BY GEOGRAPHY,2010 – 2017 ($MILLION)
TABLE 16 GASTRIC ELECTRICAL STIMULATION MARKET VOLUME,BY GEOGRAPHY, 2010 – 2017 (NO OF UNITS)
TABLE 17 GLOBAL GASTRIC ELECTRICAL STIMULATION MARKET,BY APPLICATION, 2010-2017 ($MILLION)
TABLE 18 TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION MARKET,BY GEOGRAPHY, 2010 – 2017($MILLION)
TABLE 19 TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION MARKET VOLUME, BY GEOGRAPHY, 2010 – 2017 (NO OF UNITS)
TABLE 20 TRANSCRANIAL MAGNETIC STIMULATION MARKET, BY GEOGRAPHY, 2010 – 2017 ($MILLION)
TABLE 21 TRANSCRANIAL MAGNETIC STIMULATION MARKET VOLUME,BY GEOGRAPHY, 2010 – 2017 (NO OF UNITS)
TABLE 22 GLOBAL TRANSCRANIAL MAGNETIC STIMULATION MARKET,BY APPLICATION, 2010 – 2017 ($MILLION)
TABLE 23 NEUROMODULATION DEVICES MARKET, BY GEOGRAPHY,2010 – 2017 ($MILLION)
TABLE 24 EXTERNAL NEUROMODULATION DEVICES MARKET, BY GEOGRAPHY, 2010 – 2017 ($MILLION)
TABLE 25 INTERNAL NEUROMODULATION DEVICES MARKET, BY GEOGRAPHY, 2010 – 2017 ($MILLION)
TABLE 26 GLOBAL EXTERNAL NEUROMODULATION MARKET, BY MODALITY,2010 – 2017 ($MILLION)
TABLE 27 GLOBAL EXTERNAL NEUROMODULATION DEVICES MARKET VOLUME,BY MODALITY, 2010 – 2017 (NO OF UNITS)
TABLE 28 NORTH AMERICA: NEUROMODULATION DEVICES MARKET,BY PROCEDURE, 2010 – 2017 ($MILLION)
TABLE 29 NORTH AMERICA: INTERNAL NEUROMODULATION DEVICES MARKET, BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 30 NORTH AMERICA: INTERNAL NEUROMODULATION DEVICES MARKET VOLUME, BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 31 NORTH AMERICA: EXTERNAL NEUROMODULATION DEVICES MARKET, BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 32 NORTH AMERICA: EXTERNAL NEUROMODULATION DEVICES MARKET VOLUME, BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 33 NORTH AMERICA: SPINAL CORD STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 34 NORTH AMERICA: DEEP BRAIN STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 35 NORTH AMERICA: SACRAL NERVE STIMULATION, BY COUNTRY,2010 – 2017 ($MILLION)
TABLE 36 NORTH AMERICA: VAGUS NERVE STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 37 NORTH AMERICA: GASTRIC ELECTRICAL STIMULATION MARKET,BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 38 NORTH AMERICA: TRANSCRANIAL MAGNETIC STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 39 NORTH AMERICA: TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 40 EUROPE: NEUROMODULATION DEVICES MARKET, BY PROCEDURE,2010 – 2017 ($MILLION)
TABLE 41 EUROPE: INTERNAL NEUROMODULATION DEVICES MARKET,BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 42 EUROPE: INTERNAL NEUROMODULATION DEVICES MARKET VOLUME, BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 43 EUROPE: EXTERNAL NEUROMODULATION DEVICES MARKET,BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 44 EUROPE: EXTERNAL NEUROMODULATION DEVICES MARKET VOLUME, BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 45 EUROPE: SPINAL CORD STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 46 EUROPE: DEEP BRAIN STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 47 EUROPE: SACRAL NERVE STIMULATION, BY REGION,2010 – 2017 ($MILLION)
TABLE 48 EUROPE: VAGUS NERVE STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 49 EUROPE: GASTRIC ELECTRICAL STIMULATION MARKET, BY REGION, 2010 – 2017 ($MILLION)
TABLE 50 EUROPE: TRANSCRANIAL MAGNETIC STIMULATION MARKET,BY REGION, 2010 – 2017 ($MILLION)
TABLE 51 EUROPE: TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION MARKET, BY REGION, 2010 – 2017 ($MILLION)
TABLE 52 ASIA: NEUROMODULATION DEVICES MARKET, BY PROCEDURE,2010 – 2017 ($MILLION)
TABLE 53 ASIA: INTERNAL NEUROMODULATION DEVICES MARKET, BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 54 ASIA: INTERNAL NEUROMODULATION DEVICES MARKET VOLUME,BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 55 ASIA: EXTERNAL NEUROMODULATION DEVICES MARKET,BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 56 ASIA: EXTERNAL NEUROMODULATION DEVICES MARKET VOLUME,BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 57 ASIA: SPINAL CORD STIMULATION MARKET, BY COUNTRY,2010 – 2017 ($MILLION)
TABLE 58 ASIA: DEEP BRAIN STIMULATION MARKET, BY COUNTRY,2010 – 2017 ($MILLION)
TABLE 59 ASIA: SACRAL NERVE STIMULATION, BY COUNTRY,2010 – 2017 ($MILLION)
TABLE 60 ASIA: TRANSCRANIAL MAGNETIC STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 61 ASIA: TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION MARKET, BY COUNTRY, 2010 – 2017 ($MILLION)
TABLE 62 ROW: NEUROMODULATION DEVICES MARKET, BY PROCEDURE,2010 – 2017 ($MILLION)
TABLE 63 ROW: INTERNAL NEUROMODULATION DEVICES MARKET, BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 64 ROW: INTERNAL NEUROMODULATION DEVICES MARKET VOLUME,BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 65 ROW: EXTERNAL NEUROMODULATION DEVICES MARKET,BY MODALITY, 2010 – 2017 ($MILLION)
TABLE 66 ROW: EXTERNAL NEUROMODULATION DEVICES MARKET VOLUME,BY MODALITY, 2010 – 2017 (NO. OF UNITS)
TABLE 67 ROW: SPINAL CORD STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 68 ROW: DEEP BRAIN STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 69 ROW: SACRAL NERVE STIMULATION, BY REGION,2010 – 2017 ($MILLION)
TABLE 70 ROW: VAGUS NERVE STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 71 ROW: GASTRIC ELECTRICAL STIMULATION MARKET, BY REGION,2010 – 2017 ($MILLION)
TABLE 72 ROW: TRANSCRANIAL MAGNETIC STIMULATION MARKET, BY REGION, 2010 – 2017 ($MILLION)
TABLE 73 ROW: TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION MARKET, BY REGION, 2010 – 2017 ($MILLION)
TABLE 74 AGREEMENTS, PARTNERSHIPS, COLLABORATIONS, CONTRACTS & JOINT VENTURES, 2010 – 2012
TABLE 75 NEW PRODUCT LAUNCH, 2010 – 2012
TABLE 76 EXPANSION, 2010 – 2012
TABLE 77 OTHER DEVELOPMENTS, 2010 – 2012
TABLE 78 APPROVALS, 2010 – 2012
TABLE 79 BOSTON SCIENTIFIC CORPORATION: TOTAL REVENUE AND R&D EXPENDITURE, 2009 – 2011 ($MILLION)
TABLE 80 BOSTON SCIENTIFIC CORPORATION: TOTAL REVENUE, BY SEGMENTS, 2009 – 2011 ($MILLION)
TABLE 81 BOSTON SCIENTIFIC: TOTAL REVENUE, BY GEOGRAPHY,2009 – 2011 ($MILLION)
TABLE 82 CYBERONICS, INC.: TOTAL REVENUE AND R&D EXPENDITURE,2009 – 2011 ($MILLION)
TABLE 83 CYBERONICS, INC.: TOTAL REVENUE, BY GEOGRAPHY,2009 – 2011 ($MILLION)
TABLE 84 MEDTRONIC, INC.: TOTAL REVENUE AND R&D EXPENDITURE,2009 – 2011 ($MILLION)
TABLE 85 MEDTRONIC, INC: TOTAL REVENUE, BY SEGMENTS,2009 – 2011 ($MILLION)
TABLE 86 MEDTRONIC, INC.: TOTAL REVENUE, BY GEOGRAPHY,2009 – 2011 ($MILLION)
TABLE 87 ST. JUDE MEDICAL, INC: TOTAL REVENUE AND R&D EXPENDITURE, 2009 – 2011 ($MILLION)
TABLE 88 ST. JUDE MEDICAL, INC: TOTAL REVENUE, BY SEGMENTS,2009 – 2011 ($MILLION)
TABLE 89 ST. JUDE MEDICAL, INC: TOTAL REVENUE, BY GEOGRAPHY,2009 – 2011 ($MILLION)
TABLE 90 UROPLASTY, INC.: TOTAL REVENUE AND R&D EXPENDITURE,2010-2012 ($MILLION)
TABLE 91 UROPLASTY, INC.: TOTAL REVENUE, BY GEOGRAPHY,2010 – 2012 ($MILLION)
TABLE 92 ZYNEX, INC.: TOTAL REVENUE AND R&D EXPENDITURE,2009 – 2011 ($MILLION)
TABLE 93 ZYNEX, INC.: TOTAL REVENUE, BY SEGMENTS,2009 – 2011 ($MILLION)

List Of Figures

FIGURE 1 NEUROMODULATION MARKET SEGMENTATION
FIGURE 2 MARKET DYNAMICS
FIGURE 3 NEUROMODULATION MARKET SHARE ANALYSIS, BY REVENUE, 2011
FIGURE 4 KEY GROWTH STRATEGIES, 2010 – 2012

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