Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Pipeline Review, H1 2016

Publisher Name :
Date: 27-Apr-2016
No. of pages: 65

Global Markets Direct's, ‘Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Pipeline Review, H1 2016', provides in depth analysis on Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) targeted pipeline therapeutics.

The report provides comprehensive information on the Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) targeted therapeutics development and features dormant and discontinued projects.

Global Markets Direct's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

  • The report provides a snapshot of the global therapeutic landscape for Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119)

  • The report reviews Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

  • The report reviews key players involved in Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) targeted therapeutics and enlists all their major and minor projects

  • The report assesses Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

  • The report summarizes all the dormant and discontinued pipeline projects

  • The report reviews latest news and deals related to Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) targeted therapeutics

Reasons to buy

  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

  • Identify and understand the targeted therapy areas and indications for Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119)

  • Identify the use of drugs for target identification and drug repurposing

  • Identify potential new clients or partners in the target demographic

  • Develop strategic initiatives by understanding the focus areas of leading companies

  • Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics

  • Devise corrective measures for pipeline projects by understanding Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) development landscape

  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Pipeline Review, H1 2016

Table of Contents

Table of Contents 2
List of Tables 6
List of Figures 6
Introduction 7
Global Markets Direct Report Coverage 7
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) Overview 8
Therapeutics Development 9
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Products under Development by Stage of Development 9
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Products under Development by Therapy Area 10
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Products under Development by Indication 11
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Pipeline Products Glance 12
Late Stage Products 12
Early Stage Products 13
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Products under Development by Companies 14
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Products under Development by Universities/Institutes 16
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Therapeutics Assessment 18
Assessment by Monotherapy/Combination Products 18
Assessment by Mechanism of Action 19
Assessment by Route of Administration 20
Assessment by Molecule Type 21
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Companies Involved in Therapeutics Development 22
Amgen Inc. 22
Array BioPharma Inc. 23
Astellas Pharma Inc. 24
CymaBay Therapeutics, Inc. 25
Daiichi Sankyo Company, Limited 26
F. Hoffmann-La Roche Ltd. 27
GlaxoSmithKline Plc 28
Hyundai Pharmaceutical Co., Ltd. 29
LG Life Science LTD. 30
Merck & Co., Inc. 31
Neurocrine Biosciences, Inc. 32
Novartis AG 33
Rhizen Pharmaceuticals S.A. 34
Sanwa Kagaku Kenkyusho Co., Ltd. 35
Takeda Pharmaceutical Company Limited 36
Yuhan Corporation 37
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Drug Profiles 38
17-i - Drug Profile 38
Product Description 38
Mechanism Of Action 38
R&D Progress 38
ARRY-981 - Drug Profile 39
Product Description 39
Mechanism Of Action 39
R&D Progress 39
AS-1669058 - Drug Profile 40
Product Description 40
Mechanism Of Action 40
R&D Progress 40
DA-1241 - Drug Profile 41
Product Description 41
Mechanism Of Action 41
R&D Progress 41
DS-8500 - Drug Profile 42
Product Description 42
Mechanism Of Action 42
R&D Progress 42
GSK-2041706 - Drug Profile 43
Product Description 43
Mechanism Of Action 43
R&D Progress 43
HD-0471042 - Drug Profile 44
Product Description 44
Mechanism Of Action 44
R&D Progress 44
HD-0471953 - Drug Profile 45
Product Description 45
Mechanism Of Action 45
R&D Progress 45
HOB-047 - Drug Profile 46
Product Description 46
Mechanism Of Action 46
R&D Progress 46
KR-69318 - Drug Profile 47
Product Description 47
Mechanism Of Action 47
R&D Progress 47
LC-34AD3 - Drug Profile 48
Product Description 48
Mechanism Of Action 48
R&D Progress 48
MBX-2982 - Drug Profile 49
Product Description 49
Mechanism Of Action 49
R&D Progress 49
Small Molecule to Agonize GPR-119 for Type 2 Diabetes - Drug Profile 50
Product Description 50
Mechanism Of Action 50
R&D Progress 50
Small Molecule to Agonize GPR119 for Type 2 Diabetes - Drug Profile 51
Product Description 51
Mechanism Of Action 51
R&D Progress 51
Small Molecule to Agonize GPR119 for Type II Diabetes - Drug Profile 52
Product Description 52
Mechanism Of Action 52
R&D Progress 52
Small Molecule to Agonize GPR119 for Undisclosed Indication - Drug Profile 53
Product Description 53
Mechanism Of Action 53
R&D Progress 53
Small Molecule to Agonize GPR119 Receptor for Undisclosed Indication - Drug Profile 54
Product Description 54
Mechanism Of Action 54
R&D Progress 54
Small Molecules to Agonize GPR119 for Metabolic Disorders - Drug Profile 55
Product Description 55
Mechanism Of Action 55
R&D Progress 55
Small Molecules to Agonize GPR119 for Type 2 Diabetes - Drug Profile 56
Product Description 56
Mechanism Of Action 56
R&D Progress 56
Small Molecules to Agonize GPR119 for Type II Diabetes - Drug Profile 57
Product Description 57
Mechanism Of Action 57
R&D Progress 57
Small Molecules to Agonize GPR119 Receptor for Type 2 Diabetes - Drug Profile 58
Product Description 58
Mechanism Of Action 58
R&D Progress 58
YH-18420 - Drug Profile 59
Product Description 59
Mechanism Of Action 59
R&D Progress 59
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Dormant Projects 60
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Discontinued Products 61
Glucose-Dependent Insulinotropic Receptor (G-Protein Coupled Receptor 119 or GPR119) - Featured News & Press Releases 62
Nov 05, 2009: Metabolex Closes $8.6 Million Financing Round 62
Nov 12, 2008: Metabolex Announces Positive Results From Phase 1a Clinical Trial Of MBX-2982 62
Mar 26, 2008: Metabolex, Inc. Initiates Phase 1 Trial Of MBX-2982 63
Appendix 64
Methodology 64
Coverage 64
Secondary Research 64
Primary Research 64
Expert Panel Validation 64
Contact Us 64
Disclaimer 65

List of Tables

Number of Products under Development for, H1 2016 9
Number of Products under Development by Therapy Area, H1 2016 10
Number of Products under Development by Indication, H1 2016 11
Comparative Analysis by Late Stage Development, H1 2016 12
Comparative Analysis by Early Stage Products, H1 2016 13
Number of Products under Development by Companies, H1 2016 14
Products under Development by Companies, H1 2016 15
Number of Products under Investigation by Universities/Institutes, H1 2016 16
Products under Investigation by Universities/Institutes, H1 2016 17
Assessment by Monotherapy/Combination Products, H1 2016 18
Number of Products by Stage and Mechanism of Action, H1 2016 19
Number of Products by Stage and Route of Administration, H1 2016 20
Number of Products by Stage and Molecule Type, H1 2016 21
Pipeline by Amgen Inc., H1 2016 22
Pipeline by Array BioPharma Inc., H1 2016 23
Pipeline by Astellas Pharma Inc., H1 2016 24
Pipeline by CymaBay Therapeutics, Inc., H1 2016 25
Pipeline by Daiichi Sankyo Company, Limited, H1 2016 26
Pipeline by F. Hoffmann-La Roche Ltd., H1 2016 27
Pipeline by GlaxoSmithKline Plc, H1 2016 28
Pipeline by Hyundai Pharmaceutical Co., Ltd., H1 2016 29
Pipeline by LG Life Science LTD., H1 2016 30
Pipeline by Merck & Co., Inc., H1 2016 31
Pipeline by Neurocrine Biosciences, Inc., H1 2016 32
Pipeline by Novartis AG, H1 2016 33
Pipeline by Rhizen Pharmaceuticals S.A., H1 2016 34
Pipeline by Sanwa Kagaku Kenkyusho Co., Ltd., H1 2016 35
Pipeline by Takeda Pharmaceutical Company Limited, H1 2016 36
Pipeline by Yuhan Corporation, H1 2016 37
Dormant Projects, H1 2016 60
Discontinued Products, H1 2016 61

List of Figures

Number of Products under Development for, H1 2016 9
Number of Products under Development by Therapy Area, H1 2016 10
Number of Products under Development by Top 10 Indication, H1 2016 11
Comparative Analysis by Early Stage Products, H1 2016 13
Assessment by Monotherapy/Combination Products, H1 2016 18
Number of Products by Stage and Mechanism of Actions, H1 2016 19
Number of Products by Stage and Routes of Administration, H1 2016 20
Number of Products by Stage and Molecule Type, H1 2016 21
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