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KLH, which can be used as an active pharmaceutical ingredient ("API"), is a very large, high molecular weight, oxygen-carrying glycoprotein made of millions of atoms. There are two KLH subunit forms, KLH1 and KLH2, each composed of seven or eight functional units, with each functional unit having an oxygen binding site of two copper atoms. Keyhole limpet hemocyanin is an extremely large, heterogeneous glycosylated protein consisting of subunits with a molecular weight of 350,000 and 390,000 in aggregates with molecular weights of 4,500,000-13,000,000. Each domain of a KLH subunit contains two copper atoms that together bind a single oxygen molecule (O2). The KLH protein is potently immunogenic yet safe in humans and is therefore highly prized as a vaccine carrier protein.
KLH protein is derived only from the hemolymph of the giant keyhole limpet (megathura crenulata), which is native only to a limited stretch of the Pacific Ocean coastline along Southern California and Baja California, Mexico.
Scope of the Report:
This report focuses on the Keyhole Limpet Hemocyanin (KLH) in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
Megathura crenulata is native to rocky coasts of Southern California, United States to Baja California, Mexico and are found at shallow depths below the low tide line. American companies dominate the keyhole limpet hemocyanin product market. But downstream demand of keyhole limpet hemocyanin mainly is concentrated in Europe. Owning to immature technology, there is no company in China produce KLH for the time being.
Due to immature technology, keyhole limpet hemocyanin production capacity will not be released quickly in the recent years. However, once some company overcomes technology bottleneck and produces keyhole limpet hemocyanin, the company can achieve preferable gains, that's why many investors are trying hard to enter into the industry currently.
The worldwide market for Keyhole Limpet Hemocyanin (KLH) is expected to grow at a CAGR of roughly 1.2% over the next five years, will reach 9 million US$ in 2023, from 9 million US$ in 2017, according to a new GIR (Global Info Research) study.
Market Segment by Manufacturers, this report covers
- Biosyn Corporation
- Stellar Biotechnologies
- Sigma-Aldrich Fine Chemicals
- Thermo-Fisher Scientific
Market Segment by Regions, regional analysis covers
- North America (United States, Canada and Mexico)
- Europe (Germany, France, UK, Russia and Italy)
- Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
- South America (Brazil, Argentina, Colombia etc.)
- Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
- GMP/Clinic Grade
- Research Grade
Market Segment by Applications, can be divided into
There are 15 Chapters to deeply display the global Keyhole Limpet Hemocyanin (KLH) market.
Chapter 1, to describe Keyhole Limpet Hemocyanin (KLH) Introduction, product scope, market overview, market opportunities, market risk, market driving force;
Chapter 2, to analyze the top manufacturers of Keyhole Limpet Hemocyanin (KLH), with sales, revenue, and price of Keyhole Limpet Hemocyanin (KLH), in 2016 and 2017;
Chapter 3, to display the competitive situation among the top manufacturers, with sales, revenue and market share in 2016 and 2017;
Chapter 4, to show the global market by regions, with sales, revenue and market share of Keyhole Limpet Hemocyanin (KLH), for each region, from 2013 to 2018;
Chapter 5, 6, 7, 8 and 9, to analyze the market by countries, by type, by application and by manufacturers, with sales, revenue and market share by key countries in these regions;
Chapter 10 and 11, to show the market by type and application, with sales market share and growth rate by type, application, from 2013 to 2018;
Chapter 12, Keyhole Limpet Hemocyanin (KLH) market forecast, by regions, type and application, with sales and revenue, from 2018 to 2023;
Chapter 13, 14 and 15, to describe Keyhole Limpet Hemocyanin (KLH) sales channel, distributors, traders, dealers, Research Findings and Conclusion, appendix and data source