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Competent cells are bacteria which can accept extra-chromosomal DNA or plasmids. Cells can be made competent in several ways. One such way is to "shock" it, which involves cooling the bacteria in a Calcium Chloride bath at 0 degrees Celsius, then quickly heating it to around 47 degrees Celsius for approximately 90 seconds (too long will denature the cell membrane, killing the bacteria). The calcium chloride ions neutralize the repulsion between the negatively charged phospholipid heads of the cell membrane and the negatively charged phosphate groups on the DNA. The quick heat shock creates a thermal gradient which, in turn, creates a draft leading into the cell, allowing extra-chromosomal DNA (such as plasmids) to enter the cell, allowing the bacterium to be genetically modifed.
Scope of the Report:
This report studies the Competent Cells market status and outlook of Global and major regions, from angles of players, countries, product types and end industries; this report analyzes the top players in global market, and splits the Competent Cells market by product type and applications/end industries.
Asia-Pacific has the largest global export quantity and manufacturers in Competent Cells market, while the North America is the second sales volume market for Competent Cells in 2016.
In the industry, Merck KGaA profits most in 2016 and recent years, while Thermo Fisher Scientific and Agilent Technologies ranked 2 and 3.The market share of them is 13.28%, 9.52% and 7.00% in 2016.The gap of market share is keep on enlarged due to different strategy.
Nowadays, there are two mainly types of Competent Cells, including Chemically Competent Cells and Electrocompetent Cells. And Chemically Competent Cells is the main type for Competent Cells, and the Chemically Competent Cells reached a sales volume of approximately 42236 K Unit in 2016, with 64.12% of global sales volume.
Competent Cells technology is much mature now, and new enterprises can not surpass existing famous brands on reputation or design in the short term. So, the study group recommends the new entrants need to be considered carefully before enter into this field.
The global Competent Cells market is valued at xx million USD in 2017 and is expected to reach xx million USD by the end of 2023, growing at a CAGR of xx% between 2017 and 2023.
The Asia-Pacific will occupy for more market share in following years, especially in China, also fast growing India and Southeast Asia regions.
North America, especially The United States, will still play an important role which cannot be ignored. Any changes from United States might affect the development trend of Competent Cells.
Europe also play important roles in global market, with market size of xx million USD in 2017 and will be xx million USD in 2023, with a CAGR of xx%.
Market Segment by Companies, this report covers
- Merck KGaA
- Thermo Fisher Scientific
- Agilent Technologies
- Takara Bio
- Promega Corporation
- Beijing TransGen Biotech
- GeneScript Corporation
- Yeastern Biotech
- New England Biolabs
- QIAGEN N.V.
- OriGene Technologies
- Zymo Research
- Bio-Rad Laboratories
- Delphi Genetics
- IBA GmBH
- Cell Applications
- BioDynamics Laboratory
- Scarab Genomics
- GCC Biotech
- SMOBIO Technology
- Edge BioSystems
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
- Chemically Competent Cells
- Electrocompetent Cells
Market Segment by Applications, can be divided into
- Subcloning & Routine Cloning
- Phage Display Library Construction
- Toxic/Unstable DNA Cloning
- High-Throughput Cloning
- Protein Expression
- Single-Stranded DNA Production
- Bacmid creation
- Cre-lox recombination (PIR1/PIR2)