European Market Report for Brachytherapy 2016 - MedCore

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Date: 01-Sep-2016
No. of pages: 96
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Description

The largest percentage of brachytherapy procedures performed that year were performed in Germany. Procedures performed in France, the United Kingdom and Italy were also relatively large, although they all experienced moderate declines in procedural volumes. Spain is expected to experience the greatest growth in procedural numbers over the forecast period. The total market for brachytherapy is expected to remain stable over the forecast period as there is a great effort in Europe, particularly in Germany, to conduct scientific research on the effectiveness of brachytherapy in comparison to external beam radiotherapy. As brachytherapy is the gold-standard method of treating prostate cancer, some urologists may prefer to use this method over more experimental technology due to the accuracy of the treatment.

Abstract

Brachytherapy is an outpatient procedure for the treatment of prostate cancer. In brachytherapy, a needle is inserted through the perineum and radioactive seeds are implanted into the prostate. Fluoroscopy and ultrasound are used to visualize the prostate gland for precise positioning of the needles. There are three types of LDR radioactive seeds: iodine-125, palladium-103 and cesium-131. These radioactive isotopes are left inside the prostate for up to several weeks and ultimately destroy tumor cells by damaging the cells' DNA, diminishing their ability to repair and causing cell death. Because palladium isotopes have a shorter half-life than iodine isotopes, the radiation dosage is delivered over a shorter period of time. For the purposes of this analysis, only iodine seeds will be considered.

Companies


  • Coloplast

  • Wellspect HealthCare

  • Teleflex

  • Hollister

  • C. R. Bard

  • Boston Scientific

  • Karl Storz

  • Olympus

  • Manfred Sauer

  • Lumenis

  • Covidien

  • Richard Wolf

  • Cook Medical

  • Dornier MedTech

  • Eckert & Ziegler BEBIG

  • GE Healthcare (Oncura)


Others include: Ace Medical Devices, Ackermann, Advanced Shockwave Technology, Agency for Medical Innovations (A.M.I.), Allium Medical, Amecath, Apexmed International, Applied Medical, AprioMed, Aspide, Astora, B. Braun, Bactiguard, Best Medical, BioDerm, Biolitec, Boston Scientific, Caldera Medical, CL Medical, Convatec, Convergent Laser Technologies, Cook Medical, Cousin Biotech, Cure Medical, Direx, DynaMesh, EDAP TMS, Electro Medical Systems, Elekta, Ethicon, Helioscopie, IsoAid, Karl Storz, LocaMed, Medispec, MTS Medical, Neomedic International, Olympus, PercSys, Poiesis Medical, Promedon, Quanta Systems, ROCAMED, Siemens, Sopro-Comeg, Stahl Endoscopy, Stryker, Theragenics (BXT Accelyon), Trimedyne, Vygon, Zephyr Surgical Implants, etc.

European Market Report for Brachytherapy 2016 - MedCore

Table of Contents

Table Of Contents I
List Of Figures Xiii
List Of Charts Xvi

Executive Summary 1
European Urological Device Market Overview 1
Competitive Analysis 3
Market Trends 6
Market Developments 8
Markets Included 9
Procedures Included 11
Key Report Updates 12
Version History 12

Research Methodology 13
1.1 Research Scope 13
1.2 Idata's 9-Step Methodology 13
Step 1: Project Initiation & Team Selection 13
Step 2: Prepare Data Systems and Perform Secondary Research 15
Step 3: Preparation for Interviews & Questionnaire Design 16
Step 4: Performing Primary Research 17
Step 5: Research Analysis: Establishing Baseline Estimates 19
Step 6: Market Forecast and Analysis 20
Step 7: Identify Strategic Opportunities 22
Step 8: Final Review and Market Release 23
Step 9: Customer Feedback and Market Monitoring 24

Disease Overview 25
2.1 Basic Anatomy 25
2.1.1 Human Urinary System 25
2.2 URINARY PATHOLOGY AND DISORDERS 26
2.2.1 Benign Prostate Hyperplasia (BPH) 26
2.2.2 Urinary Incontinence 27
2.2.3 Urinary Tract Infections (UTI) 27
2.2.4 Kidney Stones 28
2.2.5 Bladder Prolapse 29
2.2.6 Overactive Bladder 29
2.2.7 Prostatitis 30
2.2.8 Erectile Dysfunction (ED) 30
2.2.9 Cancer 31
2.2.9.1.1 Prostate Cancer 31
2.2.9.1.2 Bladder Cancer 32
2.3 Patient Demographics 34
2.3.1 Benign Prostatic Hyperplasia 34
2.3.2 Urinary Incontinence 34
2.3.3 UTI 35
2.3.4 Kidney Stones 35
2.3.5 Erectile Dysfunction 36
2.3.6 Overactive Bladder 37
2.3.7 Prostatitis 37
2.3.8 Cancer 38
2.3.8.1 Prostate Cancer 38
2.3.8.2 Bladder Cancer 38

Product Assessment 40
3.1 Product Portfolios 40
3.1.1 Brachytherapy 40
3.1.1.1.1 HDR 40
3.1.1.1.2 LDR 41
3.2 Clinical Trials 42
3.2.1 Boston Scientific 43
3.2.2 C.R. Bard 50
3.2.3 Coloplast 56
3.2.4 Dornier MedTech 58
3.2.5 Ethicon 59
3.2.6 GE (Oncura) 60
3.2.7 Hollister 61
3.2.8 Lumenis 62
3.2.9 Olympus 64
3.2.10 Teleflex 65
3.2.11 WellSpect Healthcare 66

Country Profiles 67
4.1 Introduction 67
4.1.1.1 Population 67
4.1.1.2 Median Age 67
4.1.1.3 GDP Per Capita 67
4.1.1.4 Price Index 67
4.2 Germany 69
4.3 France 70
4.4 United Kingdom 71
4.5 Italy 72
4.6 Spain 73
4.7 Benelux 74
4.8 Scandinavia 75
4.9 Austria 76
4.10 Switzerland 77
4.11 Portugal 78

Brachytherapy Market 79
5.1 Introduction 79
5.2 Market Analysis And Forecast 81
5.3 Drivers And Limiters 88
5.3.1 Market Drivers 88
5.3.2 Market Limiters 88
5.4 Competitive Market Share Analysis 90

Abbreviations 94

Appendix Ii: Company Press Releases 96

List of Charts

Chart 1 1: Total Urological Device Market, Europe, 2012 - 2022 2
Chart 1 2: Total Urological Device Market Overview, Europe, 2015 & 2022 2
Chart 4 1: Country Profile, Germany, 2015 69
Chart 4 2: Country Profile, France, 2015 70
Chart 4 3: Country Profile, United Kingdom, 2015 71
Chart 4 4: Country Profile, Italy, 2015 72
Chart 4 5: Country Profile, Spain, 2015 73
Chart 4 6: Country Profile, Benelux, 2015 74
Chart 4 7: Country Profile, Scandinavia, 2015 75
Chart 4 8: Country Profile, Austria, 2015 76
Chart 4 9: Country Profile, Switzerland, 2015 77
Chart 4 10: Country Profile, Portugal, 2015 78
Chart 5 1: Brachytherapy Market, Europe, 2012 - 2022 82
Chart 5 2: Leading Competitors, Brachytherapy Device Market, Europe, 2015 93

List of Figures

Figure 1 1: Urological Device Competitor Market Share Ranking by Segment, Europe, 2015 (1 of 2) 3
Figure 1 2: Urological Device Competitor Market Share Ranking by Segment, Europe, 2015 (2 of 2) 4
Figure 1 3: Companies Mentioned in Report 5
Figure 1 4: Factors Impacting the Urological Device Market by Segment, Europe (1 of 2) 6
Figure 1 5: Factors Impacting the Urological Device Market by Segment, Europe (2 of 2) 7
Figure 1 6: Recent Events in Urological Device Market, Europe, 2012 - 2016 8
Figure 1 7: Urological Device Markets Covered, Europe, 2015, (Part 1 of 2) 9
Figure 1 8: Urological Device Markets Covered, Europe, 2015, (Part 2 of 2) 10
Figure 1 9: Urological Procedures Covered, Europe, 2015 11
Figure 1 10: Key Report Updates 12
Figure 1 11: Version History 12
Figure 3 1: Safety and Effectiveness of Jetstream Atherectomy System (J-SUPREME) 43
Figure 3 2: Investigational Device Evaluation of the WATCHMAN FLX™ LAA Closure Technology (PINNACLE FLX) 43
Figure 3 3: Microparticle Enhanced Cytotoxic Transarterial Embolization Therapy (MIRACLEIII) 44
Figure 3 4: Watchman FLX Left Atrial Appendage Closure Device Post Approval Study 44
Figure 3 5: Expanding MRI Access for Patients With New and Existing ICDs and CRT-Ds ( ENABLE MRI) (ENABLE MRI) 45
Figure 3 6: Observation of ImageReady™ MR Conditional Pacing System in China 45
Figure 3 7: EVOLVE Short DAPT Study 46
Figure 3 8: ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent (IMPERIAL) 46
Figure 3 9: CoverEdge Algorithm Programming Study 47
Figure 3 10: Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement 47
Figure 3 11: The Captivator EMR Registry 48
Figure 3 12: FAST Feasibility Study 48
Figure 3 13: Using the Vessix Renal Denervation System for the Treatment of Hypertension 49
Figure 3 14: A Study to Evaluate the Effect of Precision Spectra™ Programming 49
Figure 3 15: Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft 50
Figure 3 16: Study of Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair 50
Figure 3 17: A Single Arm Trial Evaluating the BARD Lutonix Drug-Coated Balloon 51
Figure 3 18: Korean Post-market Registry Assessing the Clinical Use and Safety of the Lutonix 51
Figure 3 19: A Prospective Trial of a Bio-absorbable Mesh 52
Figure 3 20: A Post-Market, Single-Arm Trial of XenMatrix™ AB Surgical Graft 52
Figure 3 21: BARD® The VENOVO™ Venous Stent Study 53
Figure 3 22: Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft (AVeNEW) 53
Figure 3 23: Time and Motion Related to PICC Insertion Process and Catheter Tip Confirmation 54
Figure 3 24: Prospective Feasibility Trial of AccuCath 2.25" BC 54
Figure 3 25: Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment 55
Figure 3 26: Assessing the Clinical Use of the Lutonix 035 Drug Coated Balloon Catheter 55
Figure 3 27: Investigation of Two New 1-piece Ostomy Products 56
Figure 3 28: Investigation of a New 2-piece Ostomy Product 56
Figure 3 29: Altis® 522 Trial - Treatment of Female Stress Urinary Incontinence 57
Figure 3 30: ARIES for Vasculogenic Erectile Dysfunction 58
Figure 3 31: The EVICEL® Neurosurgery Phase III Study 59
Figure 3 32: Powered Surgical Stapler in VATS Lung Resection Procedures in China 59
Figure 3 33: Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit 60
Figure 3 34: Clinical Evaluation of a Dual Energy CT System 60
Figure 3 35: Assessment of a Oral Endotracheal Tube Fastener 61
Figure 3 36: Utilizing Holmium Laser for FURS Renal Stone Lithotripsy 62
Figure 3 37: Ablation Efficacy of Contact Side Firing Fiber in Predefined Settings for Treating BPH. 62
Figure 3 38: Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD 63
Figure 3 39: Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea 64
Figure 3 40: Evaluation and Control of WAG in PACU Within Patient and Caregiver Breathing Zone 65
Figure 3 41: Evaluation of a Novel Electronic Transanal Irrigation System - Navina™ Smart 66
Figure 5 1: Brachytherapy Market, Europe, 2012 - 2022 (€ and US$) 81
Figure 5 2: Units Sold by Country, Brachytherapy Market, Europe, 2012 - 2022 83
Figure 5 3: Average Selling Price by Country, Brachytherapy Market, Europe, 2012 - 2022 (€) 84
Figure 5 4: Average Selling Price by Country, Brachytherapy Market, Europe, 2012 - 2022 (US$) 85
Figure 5 5: Market Value by Country, Brachytherapy Market, Europe, 2012 - 2022 (€M) 86
Figure 5 6: Market Value by Country, Brachytherapy Market, Europe, 2012 - 2022 (US$M) 87
Figure 5 7: Drivers and Limiters, Brachytherapy Device Market, Europe, 2015 89
Figure 5 8: Leading Competitors, Brachytherapy Device Market, Europe, 2015 92
Figure 7 1: Press Release Summary 97

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