Circulating Tumor Cell (CTC) Diagnostics: Technologies and Global Markets

Publisher Name :
Date: 01-Feb-2022
No. of pages: 157

Report Scope:

The scope of this study involves clinical testing, prognostic and monitoring markets for CTCs in cancer. The report also includes the clinical research segment as well as currently approved CTC tests and their markets. The regulatory environment, current technologies, new technologies, cancer incidence, market projections and market share, along with the latest trends and new developments in this area, are included to support the clinical testing market.

Based on cancer type, the market for circulating tumor cells diagnostics is segmented into breast cancer, colorectal cancer and prostate cancer.

Based on technology, the market for circulating tumor cells diagnostics is segmented into CTC enrichment and detection, CTC direct detection and CTC analysis.

Based on application, the market for circulating tumor cells diagnostics is segmented into clinical/liquid biopsy and research.

The report discusses the qualitative and quantitative factors influencing market growth. Market drivers, restraints and opportunities are discussed in the report.

This report discusses some of the major drivers and restraints in the market for circulating tumor cells diagnostics, and it surveys the competitive landscape as well as the key players' strategies and performances. The discussion is focused on the major market players, trends in product launches, collaborations, and mergers and acquisitions. The report also includes company profiles of major vendors that include a company overview, key product offerings, financial statistics and recent developments. The report provides insights on market shares and upcoming regional demand for circulating tumor cells diagnostics.

Some of the major market players discussed in the report are Qiagen N.V., Biocept Inc., Greiner Bio One International GmbH, Precision Medicine Group LLC and Menarini Silicon Biosystems. For market estimates, data have been provided for the 2020 as the base year, with forecasts for 2021 through 2026. Projected and forecasted revenue values are in constant U.S. dollars that have not been adjusted for inflation.

Report Includes:

- 24 data tables and 49 additional tables

- An up-to-date review and analysis of the global markets for circulating tumor cell (CTC) diagnostics

- Analyses of the global market trends, with data from 2019-2021, and projections of compound annual growth rates (CAGRs) through 2026

- Highlights of the upcoming market opportunities in the CTC diagnostics industry, and areas of focus to forecast this market into various segments and sub-segments

- Evaluation and forecast the global CTC diagnostics market size, forecasted growth trends, and corresponding market share analysis by cancer type, technology, application, and region

- In-depth information concerning market drivers and challenges, latest technologies, breakthrough innovations, costs and benefits of CTC enrichment techniques, regulatory concerns, and clinical trials

- Statistical information (facts and figures) on cancer incidence and prevalence, global cancer related deaths, and new cases of cancer by type in the United States

- Review of recent industry trends, value chain analysis, competitive landscape, and COVID-19 implications within the marketplace

- Descriptive company profiles of the leading global players, including Bio-Techne Corp., Biocept Inc., Greiner Bio-One International GmbH, Precision Medicine Group LLC, Menarini Silicon Biosystems, and Qiagen N.V.

Summary:

The global market for circulating tumor cells diagnostics was valued at REDACTED in 2020. By cancer type, this market has been segmented into breast cancer, colorectal cancer and prostate cancer. The breast cancer segment recorded REDACTED in revenue in 2020 and is estimated to grow at a compound annual growth rate (CAGR) of REDACTED during the forecast period. The fast growth rate of the colorectal cancer segment is attributed to rapid rise in the incidence of colorectal cancer, especially young adults. The growing prevalence of cancer, as circulating tumor cells find their applications in the diagnosis of cancer and precision management; advancements in technologies such as NGS and immunofluorescence; and growing awareness about the novel diagnostic methods for cancers are all major factors that will boost market growth.

Reasons for Doing this Study

This study was conducted to provide detailed information regarding new developments, prognostic and clinical research testing for circulating tumor cells. There is an increasing need for new and innovative technologies in this area. This industry is experiencing tremendous growth; the use of new prognostic technologies based on circulating tumor cells has increased in the past few years.

This BCC Research study will increase awareness of current and emerging technologies and practices for cancer and cancer research, especially for prostate, breast and colorectal cancers.

Circulating Tumor Cell (CTC) Diagnostics: Technologies and Global Markets

Table of Contents
Chapter 1 Introduction
Study Background
Study Goals and Objectives
Reasons for Doing this Study
Scope of Report
What's New in this Update?
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Market and Technology Background
Cancer
Recent Advances in Technology
Invasive Power
Circulating Tumor Cells
Phenotypic Characteristics
CTC Clusters
CTC Detection
Cancer Stem Cells (CSCs)
Circulating Tumor Cells -- Potential Uses
Proliferative Activity
Epithelial Marker Genes on Circulating Tumor Cells
Circulating Tumor Cells and Stem Cell-Like Phenotype
CTCs and Primary Tumor Cells: A Comparison
Metastasis
Future Directions
Metastatic Development in Cancer Patients
Circulating Tumor Cell Migration
Circulating Tumor Cell Detection
Methods
CellSearch Method
Epic Sciences Method
Maintrac
ISET Test
Challenges for Detection
Clinical Application of Circulating Tumor DNA
Circulating Tumor Cells as Predictor of Response to Therapy
Measurement of CTCs -- Applications
Conclusion
Chapter 4 CTC Diagnostic Technologies
Finding Circulating Tumor Cells
Why CTCs?
Current CTC Detection and Isolation Methods
New Technologies for Detection
Cancer Prognosis
Nucleic Acid-Based Methods
Clinical Testing
Summary
New Emerging Technologies
Chapter 5 Impact of COVID-19 on the CTC Diagnostics Market
Overview
COVID-19 and Cancer Screening
Impact of COVID-19 on Company Revenues
Chapter 6 Market Dynamics
Market Drivers
Rising Incidence of Cancer Worldwide
Advantages Offered, by Noninvasivene Approach, by Circulating Tumor Cells
Advancements in NGS and Immunofluorescence Technologies
Growing Awareness About the Novel Diagnostic Methods for Cancers
Market Restraints
High Costs of CTC Diagnostics
Rarity of CTCs in Blood Samples and Lack of Skilled Professionals for CTC Diagnostics
Market Opportunities
Circulating Tumor Cells as a Therapeutic Target
Competitive Landscape
Chapter 7 Market Breakdown by Cancer Type
Global Market for CTC Diagnostics by Cancer Type
Breast Cancer
Colorectal Cancer
Prostate Cancer
Chapter 8 Market Breakdown by Technology
Global Market for CTC Diagnostics by Technology
CTC Enrichment and Detection
CTC Direct Detection
CTC Analysis
Chapter 9 Market Breakdown by Application
Global Market for CTC Diagnostics by Application
Clinical/Liquid Biopsy
Research
Chapter 10 Market Breakdown by Region
Global Market for CTC Diagnostics by Region
North America
Europe
Asia-Pacific
Rest of World
Chapter 11 Company Profiles
BIO-TECHNE CORP. (ADVANCED CELL DIAGNOSTICS INC.)
BIOCEPT, INC.
BIOFLUIDICA
CREATV MICROTECH INC.
FLUXION BIOSCIENCES, INC.
GREINER BIO-ONE INTERNATIONAL GMBH
IKONISYS, INC.
IVDIAGNOSTICS, INC.
MENARINI SILICON BIOSYSTEMS (FORMERLY VERIDEX LLC)
MILTENYI BIOTEC
PRECISION MEDICINE GROUP LLC
QIAGEN N.V.
RARECELLS, INC.
SCREENCELL
STEMCELL TECHNOLOGIES INC.
Chapter 12 Appendix: List of Acronyms

List of Tables
Table A : New Additions to the Updated Version of the Report
Summary Table : Global Market for Circulating Tumor Cells (CTC) Diagnostics, by Cancer Type, Through 2026
Table 1 : Categories of Stem Cells
Table 2 : Product Categories
Table 3 : Key Characteristics of CTCs
Table 4 : Types of CTCs
Table 5 : Circulating Tumor Cells Features
Table 6 : Metastatic Cascade
Table 7 : EPCAM-Based Assays
Table 8 : Comparison of Different Liquid Biopsy Technologies
Table 9 : Potential Applications of CTC-Based Diagnostics
Table 10 : Clinical Relevance of CTC
Table 11 : CTC Enrichment Methods
Table 12 : Techniques Used for CTC Enrichment
Table 13 : Techniques Used for CTC Analysis
Table 14 : Enumeration Techniques
Table 15 : Functional Assays
Table 16 : Circulating Tumor Cells Technologies
Table 17 : Micro-Count Features: A New Technology
Table 18 : Ranking of Global Vendors of CTC Diagnostics, 2020
Table 19 : Global Market for CTC Diagnostics, by Cancer Type, Through 2026
Table 20 : Global Market for CTC Diagnostics for Breast Cancer, by Region, Through 2026
Table 21 : Global Market for CTC Diagnostics for Colorectal Cancer, by Region, Through 2026
Table 22 : Global Market for CTC Diagnostics for Prostate Cancer, by Region, Through 2026
Table 23 : Global Market for CTC Diagnostics, by Technology, Through 2026
Table 24 : CTC Enrichment Methods
Table 25 : Global Market for CTC Enrichment and Detection, by Region, Through 2026
Table 26 : Global Market for CTC Direct Detection, by Region, Through 2026
Table 27 : Global Market for CTC Analysis, by Region, Through 2026
Table 28 : Global Market for CTC Diagnostics, by Application, Through 2026
Table 29 : Global Market for CTC Diagnostics in Clinical/Liquid Biopsy Applications, by Region, Through 2026
Table 30 : Global Market for CTC Diagnostics in Research Applications, by Region, Through 2026
Table 31 : Global Market for CTC Diagnostics, by Region, Through 2026
Table 32 : North American Market for CTC Diagnostics, by Cancer Type, Through 2026
Table 33 : North American Market for CTC Diagnostics, by Country, Through 2026
Table 34 : Estimated Number of New Cases and Age-Standardized Incidence Rates for Cancers in Canada, by Sex, 2020
Table 35 : European Market for CTC Diagnostics, by Cancer Type, Through 2026
Table 36 : European Market for CTC Diagnostics, by Country, Through 2026
Table 37 : Asia-Pacific Market for CTC Diagnostics, by Cancer Type, Through 2026
Table 38 : Asia-Pacific Market for CTC Diagnostics, by Country, Through 2026
Table 39 : Age-Standardized Cancer Incidence and Mortality Rates in China, by Gender, 2018
Table 40 : Rest of World Market for CTC Diagnostics, by Cancer Type, Through 2026
Table 41 : Bio-Techne Corp. (Advanced Cell Diagnostics Inc.): R&D Expenditures, 2018-2020
Table 42 : Bio-Techne Corp. (Advanced Cell Diagnostics Inc.): Products Offered
Table 43 : Bio-Techne Corp. (Advanced Cell Diagnostics Inc.): Recent Developments
Table 44 : Biocept, Inc.: R&D Expenditures, 2019 and 2020
Table 45 : Biocept, Inc.: Solutions/Services Offered
Table 46 : Biocept, Inc.: Recent Developments
Table 47 : BioFluidica: Solutions/Services Offered
Table 48 : BioFluidica: Recent Developments
Table 49 : Creatv MicroTech Inc.: Products Offered
Table 50 : Creatv MicroTech Inc: Recent Developments
Table 51 : Fluxion Biosciences, Inc.: Solutions/Services Offered
Table 52 : Fluxion Biosciences, Inc.: Recent Developments
Table 53 : Greiner Bio-One International GmbH: Products Offered
Table 54 : Ikonisys, Inc.: Products Offered
Table 55 : Ikonisys, Inc.: Recent Developments
Table 56 : IVDiagnostics, Inc.: Products/Services Offered
Table 57 : IVDiagnostics, Inc.: Recent Developments
Table 58 : Menarini Silicon Biosystems: Products Offered
Table 59 : Menarini Silicon Biosystems: Recent Developments
Table 60 : Miltenyi Biotec: Products Offered
Table 61 : Precision Medicine Group LLC: Products Offered
Table 62 : Precision Medicine Group LLC: Recent Developments
Table 63 : Qiagen: Products Offered
Table 64 : Qiagen: Recent Developments
Table 65 : Rarecells, Inc.: Products Offered
Table 66 : Rarecells, Inc.: Recent Developments
Table 67 : ScreenCell: Products Offered
Table 68 : ScreenCell: Recent Developments, 2021
Table 69 : STEMCELL Technologies Inc.: Products/Services Offered
Table 70 : STEMCELL Technologies Inc.: Recent Developments
Table 71 : Commonly Used Acronyms in the Market for CTC Diagnostics

List of Figures
Summary Figure : Global Market Shares of Circulating Tumor Cells (CTC) Diagnostics, by Cancer Type, 2020
Figure 1 : Global Market Shares of CTC Diagnostics, by Cancer Type, 2020
Figure 2 : Global Market for CTC Diagnostics for Breast Cancer, 2019-2026
Figure 3 : Global Market for CTC Diagnostics for Breast Cancer, by Region, 2019-2026
Figure 4 : Global Market for CTC Diagnostics for Colorectal Cancer, 2019-2026
Figure 5 : Global Market for CTC Diagnostics for Colorectal Cancer, by Region, 2019-2026
Figure 6 : Global Market for CTC Diagnostics for Prostate Cancer, 2019-2026
Figure 7 : Global Market for CTC Diagnostics for Prostate Cancer, by Region, 2019-2026
Figure 8 : Global Market Shares of CTC Diagnostics, by Technology, 2020
Figure 9 : Global Market for CTC Enrichment and Detection, 2019-2026
Figure 10 : Global Market for CTC Enrichment and Detection, by Region, 2019-2026
Figure 11 : Global Market for CTC Direct Detection, 2019-2026
Figure 12 : Global Market for CTC Direct Detection, by Region, 2019-2026
Figure 13 : Global Market for CTC Analysis, 2019-2026
Figure 14 : Global Market for CTC Analysis, by Region, 2019-2026
Figure 15 : Global Market Shares of CTC Diagnostics, by Application, 2020
Figure 16 : Global Market for CTC Diagnostics in Clinical/Liquid Biopsy Applications, 2019-2026
Figure 17 : Global Market for CTC Diagnostics in Clinical/Liquid Biopsy Applications, by Region, 2019-2026
Figure 18 : Global Market for CTC Diagnostics in Research Applications, 2019-2026
Figure 19 : Global Market for CTC Diagnostics in Research Applications, by Region, 2019-2026
Figure 20 : Global Market for CTC Diagnostics, by Region, 2019-2026
Figure 21 : Global Market Shares of CTC Diagnostics, by Region, 2020
Figure 22 : North American Market Shares of CTC Diagnostics, by Cancer Type, 2020
Figure 23 : North American Market Shares of CTC Diagnostics, by Country, 2020
Figure 24 : U.S. Market for CTC Diagnostics, 2019-2026
Figure 25 : Canadian Market for CTC Diagnostics, 2019-2026
Figure 26 : European Market Shares of CTC Diagnostics, by Cancer Type, 2020
Figure 27 : European Market Shares of CTC Diagnostics, by Country, 2020
Figure 28 : German Market for CTC Diagnostics, 2019-2026
Figure 29 : French Market for CTC Diagnostics, 2019-2026
Figure 30 : U.K. Market for CTC Diagnostics, 2019-2026
Figure 31 : Italian Market for CTC Diagnostics, 2019-2026
Figure 32 : Spanish Market for CTC Diagnostics, 2019-2026
Figure 33 : Rest of European Market for CTC Diagnostics, 2019-2026
Figure 34 : Asia-Pacific Market Shares of CTC Diagnostics, by Cancer Type, 2020
Figure 35 : Asia-Pacific Market Shares of CTC Diagnostics, by Country, 2020
Figure 36 : Chinese Market for CTC Diagnostics, 2019-2026
Figure 37 : Indian Market for CTC Diagnostics, 2019-2026
Figure 38 : Japanese Market for CTC Diagnostics, 2019-2026
Figure 39 : Australian Market for CTC Diagnostics, 2019-2026
Figure 40 : Rest of Asia-Pacific Market for CTC Diagnostics, 2019-2026
Figure 41 : Rest of World Market Shares of CTC Diagnostics, by Cancer Type, 2020
Figure 42 : Bio-Techne Corp. (Advanced Cell Diagnostics Inc.): Net Revenue, 2016-2020
Figure 43 : Bio-Techne Corp. (Advanced Cell Diagnostics Inc.): Revenue Share, by Business Segment, 2020
Figure 44 : Bio-Techne Corp. (Advanced Cell Diagnostics Inc.): Revenue Share, by Region, 2020
Figure 45 : Biocept, Inc.: Net Revenue, 2016-2020
Figure 46 : Greiner Bio-One International GmbH: Net Revenue, 2016-2020
Figure 47 : Greiner Bio-One International GmbH: Revenue Share, by Business Segment, 2020
Figure 48 : Greiner Bio-One International GmbH: Revenue Share, by Region, 2020
Figure 49 : Qiagen: Net Revenue, 2016-2020
Figure 50 : Qiagen: Revenue Share, by Business Segment, 2020
Figure 51 : Qiagen: Revenue Share, by Region, 2020
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