Chronic Kidney Disease: Global Markets and Technologies Through 2023

Publisher Name :
Date: 22-Apr-2019
No. of pages: 153

Report Scope:

Five-year projections for market activity and value are provided. Treatment types and trends for acute and chronic kidney failure, pricing considerations for medications, dialysis products (dialysis machines, dialysates and dialyzers), therapies, surgical procedures, companies, industry structure and participating companies are included in the study.

Qualitative information on disease overview, epidemiology and clinical burden of CKD is covered in detail. Further, detailed description about diagnostic methods such as blood tests, medical imaging; treatment, disease management strategies like pharmacological interventions, medical device interventions such as dialysis and kidney transplantation procedures and dietary supplements are covered. Further supporting technologies such as smartphone apps, tools and emerging technologies in dialysis and kidney transplantation procedures are also covered. Special emphasis is given to new, emerging technologies for the treatment of CKD. Market specific information on global dynamics (drivers, challenges and emerging opportunities) are covered. CKD disease management involves tedious labor, safety and cost analyses, knowledge of current policies, regulations and reimbursement. Further clinical trial and patent landscape is also covered in the report. Profiles and the overall competitive landscape of companies/manufacturers engaged in offering drugs and medical equipment for treating CKD is covered in the report.

Quantitative market size and forecast information is covered broadly by treatment, user settings and region. By treatment, the market is categorized into drugs (treatment of complications associated due to CKD, drugs for dialyzed patient groups, post-kidney transplantation procedures are covered) and medical equipment (dialysis-hemodialysis, peritoneal dialysis, kidney transplantation procedure surgical equipment). By user settings the CKD market is categorized into hospitals, specialty clinics and homecare. By region the market is categorized into North America, Europe, Asia-Pacific and RoW (Latin America, Middle East and Africa).

Report Includes:

- 37 data tables and 22 additional tables

- A detailed overview of the global markets for Chronic Kidney Disease (CKD)

- Analyses of global market trends with data from 2017 and 2018, and projections of compound annual growth rates (CAGRs) through 2023

- Information on current state of chronic kidney disease, with an emphasis on biomarkers, diagnostic methods, and mobile apps that support effective disease state management

- Key insight into research on CKD comorbidities such as Diabetes and Metabolic Disease, as well as treatment methods and diagnostics

- A look at the impact of regulatory, environmental, and legislative issues on the global CKD market

- Profiles of major market players within the industry, including Abbott Laboratories, Eli Lilly and Co., Eisai, Inc., Merck & Co. and Sanofi-Aventis

Summary

The healthcare sector underwent remarkable change in the last decade due to the increased use of innovative products and therapies. The evolution of dialysis technology contributes to development of the healthcare sector. Researchers focus on innovative products and machines for dialysis. Companies producing dialysis products are investing more in R&D. Home dialysis and portable dialysis machines are gaining popularity among patients suffering from end-stage kidney disease, kidney failure and acute kidney injury.

The focus of this report is the role of drugs and medical device intervention (dialysis) in the treatment and management of Chronic Kidney Disease (CKD).

The global market for CKD drugs and dialysis devices was valued at REDACTED in 2017 and is expected to witness a growth of REDACTED CAGR to reach REDACTED by 2023.

Reasons for Doing This Study

The economic impact of CKD remains a global crisis. Even with the gradual shift in treatment guidelines and innovation, nearly 10% of the U.S. population suffers from this disease that is often referred to as a silent killer. Today, one out of seven people in the U.S. have CKD. Most are unaware that they have it. Millions of patients go undiagnosed each year due to lack of treatment and affordable care. Annual treatment costs for Medicare beneficiaries with CKD are as high as $64 billion, with an additional $34 billion spent on treating patients with end stage renal disease (ESRD).

Expenditures related to kidney failure consume about 10% of the total Medicare budget, accounting for treatment of less than 1% of all Medicare recipients. The imbalance between cost and clinical outcomes associated with CKD create an impenetrable health care burden.

Kidney failure is the ninth-leading cause of death in the U.S., accounting for about 47,000 fatalities in 2013. Approximately 33 million Americans currently have CKD. Another 20 million are at increased risk for developing CKD.

More than two million people, worldwide, receive treatment: dialysis or kidney transplant. Of the subset being treated for kidney failure, the majority are treated in only five countries: the U.S., Japan, Germany, Brazil and Italy. These five countries represent only 12% of the world population. Forecasts suggest that the number of cases of kidney failure will increase disproportionately in developing countries, like China and India, where the number of elderly people is increasing.

CKD is a global health problem. This report provides a regional analysis of costs and clinical outcomes related to the management of CKD around the world. Data is further segmented by CKD stage, end user and application.

This market analysis is intended to provide analytical information to optimize business strategies. The ability to execute operating plans effectively rests on a company's ability to integrate industry research and data.

Chronic Kidney Disease: Global Markets and Technologies Through 2023

Table of Contents

Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

Chapter 2 Summary and Highlights
Key Findings

Chapter 3 Background of Chronic Kidney Disease
Kidney Function
Renal Disease
Symptoms
Hospitalization for Kidney Disease
Costs of Chronic Kidney Disease
Epidemiology of Renal Disease
Cause of Chronic Kidney Disease
Pathology of Chronic Kidney Disease
Anemia
Diabetic Nephropathy
Electrolyte Abnormality
Diagnostic Methods for Identification and Detection of Chronic Kidney Disease
Clinical Markers for the Detection of Chronic Kidney Disease
Treatment and Management of Chronic Kidney Disease (CKD)
Pharmaceutical Therapies
Antihyperkalemia
Antihyperphosphatemia
Cholesterol Management Medications
Diuretics
Erythropoiesis-Stimulating Agents
Iron Therapy
Glucose Management
Other
Medical Device Interventions
Dialysis
Kidney Transplant
Renal Dialysis
Principles of Renal Dialysis
Function of Renal Dialysis
Types of Renal Dialysis
Hemodialysis
Peritoneal Dialysis
Additional Medications for Dialysis Patients
Medications for CKD Patients on Peritoneal Dialysis
Novel Kidney Treatment in Development
Portable, Cartridge-Based Hemodialysis Device
Wearable Peritoneal Dialysis Device
Kidney Transplantation
The Transplant Procedure
Waiting List for Kidney Transplantation
Economics of Kidney Transplant
Drugs Used in Conjunction with Kidney Transplantation
Immunosuppressant Agents for Kidney Transplant
Software and Mobile Applications for Chronic Kidney Disease Management
Smartphone Technology and Mobile Apps
Mobile Apps for CKD Patients
Mobile Apps for CKD Professionals
Diet and Nutrition Apps
Medication Apps
Renal LabApps

Chapter 4 Market Overview
Overview
Factors Affecting Renal Dialysis Market
Drivers of the Renal Dialysis Market
Current Challenges for the Renal Dialysis Market
Regulations and Reimbursement Landscape
U.S. FDA 510(k) Approval
Reimbursement Landscape

Chapter 5 Market Segment Analysis
Segment Analysis, by Treatment Intervention
Pharmaceutical Drugs
Medical Device Interventions-Dialysis
Analysis of Medical Device Intervention, by Product
Analysis of Medical Device Intervention/Dialysis Market, by End User

Chapter 6 Market Breakdown by Region
North America
U.S.
Canada
Mexico
Europe
Germany
France
Italy
U.K.
Asia-Pacific
China
India
Japan
RoW
Latin America
Africa
Middle East

Chapter 7 Patent Review/ New Developments
Patents, by Year
Patents, by Type
Patents, by Company
Patents, by Country
Patents, by Assignee
New Developments
Prevention and Treatment of Chronic Kidney Disease
Use of Dynamin Ring Stabilizers
Compositions for the Treatment of Kidney Disease
Methods and Compositions in AKI
Treatment of CKD and Other Renal Dysfunction: GDF15 Modulator
Methods for Diagnosing and Assessing Kidney Disease
Treatment and Prevention of Chronic Kidney Disease
Pharmaceutical Composition for Treating Chronic Kidney Disease
Detection of Chronic Kidney Disease and Disease Progression
Methods and Composition for Diagnosis and Prognosis of Renal Injury and Renal Failure
Treatment for Chronic Kidney Disease
PromarkerD-A Predictive and Diagnostic Test for Chronic Kidney Disease

Chapter 8 Competitive Landscape
Overview
Pharmaceutical Manufacturers
Dialysis Equipment and Accessories Manufacturers
Market Share Analysis for Dialysis
Recent Industry Developments
Key Mergers and Acquisitions

Chapter 9 Company Profiles
ABBOTT LABORATORIES
ABBVIE BIOTHERAPEUTICS CORP.
ACCELERON PHARMA, INC.
ACON LABORATORIES, INC.
AKEBIA THERAPEUTICS, INC.
AM-PHARMA
AMAG PHARMACEUTICALS
AMERICAN REGENT, INC.
AMERICAN RENAL ASSOCIATES
AMGEN
ARDELYX
ARKRAY, INC.
ASAHI KASEI KURARAY MEDICAL CO.
ASTELLAS PHARMA U.S., INC.
ASTRAZENECA PLC
AURINIA PHARMACEUTICALS, INC.
ASTUTE MEDICAL, INC.
AVEO PHARMACEUTICALS, INC.
AWAK TECHNOLOGIES, INC.
B. BRAUN MEDICAL, INC.
BARD ACCESS SYSTEMS, INC.
BAXTER INTERNATIONAL, INC.
BAYER HEALTHCARE PHARMACEUTICALS LLC
BIOCAD
BOEHRINGER INGELHEIM
BRISTOL-MYERS SQUIBB
CANTEL MEDICAL
CENTERS FOR DIALYSIS CARE
CHEMOCENTRYX, INC.
CHONG KUN DANG PHARMACEUTICAL CORP.
CONCERT PHARMACEUTICALS, INC.
DAVITA, INC.
DIALYSIS CLINIC, INC. (DCI)
DIAMEDICA THERAPEUTICS, INC.
DIVERSIFIED SPECIALTY INSTITUTES (DSI)
ELI LILLY AND CO.
EISAI, INC.
FIBROGEN, INC.
FRESENIUS MEDICAL CARE (FMC)
GENENTECH, INC.
GLAXOSMITHKLINE
HOSPIRA, INC.
INCYTE CORP.
JANSSEN PHARMACEUTICALS, INC.
KERYX BIOPHARMACEUTICALS
KIDNEY CENTER, INC.
KRINGLE PHARMA, INC.
LIBERTY DIALYSIS
MEDCOMP
MEDGENICS, INC.
MEDICINES CO.
MERCK & CO.
MYLAN, INC.
NAVILYST MEDICAL
NEPHROGENEX, INC.
NIPRO CORP.
NORTHWEST KIDNEY CENTERS
NOVARTIS PHARMACEUTICALS
NOVO NORDISK A/S
NOXXON PHARMA A/G
NXSTAGE MEDICAL, INC.
OUTSET MEDICAL, INC.
PFIZER PHARMACEUTICAL
PROMETHEUS LABORATORIES, INC.
RENAL RESEARCH INSTITUTE (RRI) LLC
QUANTA FLUID SOLUTION LTD.
SANOFI-AVENTIS
SATELLITE HEALTHCARE/WELLBOUND CONCERT
SHIRE PHARMACEUTICALS GROUP
THRASOS INNOVATION
TRICIDA, INC.
U.S. RENAL CARE INC. (USRC)
VASCULAR ACCESS CENTERS
VASCULAR PHARMACEUTICALS, INC.
VIFOR PHARMA LTD.

List of Tables

Summary Table : Global Market for Chronic Kidney Disease, by Type, Through 2023
Table 1 : Stages of Chronic Kidney Disease: A Clinical Action Plan
Table 2 : Awareness, Treatment and Measures of Control of Risk Factors, 1998-2012
Table 3 : Incidence of ESRD, by Country, 2015
Table 4 : Prevalence of ESRD, by Country, 2015
Table 5 : Incidence of ESRD Patients (Due to Diabetes), by Country, 2015
Table 6 : Kidney Transplant Rates, by Country, 2015
Table 7 : Pathologies and Etiologies Associated with CKD
Table 8 : Common Medications Associated with Chronic Kidney Disease
Table 9 : Prevalence of Hypertension and Dyslipidemia, by CKD Stage
Table 10 : Patients Share of Commonly Prescribed Medication for Chronic Kidney Disease
Table 11 : Recommended Antihypertensive Agents for Patients with Chronic Kidney Disease and Hypertension
Table 12 : Commonly Prescribed Ace Inhibitors
Table 13 : Commonly Prescribed Angiotensin Receptor Blockers
Table 14 : Commonly Prescribed Beta Blockers
Table 15 : Commonly Prescribed Calcium Channel Blockers
Table 16 : Commonly Prescribed Phosphate Binders
Table 17 : Commonly Prescribed Statins
Table 18 : Commonly Prescribed Bile Acid Sequestrants
Table 19 : Commonly Prescribed Fibrates
Table 20 : Commonly Prescribed Diuretics
Table 21 : Commonly Prescribed Erythropoiesis-Stimulating Agents
Table 22 : Commonly Prescribed Iron Supplements
Table 23 : Commonly Prescribed Glucose Management Drugs
Table 24 : Commonly Prescribed Medication for Chronic Kidney Disease
Table 25 : Commonly Prescribed Immunosuppressant Drugs
Table 26 : Immunosuppression Maintenance Regimens
Table 27 : Immunosuppression Induction Drug Therapies
Table 28 : Global Market for Chronic Kidney Disease, by Type, Through 2023
Table 29 : Reimbursement of Dialysis Services per Week, 2011-2013
Table 30 : Global Market for CKD Pharmaceutical Drugs, by Type, Through 2023
Table 31 : Global Market for CKD Stage 1-5 Drugs, by Region, Through 2023
Table 32 : Common Drug Classes Used, by Part D-Enrolled Dialysis Patients, 2013
Table 33 : Global Market for Dialysis Drugs, by Region, Through 2023
Table 34 : Global Market for Post-Transplantation Drugs, by Region, Through 2023
Table 35 : Global Market for Dialysis Devices, by Type, Through 2023
Table 36 : Global Market for Hemodialysis, by Region, Through 2023
Table 37 : Key Peritoneal Products and Manufacturers
Table 38 : Global Market for Peritoneal Dialysis, by Region, Through 2023
Table 39 : Global Market for Dialysis Devices, by Product, Through 2023
Table 40 : Global Market for Dialysis Accessories, by Region, Through 2023
Table 41 : Global Market for Dialysis Equipment, by Region, Through 2023
Table 42 : Global Market for Dialysate and Other Solutions, by Region, Through 2023
Table 43 : Global Market for Dialysis Devices, by End User, Through 2023
Table 44 : Global Market for Medical Care Centers, by Region, Through 2023
Table 45 : Global Market for In-Home Dialysis, by Region, Through 2023
Table 46 : Global Market for Chronic Kidney Disease, by Region, Through 2023
Table 47 : North American Market for Chronic Kidney Disease, by Country, Through 2023
Table 48 : European Market for Chronic Kidney Disease, by Country, Through 2023
Table 49 : Asia-Pacific Market for Chronic Kidney Disease, by Country, Through 2023
Table 50 : Rest of the World Market for Chronic Kidney Disease, by Country, Through 2023
Table 51 : Patents on Renal Dialysis Equipment and Technology, by Year, 2014-2017
Table 52 : Patents on Renal Dialysis Equipment and Technology, by Type, 2014-2017
Table 53 : Patents on Renal Dialysis Equipment and Technology, by Company, 2014-2017
Table 54 : Patents on Renal Dialysis Equipment and Technology, by Country, 2014-2017
Table 55 : Patent Shares of Renal Dialysis Equipment and Technology, 2014-2017
Table 56 : Patents on Renal Dialysis Equipment and Technology, by Assignee, 2014-2017
Table 57 : New Developments in Renal Dialysis, 2014-2017
Table 58 : Key Mergers and Acquisitions in Renal Dialysis, 2014-2017

List of Figures

Summary Figure : Global Market for Chronic Kidney Disease, by Type, 2017-2023
Figure 1 : Patents on Renal Dialysis Equipment and Technology, by Year, 2014-2017
Figure 2 : Patents on Renal Dialysis Equipment and Technology, by Type, 2014-2017
Figure 3 : Patents on Renal Dialysis Equipment and Technology, by Assignee, 2014-2017
Figure 4 : Global Market Share of Dialysis Medical Devices, by Company, 2017
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