Report Scope:
This report consists of the overall analysis of the market landscape. It provides in-depth analysis on market size, growth opportunity in market and product types. The report will serve as a source for 360-degree analysis of the market, thoroughly integrating different models. The solid tumor products in clinical trials and current products available on the market have been studied thoroughly. The report also consists of a detailed overview of all the cell separation technologies and techniques. In addition, the cancer diagnostics market chapter has been provided in detail to give the overall insights in the development of cancer diagnosis technologies. R&D budget of organizations and companies in oncology research have been analyzed in detail. Different approaches have been worked on to derive the market value and market growth rate. Facts and data related to the market from different geographic areas provide a better regional outlook in the report. In the report, country level analysis is provided by analyzing various regional players, regional tax laws and policies, consumer behavior and macro-economic factors. This report will help the companies and organizations have an all-around analysis of the cell separation and characterization in the solid tumor market and the most preferred markets regionally.
Report Includes:
- 54 data tables and 36 additional tables
- An overview of the global markets and technologies for cell separation and characterization in solid tumors
- Analyses of global market trends with data from 2017 and 2018, and projections of compound annual growth rates (CAGRs) through 2023
- Overview of the main markers used for isolation, identification and purification for solid tumors, including surface cell-adhesion molecules such as CD133, CD24, hyaluronic acid (HA) receptor CD44, cytoprotective enzymes such as aldehyde dehydrogenase, ALDH, and transcription factors OCT-4, SOX-2
- Discussion of the various cell separation technique and technologies such as fluorescence-activated cell sorting (FACS), magnet-activated cell sorting (MACS), density gradient centrifugation, dielectrophoretic (DEP), aqueous two-phase system, field flow fractionation (FFF) and microfluidic platforms
- Coverage of the major products of the industry such as solid tumor kits, multi-marker solid tumor panels, reagents and microchips and micro-beads
- Comprehensive analysis of the major companies active in the market, including Abbvie, Inc., AstraZeneca, Beckman Coulter, Daiichi Sankyo and Pfizer, Inc.
Summary
The market for cell separation and characterization in solid tumor is expected to grow at a CAGR of REDACTED during the forecast period (2018-2023). It is expected to generate a market value of REDACTED by 2023. Solid tumors are the abnormal mass of tissue that does not contain cysts or liquid. Solid tumors are composed of heterogeneous populations of normal and cancerous cells. Cancerous cells that form the solid tumor includes sarcomas, carcinomas, lymphomas. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Solid tumors contain stem cells that have the ability of self-renewal and these cells must be isolated from the solid tumor as these cells give biological insights of the disease condition, progression,and treatment prediction. This will drive all the cancer research and diagnosis in the future. Solid tumors similar to abnormally developed organs and tissues are composed of many types of cells including neoplastic cells, supporting vascular cells, inflammatory cells, and fibroblasts. Most cells in bulk tumors have limited self-renewal ability and are non-tumorigenic. Only a small subpopulation of cancer cells is long-lived with the ability of extensive self-renew and tumor formation. This small population is calledCancer Stem Cells (CSCs), or Cancer Initiating Cells (CICs), or Tumor Stem Cells (TSCs). The characterization of a cell line is significant for the determination of its functionality and in proving its authenticity as a pure cell line. It indicates the possibility that the cell line has become crosscontaminated with an existing continuous cell line or misidentified due to mishandling in DNA profiling.
It has emerged as one of the major standard procedures for cell line identification, and a standard procedure with universal application. Cancer is a global concern and includes many different diseases that are all characterized by the uncontrolled growth and spread of abnormal cells. Within the broad categories of cancer (such as breast or lung cancer), there are many different types. And, even within one type of cancer, the molecular changes that caused the cancer vary with different tumors. Stem cells have also been defined in many other tumors including cancers of breast, pancreas, prostate, head and neck, colon, liver, bladder and lung.
The factors contributing towards the growth of the market include the increasing prevalence of different types of cancer, increasing R&D in stem cell research and technological advancements. Primary tumors are responsible for REDACTED of mortalities. In most cases, the main cause of mortality is the formation of metastases. Tumor initiation, metastasis formation and invasive growth are due to tumor cells with distinct -stem properties. Moreover, the inefficiency of the conventional cancer treatments such as radiation therapy and chemotherapy are furthermore propelling the need for more targeted based therapy augmenting the demand for cell isolation and characterization properties of solid tumor.
Existing therapies such as chemotherapy and radiation therapy have enhanced the length of survival after diagnosis of cancer, however have completely failed in terms of recovery. Therapeutic strategies are focusing on targeting stem cells in solid tumors. This is done with the objective to eradicate the drawbacks of chemotherapy and radiation therapy to remove stem cells that cause therapy resistance. The standard oncology treatments have incomplete and temporary effects that only shrink the tumor, and the tumor tends to relapse mainly due to the multiple resistant mechanisms existing in stem cells. Different techniques are being developed to isolate and identify the minority of stem cells among the bulk tumors; and evaluate the reasons for the failure of traditional therapies (chemotherapy, radiotherapy) and the resistant mechanisms inherent in stem cells. The investments of major pharmaceuticals such as Thermo Fisher Scientific and Biolabs LLC in this technology and new products are driving the market growth.
Cell Separation and Characterization in Solid Tumors: Global Markets Through 2023
Table of Contents
Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Intended Audience
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Market and Technology Background
Description of Market Trends
Asia-Pacific is an Emerging Market
Market Drivers
Opportunities
Limitations and Challenges
Chapter 4 Market Breakdown by Product
Solid Tumor Kits
Multi-Marker Solid Tumor Panels
Reagents
Others (Microchips, Micro-Beads)
Chapter 5 Market Breakdown by End Use
Academics
Labs and Pathologies
Companies (Biotechnology, Pharmaceutical and Contract Research Organization (CRO))
Chapter 6 Market Breakdown by Indication
Non-Cancerous Tumor
Prostate Cancer
Colorectal Cancer
Ovarian Cancer
Breast Cancer
Oral Cancer
Lung Cancer
Other Indications
Lymphoma
Thyroid Cancer
Chapter 7 Market Breakdown by Method
Biomarkers
Efflux Analysis of DNA
Dye Exclusion Assays
Others (Biopsy)
Chapter 8 Market Breakdown by Region
North America
United States
Canada
Europe
United Kingdom
Germany
France
Spain
Italy
Rest of Europe
Asia-Pacific
China
India
Japan
Rest of Asia-Pacific
Rest of the World (RoW)
Latin America
Middle East and Africa (MEA)
Chapter 9 Patent Review/New Developments
New Technologies for Cell Characterization and Isolation of Tumor Cells
Evolution of Microfluidic Chips
Laser Capture Microdissection
Evolution of Nano-Velcro Cell-Affinity Assays
Second-Generation Nano-Velcro-LMD Technology for Single-Tumor cell Isolation
Micromanipulator
Limiting Dilution
New Product Developments
Patent Analysis
Chapter 10 Analysis of Market Opportunities
Key Suppliers and Manufacturers Positioning and Strategies
AdipoGen Life Sciences
Cayman Chemical
NSJ Bioreagents
AAT Bioquest
Medical & Biological Laboratories Co., Ltd.
Medical & Biological Laboratories Co., Ltd.
Manufacturer Positioning
Pfizer Corp.
Thermo Fisher Scientific
AstraZeneca
Daiichi Sankyo
Recent Activities
R&D Activities
AbbVie, Inc.
Fluxion Biosciences
Genmab A/S
Onconova Therapeutics
Chapter 11 Company Profiles
ABBVIE, INC.
ABCODIA LTD.
ASTRAZENECA
BECKMAN COULTER
BIO-TECHNE CORP.
CELL BIOLABS, INC.
CYNVENIO BIOSYSTEMS, INC.
DAIICHI SANKYO
EISAI CO. LTD.
EPIZYME, INC.
FLUXION BIOSCIENCES, INC.
GENMAB A/S
GILEAD SCIENCES, INC.
GLAXOSMITHKLINE PLC
F. HOFFMAN-LA ROCHE LTD.
ILLUMINA, INC.
JANSSEN
JUNO THERAPEUTICS, INC.
LIDDS
MERCK
MILTENYI BIOTECH
MP BIOMEDICALS
NEOGENOMICS
NOVOCURE
ONCOMED PHARMACEUTICALS, INC.
ONCONOVA THERAPEUTICS
PERKINELMER, INC.
PFIZER, INC.
PROPANC BIOPHARMA, INC.
PSIOXUS THERAPEUTICS LTD.
REGNIX
SERACARE LIFESCIENCES
TAIHO PHARMA
TAKEDA PHARMACEUTICAL CO., LTD.
TARVEDA THERAPEUTICS
TESARO, INC.
THERMO FISHER SCIENTIFIC
List of Tables
Summary Table : Global Market for Cell Separation and Characterization in Solid Tumors, by Product Type, Through 2023
Table 1 : Use of Immunohistochemistry for Cancer Biomarker Assessment
Table 2 : Application of FISH for the Study of Solid Tumors
Table 3 : Manufacturers of Available PCR Instruments
Table 4 : MACS Products, by Miltenyi Biotec, 2018
Table 5 : Density Gradient Media Types and Their Principal Uses
Table 6 : Selection Table
Table 7 : Types of ATPS with Representative Examples
Table 8 : Applicable Force Field and Corresponding FFF Techniques
Table 9 : Microfluidic Methods for Cell Isolation
Table 10 : Technologies Driving the Future of the Cancer Diagnostic Market
Table 11 : Global Cancer Incidences, 2005 vs. 2015
Table 12 : Number of MRI Machines, by Country, 2010 vs. 2015
Table 13 : Number of CT Scanners, by Country, 2010 vs. 2015
Table 14 : Number of Mammography Machines, by Country, 2010 vs. 2015
Table 15 : List of Awareness Day Related to Cancer
Table 16 : Biomarkers for Different Types of Cancer
Table 17 : Cost of Prostate Cancer Treatment in India and the U.S., 2017
Table 18 : Global Market for Cell Separation and Characterization in Solid Tumors, by Product Type, Through 2023
Table 19 : Global Market for Solid Tumor Kits, by Region, Through 2023
Table 20 : Thermo Fisher Scientific Solid Tumor Kit
Table 21 : PerkinElmer Oncology and Solid Tumor Kit Specification
Table 22 : Global Market for Multi-Marker Solid Tumor Panels, by Region, Through 2023
Table 23 : Commercially Available Multi-Marker Solid Tumor Panels Using NGS
Table 24 : Global Market for Reagents, by Region, Through 2023
Table 25 : MLPA Solutions for Solid Tumors
Table 26 : Global Market for Other Products, by Region, Through 2023
Table 27 : Microbeads Offered, by Miltenyi Biotec
Table 28 : Global Market for Cell Separation and Characterization in Solid Tumors, by End Use, Through 2023
Table 29 : Global Market for Academics, by Region, Through 2023
Table 30 : Major Research Institutes and the Solid Tumor Treatment Offered
Table 31 : Global Market for Labs and Pathology, by Region, Through 2023
Table 32 : Commonly Used Molecular Diagnostic Techniques
Table 33 : Global Market for Companies, by Region, Through 2023
Table 34 : Major Companies and their Product Portfolio
Table 35 : Global Market for Cell Separation and Characterization in Solid Tumors, by Indication, Through 2023
Table 36 : Global Market for Non-Cancerous Tumor, by Region, Through 2023
Table 37 : Global Market for Prostate Cancer, by Region, Through 2023
Table 38 : Global Market for Colorectal Cancer, by Region, Through 2023
Table 39 : Colorectal Cancer Biomarkers
Table 40 : Global Market for Ovarian Cancer, by Region, Through 2023
Table 41 : Ovarian Carcinoma-Specific Over-Expressed Markers
Table 42 : Global Market for Breast Cancer, by Region, Through 2023
Table 43 : List of Biosimilars for Breast Cancer in Phase III Trials
Table 44 : Global Market for Oral Cancer, by Region, Through 2023
Table 45 : Global Market for Lung Cancer, by Region, Through 2023
Table 46 : Clinically Relevant Biomarkers for Lung Cancer
Table 47 : Global Market for Other Indications, by Region, Through 2023
Table 48 : Global Market for Cell Separation and Characterization in Solid Tumor, by Method, Through 2023
Table 49 : Global Market for Biomarkers, by Region, Through 2023
Table 50 : Global Market for Efflux Analysis of DNA, by Region, Through 2023
Table 51 : Global Market for Dye Exclusion Assays, by Region, Through 2023
Table 52 : Global Market for Other Methods, by Region, Through 2023
Table 53 : North American Market for Cell Separation and Characterization in Solid Tumor, by Product Type, Through, 2023
Table 54 : North American Market for Cell Separation and Characterization in Solid Tumor, by End Use, Through 2023
Table 55 : North American Market for Cell Separation and Characterization in Solid Tumor, by Indication, Through 2023
Table 56 : North American Market for Cell Separation and Characterization in Solid Tumor, by Method, Through, 2023
Table 57 : North American Market for Cell Separation and Characterization in Solid Tumor, by Country, Through 2023
Table 58 : The U.S. Expenditures in Medical and Healthcare Research, 2013-2015
Table 59 : Estimated New Cases and Fatalities of Cancer in the U.S., 2017
Table 60 : Distribution of Projected New Cancer Cases in Canada, by Cancer Type, 2017
Table 61 : Canadian Market for Investments Made in Cancer Research, by Organization, 2015
Table 62 : European Market for Cell Separation and Characterization in Solid Tumor, by Product Type, Through 2023
Table 63 : European Market for Cell Separation and Characterization in Solid Tumor, by End Use, Through 2023
Table 64 : European Market for Cell Separation and Characterization in Solid Tumor, by Indication, Through 2023
Table 65 : European Market for Cell Separation and Characterization in Solid Tumor, by Method, Through 2023
Table 66 : European Market for Cell Separation and Characterization in Solid Tumor, by Country, Through 2023
Table 67 : Twenty Most Common Cancer Diseases in the U.K., 2015
Table 68 : Major Cancer Organizations in Germany
Table 69 : Asia-Pacific Market for Cell Separation and Characterization in Solid Tumor, by Product Type, Through 2023
Table 70 : Asia-Pacific Market for Cell Separation and Characterization in Solid Tumor, by End Use, Through 2023
Table 71 : Asia-Pacific Market for Cell Separation and Characterization in Solid Tumor, by Indication, Through 2023
Table 72 : Asia-Pacific Market for Cell Separation and Characterization in Solid Tumor, by Method, Through 2023
Table 73 : Asia-Pacific Market for Cell Separation and Characterization in Solid Tumor, by Country, Through 2023
Table 74 : Common Cancer Incidences in India, 2015
Table 75 : Regional Cancer Centers in India
Table 76 : Rest of World Market for Cell Separation and Characterization in Solid Tumor, by Product Type, Through 2023
Table 77 : Rest of World Market for Cell Separation and Characterization in Solid Tumor, by End Use, Through 2023
Table 78 : Rest of World Market for Cell Separation and Characterization in Solid Tumor, by Indication, Through 2023
Table 79 : Rest of World Market for Cell Separation and Characterization in Solid Tumor, by Method, Through 2023
Table 80 : Rest-of-World Market for Cell-Separation and Characterization in Solid Tumor, by Country, Through 2023
Table 81 : Community Health Grant in Latin America
Table 82 : Estimated Brazilian Cancer Incidences, by Gender, 2016
Table 83 : Research Institutes in Middle East
Table 84 : Research Institutes in Africa
Table 85 : Some of the Urinary and Serological Proteomic Biomarkers Discovered in Prostate Cancer in a South African Cohort
Table 86 : Comparison of All Cell Isolation Technologies
Table 87 : Patent Analysis in Selected Countries for Global Cell Separation and Characterization in the Solid Tumor Market, by Category
Table 88 : Number of Patents in Global Cell Separation and Characterization in the Solid Tumor Market, by Key Players, Jan. 2016-May 2018
Table 89 : Patents Granted in Global Cell Separation and Characterization in Solid Tumor Market, Jan. 2016-May 2018
List of Figures
Summary Figure : Global Market for Cell Separation and Characterization in Solid Tumors, by Product Type, 2017-2023
Figure 1 : Immunohistochemistry-Staining Method
Figure 2 : Cell Sorting Machine
Figure 3 : Common Diagnostic Tests Used for Cancer Diagnostic
Figure 4 : Global Market Share of Personalized Medicine Under Development, 2016
Figure 5 : Global Market Share of Oncology Personalized Medicine, 2016
Figure 6 : Global Cancer Moon-Shot Budget Allocation, 2017-2023
Figure 7 : UK Cancer Research Funding of Major Cancers, by Type, 2016-2017
Figure 8 : APAC Countries Cancer Demographics, 2016
Figure 9 : Biomarkers Used for Cell Separation and Characterization in Solid Tumors
Figure 10 : North American Market Share in Healthcare Expenditure, by Country, 2016
Figure 11 : Canadian Cancer Facts, 2017
Figure 12 : Canadian Market Share for Investments Made for Cancer Research, by Organization Type, 2015
Figure 13 : Cancer Mortalities in the U.K., 2011-2017
Figure 14 : Cancer Mortalities in Germany, 2011-2017
Figure 15 : Prevalence of Breast Cancer in Germany, 2018
Figure 16 : Cancer Mortalities in France, 2011-2017
Figure 17 : Spanish Population Share, by Age Structure, 2017
Figure 18 : Cancer Mortalities in Spain, 2011-2017
Figure 19 : Cancer Mortalities in Italy, 2011-2017
Figure 20 : Rest of the European Countries with High Cancer Mortalities, 2014
Figure 21 : Chinese Expenditure in Healthcare Research, 2016
Figure 22 : Cancer Mortalities in Japan, 2010-2014
Figure 23 : Population Aged 65 and Above in Japan, 2013-2016
Figure 24 : Conventional Solid Tumor Isolation Techniques
Figure 25 : Product Developments During, 2017-2018
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